Grup d’Investigació Oncològica, Translacional, Epidemiològica i Clínica (GIOTEC)

ONCOLOGIA
OBJECTIUS

• Investigación clínica en las principales localizaciones tumorales mediante ensayos Fase I, Fase II, Fase III y estudios de vida real (Real World Studies), con el objetivo de ofrecer a los pacientes oncológicos la posibilidad de ser tratados con nuevas moléculas anticipándonos a su comercialización.

• Estudios multiómicos traslacionales (genómica, epigenómica, transcriptómica y metabolómica) a partir de biofluidos de pacientes oncológicos, con objetivos diagnósticos, pronósticos, y predictivos de respuesta a tratamientos antineoplásicos.

• Investigación en epidemiología del cáncer tanto des del punto de vista descriptivo como analítico a partir de los resultados del Registro Poblacional de Cáncer de Tarragona, en colaboración con REDECAN (Red Española de Registros de Cáncer).

• Combinación interdisciplinar de estudios epidemiológicos, clínicos y traslacionales.

RESPONSABLES
  • Dr. Joan Lluís Borràs Balada

  • Dr. Josep Gumà Padró

  • Línies de recerca
  • Estructures i tesis
  • Projectes
  • Membres del grup
  • Transferència
  • Xarxes
  • Publicacions
  • Contacte

Recerca clínica
Responsable: Dr. Joan Borràs Balada
Coordinadora d’estudis: Berta Caballé Gutiérrez

a.  Assajos clínics en fase II i III, y Real-World Studies les principals localitzacions tumorals.
b.  Assajos clínics tipus “Basket Trial” per a tumors amb determinades mutacions genètiques.
c.  Estudis de factors pronòstics i predictius de resposta.

 

Recerca epidemiològica
Responsable: Dr. Jaume Galceran

a.  En el camp de la recerca epidemiològica, se centra en estudis de base  poblacional relacionats amb el Registre de Càncer de Tarragona.
b.  En el camp de la recerca en prevenció, se centra en estudis relatius als cribratges de càncer.

 

Recerca bàsica i translacional (Responsable Dr. Josep Gumà)
El grup de recerca se centra en l’estudi genòmic i metabòlic del càncer, incloent-hi la identificació de mutacions hereditàries i la recerca de biomarcadors de resposta al tractament. També investiguen el paper de la microbiota intestinal en la resposta a immunoteràpia i el seu ús en el diagnòstic precoç del càncer.

  1. Càncer de mama i ovari hereditari (CMOH)

Responsable: Dra. Marta Rodríguez

  1. Metabolòmica avançada i càncer

Responsable: Dra. Raquel Cumeras

  1. Microbioma i càncer

Responsable: Dr. Josep Gumà

  1. Oncologia de precisió

Responsable: Dr. Francesc Riu

 

Recerca en psicooncologia
Responsable: Dra. Agustina Sirgo

Estudiar l’impacte de la malaltia oncològica. A nivell social, l’estudi dels beneficis del grup d’autoajuda de dones amb càncer de mama.

    Estructures

  • Unitat de Recerca Clínica Oncològica (URCO): estructura on es duen a terme els Assajos Clínics de l’Institut d’Oncologia de la Catalunya Sud. Compta amb coordinadors d’estudis, bioinformàtics i administratius.

    El coordinador del grup és el Dr. Joan Borràs Balada.

  • Unitat de Patologia Molecular Oncològica (UPMO): estructura creada a partir de la col·laboració dels serveis d’Oncologia i d’Anatomia Patològica de l’Hospital Universitari Sant Joan de Reus. Hi participen els metges del Servei d’Oncologia Mèdica, els biòlegs de la Unitat de de Càncer Hereditari i els metges i biotecnòlegs del Servei d’Anatomia Patològica.

    Els coordinadors d’aquesta estructura són el Dr. Josep Gumà Padró i el Dr. Francesc Riu Ferrando.

  • Servei d’Epidemiologia i Prevenció del Càncer (SEPC): servei de l’Hospital Universitari Sant Joan de Reus dedicat a la recerca epidemiològica i al registre poblacional del càncer.

    El coordinador del grup és el Dr. Jaume Galceran Padrós.

     

     

     

    Tesis

  • Impact of fatty acid metabolism in breast cancer peritumoral tissue. Clinical and pathogenic aspects.
    Author: Jose Adriá Cebrián
    Directors: Dr. Josep Gumà Padró, Dr. Sandra Guaita Esteruelas
    Doctoral Program at Universitat Rovira i Virgili: Biomedicine
    Defense Date: 2022, May 6.

    Grade: Excellent Cum Laude (maximum grade in Spanish University system)
    Current job: Medial writer at Novarti

  • Axillary salvage after neoadjuvant chemotherapy in cN1 breast cancer patients: combined sentinel node-axillary ROLL technique
    Author: Jordi Fuentes Manuel
    Director: Josep Gumà Padró
    Doctoral Program at Universitat Rovira i Virgili: Biomedicine
    Defense Date: 2022, July 8
    Grade: Excel·lent Cum Laude (maximum grade in Spanish University system)

    Current job: Head of Nuclear medicine department of Hospital Universitari Sant Joan de Reus

  • Application of omic techniques to improve the diagnosis of hereditary breast and ovarian cancer syndrome
    Author: Marta Rodríguez Balada.
    Directors: Lourdes Martorell, Dr. Josep Gumà Padró
    Doctoral Program at Universitat Rovira i Virgili: Biomedicine
    Defense Date: 2020, November 13
    Grade: Excel·lent Cum Laude (maximum grade in Spanish University system)

    Current job: Head of a GIOTEC’s research line. Head of the genetic counseling unit of Institut d’Oncologia de la Catalunya Sud

  • Usefulness of cognition-guided biopsies by MRI to improve the detection of prostate cancer
    Author: José García Bennett
    Directors: Joan Carles Vilanova Busquets, Dr. Josep Gumà Padró
    Doctoral Program at Universitat Rovira i Virgili: Biomedicine
    Defense Date: 2018, March 12
    Excel·lent Cum Laude (maximum grade in Spanish University system)

    Current job: Radiologist at Hospital Univ. de Bellvitge.

  • Epidemiología de las neoplasias malignas de ovario en Tarragona, 1980-2005.
    Author: Antonio Llueca Abella.
    Directors: Joan Lluís Borràs Balada, Dr. Josep Gumà Padró.
    Doctoral Program at Universitat Rovira i Virgili: Biomedicine
    Defense Date: 2012
    Apt Cum Laude

  • Epidemiologia de les neoplàsies limfoides a les comarques de Tarragona, 1980-2004
    Author: Josep Gumà Padró
    Director: Joan Lluís Borràs Balada
    Doctoral Program at Universitat Rovira i Virgili: Biomedicine
    Defense Date: 2010

    Research projects

  • 2021 LLAV 00050: Urinary ionomics in colorectal cancer progression (ORION).
    IP: Cumeras Olmeda, Raquel.
    Team member: Gumá Padró, José; Roig Bourgine, Bàrbara; Llambrich Rodríguez, María.
    Duration: 2022-2023.
    Funding entity: Agència de Gestió d’Ajuts Universitaris i de Recerca.

  • DTS21/00113: Test de diagnóstico colorrectal para un cribado óptimo del paciente (COLOOPT Dx).
    IP: Cumeras Olmeda, Raquel.
    Team member: Riu Ferrando, Francisco Pedro; Díaz Fernández, Maria Luisa; Correig Blanchar, Xavier; Gumà Padró, José; Roig Bourgine, Bàrbara; Ballesté Peris, Belén; Quer Boniquet, Juan Carlos; Martínez Cerezo, Francisco José; Galcerán Padrós, Jaume Josep Maria; Cabezas Montero, Inés María.
    Duration: 2022-2023.
    Funding entity: Instituto de Salud Carlos III.

  • COLOOPT Dx Colorectal diagnostic test for an optimal patient screening
    Principal Investigator: Raquel Cumeras
    Reference: DTS21/00113
    Funding body: ISCIII, Instituto de Salud Carlos III
    Budget: 103.400 €
    Period: 01/01/2022-31/12/2023

  • RRHmet Predictive plasmatic metabolomic profile of germline mutations involved in DNA Homologous Recombination Repair
    Principal Investigator: Josep Gumà. Co-PI: Raquel Cumeras.
    Reference: PR-010/2022
    Funding body.: Lliga contra el càncer de les Comarques de Tarragona i Terres de l’Ebre
    Budget:500 €
    Period: 15/12/2022-14/12/2023

  • INVESTIGO Postdoc contract
    Principal Investigator: Raquel Cumeras.
    Reference: PR-010/2022
    Funding body.: AGAUR, Agència de Gestió d’Ajuts Universitaris i de Recerca
    Budget:218 €
    Period: 23/12/2022-21/12/2024

  • ORION Urinary ionomics in the progression of colorectal cancer
    Principal Investigator: Raquel Cumeras, co-PI: Maria Llambrich
    Reference: 2021 LLAV 00050
    Funding body: AGAUR, Agència de Gestió d’Ajuts Universitaris i de Recerca
    Budget: 20.000 €
    Period: 12/10/2022-11/07/2023

  • COLOVOC Reliable and specific urinary biomarkers for colorectal cancer
    Principal Investigator: Raquel Cumeras (IISPV)
    Reference: 798038
    Funding body: EU Marie Skłodowska-Curie Actions call Individual Fellowships as Outgoing
    Participants: UC Davis (US), IISPV (ES), and Biosfer Teslab SL (ES)
    Budget: 257.191 €.
    Period: 01/07/2019 – 29/04/2023

  • MetBioCan Metabolomics from biofluids in cancer
    Principal Investigator: Josep Gumà. Co-PI: Raquel Cumeras.
    Reference: PR-003/2022
    Funding body.: Lliga contra el càncer de les Comarques de Tarragona i Terres de l’Ebre
    Budget:830 €
    Period: 15/07/2022-14/11/2022

  • LIFE FLUIDS Which fluids do we have in the human body?
    Principal Investigator: Raquel Cumeras
    Reference: 415
    Funding body: Fundació Catalana per a la Recerca i la Innovació
    Budget: 3.805 €
    Period: 01/01/2022-31/12/2022

  • Suport a Grups de Recerca (SGR) URV – IISPV finançament – Grup de Recerca consolidat.
    Principal Investigator: Josep Gumà
    Reference: 2021 SGR 00818
    Funding body: AGAUR, Agència de Gestió d’Ajuts Universitaris i de Recerca
    Period: 31/12/2021-30/12/2024

  • Suport a Grups de Recerca (SGR) URV – IISPV finançament – Grup de Recerca consolidat.
    Principal Investigator: Joan Lluís Borràs Balada
    Reference: 2017 SGR 00628
    Funding body: AGAUR, Agència de Gestió d’Ajuts Universitaris i de Recerca
    Period: 2017 – 2021

     

     

     

    Participation in research projects

  • TargetML Developing a Signal Processing Pipeline for Targeted Quantitative Metabolomics and Machine Learning-Based Discovery of Volatile Biomarkers: Application to Cancer Screening
    Principal Investigator: Jesús Brezmes Llecha
    Reference: PID2021-126543OB-C22
    Participating GIOTEC members: Inés Cabezas, Cristina Miracle, Josep Gumà, Raquel Cumeras
    Funding entity: MCIN/AEI/10.13039/501100011033 and, as appropriate, by “ERDF A way of making Europe”, by the “European Union” or by the “European Union NextGenerationEU/PRTR”
    Budget: 323 €
    Period: 01/09/2022 – 31/08/2025

  • OMIVECA Development and validation of a metabolomic score for pro-vegetarian diets and its relationship with metabolic pathways implicated in cancer
    Principal Investigator: Esther Molina (UGR), Dr. Adela Castelló (ISCIII, CNE).
    Reference: TED2021-130081B-C21
    Participating GIOTEC members: Raquel Cumeras
    Funding entity: CIBER, Centro de Investigación Biomédica en Red
    Budget: 49.600 €
    Period: 01/01/2023 – 31/12/2024

  • CAROL A comprehensive Computer-Aided diagnosis (CAD) system based on RadiOlogic digitaL image biomarkers for prognosis of breast cancer relapse
    Principal Investigator: Domènec Savi Puig Valls (URV)
    Reference: TED2021-130081B-C21
    Participating GIOTEC members: Josep Gumà Padró, Kepa Amillano Parraga
    Funding entity: MCIN/AEI/10.13039/501100011033 and, as appropriate, by “ERDF A way of making Europe”, by the “European Union” or by the “European Union NextGenerationEU/PRTR”
    Budget: 085 €
    Period: 01/12/2022 – 30/11/2024

  • SCARLET A comprehensive Computer-Aided diagnosis (CAD) system based on RadiOlogic digitaL image biomarkers for prognosis of breast cancer relapse
    Principal Investigator: Carlos López Pablo (IISPV)
    Reference: TED2021-130081B-C22
    Participating GIOTEC members: Josep Gumà Padró, Kepa Amillano Parraga
    Funding entity: MCIN/AEI/10.13039/501100011033 and, as appropriate, by “ERDF A way of making Europe”, by the “European Union” or by the “European Union NextGenerationEU/PRTR”
    Budget: 785 €
    Period: 30/11/2022 – 29/11/2024

  • MetLung Metabolomic profiles in blood and urine as predictors of response to immunotherapy in lung cancer patients
    Principal Investigator: Christopher Papandreou (IISPV)
    Reference: PI20/01094
    Funding entity: ISCIII, Instituto de Salud Carlos III
    Budget: 070 €
    Period: 2021 – 2023

  • TensorChrom Signal and data processing workflow for 2D chromatography based on multi-way algorithms: Application to urine metabolomics data for colorectal cancer
    Principal Investigator: Jesús Brezmes Llecha
    Reference: RTI2018-098577-B-C21
    Funding entity: MCIN/AEI/10.13039/501100011033 and, as appropriate, by “ERDF A way of making Europe”, by the “European Union” or by the “European Union NextGenerationEU/PRTR”
    Budget: 275 €
    Period: 01/01/2019 – 31/08/2022

  • RadioCancers Robust radiomic features with clinical data modelling for characterizing common cancers aggressiveness and prognosis through computer analysis of multimodal radiological image
    Principal Investigator: Domènec Savi Puig Valls
    Reference: PID2019‐105789RB‐I00
    Funding entity: MCIN/AEI/10.13039/501100011033 and, as appropriate, by “ERDF A way of making Europe”, by the “European Union” or by the “European Union NextGenerationEU/PRTR”
    Budget: 611 €
    Period: 2020 – 2022

  • LLAVOR Colorectal cancer markers for the selection and optimization of appropriate treatments
    Principal Investigator: Xavier Correig (URV), co-PI: Raquel Cumeras (URV)
    Reference: 2018 LLAV 00072
    Participating GIOTEC members: Josep Gumà
    Funding body: AGAUR, Agència de Gestió d’Ajuts Universitaris i de Recerca
    Budget: 20.000 €
    Period: 10/10/2020-09/04/2020

  • Modelo predictivo de supervivencia poblacional del cáncer de mama según el estadio, el subtipo molecular en el momento del diagnóstico y la adherencia al tratamiento
    Principal Investigator: Ramon Clèries Soler (IDIBELL)
    Reference: PI18/01836
    Participating GIOTEC members: Alberto Ameijide Sánchez, Marià Carulla Areste
    Funding entity: ISCIII, Instituto de Salud Carlos III
    Budget:560 €
    Period: 2019 – 2021

  • Estimación del riesgo individual de cáncer de mama según factores de riesgo conocidos de la mujer para la personalización del cribado mamográfico poblacional
    Principal Investigator: Marta Román Expósito (IMIM)
    Reference: PI17/00047
    Participating GIOTEC members: Francina Saladié Roiget
    Funding entity: ISCIII, nstituto de Salud Carlos III
    Budget:760 €
    Period: 2018 – 2020

Investigadors principals: Joan Lluís Borràs Balada, Josep Gumà Padró

Investigadors: Kepa Amillano Parraga, Inés María Cabezas Montero, Francisca Martínez Madueño, Cristina Martí Blanco, Sergio Peralta Muñoz, Mireia Melé Olivé, Cinta Albacar Miró, Maria Masvidal Hernández, María José Miranda Pallarés, Jana Repkovà, David Ricardo Bottaro Parra, Raquel Cumeras Olmeda, Lola Delamo Palomares, Marc Grifoll Escoda, Cristina Miracle Huguet, Alberto Ameijide Sánchez, Xavier Cardó Moreno, Maria Carulla Areste, Sara Fernández Castillejo, Jaume Josep Maria Galceran Padrós, Sandra Merino Varela, Dulcenombre Maria Rodríguez Mesa, Marta Rodríguez Balada, Bàrbara Roig Bourgine, Beatriz Rubio Cantavella, Belén Ruiz Aguado, Francina Saladié Roiget, Sara Serrano Solares, Agustina Sirgo Rodríguez, Anna Vidal Rodríguez, Francisco Pedro Riu Ferrando, David Parada Domínguez, Karla Beatriz Peña González, Clara Beatriz Lucía Gozálvez, Jàmnica Bigorra Román, Claudia Pla González, Xavier Collado Castro, Alba Cochs Sarobe, Alexandra Cabré Pedrosa, Araceli Jiménez López, Berta Caballé Gutiérrez, Maria Teresa Parejo Arrondo, Margarita Moreno Mancho, Mònica Salvat Casas, Montserrat Querol García, Maria Murphy Colomé, Pilar Cervelló Arán, Sheila García Samaniego, Alba Lucena Gaspar, Anna Feliu Prius, Ana María Jiménez Santamaria, Ana Vidaller Ramón, Anna Maria Bonada Sanjaume, Arnau Guillemat Novo, Immaculada Concepció Grau Farrús, Jacqueline Cimerman, Jordi Civit Oró, JULIA SERRA OLTRA, Laura Quintana Berto, Maria Vidal Escudé, Ona Pallisé Subirats, Salvador Martínez Soriano, Sandra Mateu Riba

Técnico: Rocío López Rubio, Berta Mas Oliver, Cecília González Gómez-Navarro, Maria Dolors Salsench Boronat, Fabiola Medina Barajas, Laia Fortuny Parull, Laura Costa Claret

    Guies de pràctica clínica

  • Propietat industrial i intel·lectual Software
    Romera P, Villalba H, Llambrich M, Cumeras R. “Human biofluids composition: saliva and breath as life fluids” registered at SafeCreative w/ reference 2306124568135 (June 16, 2023).

    Projectes d’innovació
    Recur Detect: Early detection of recurrence and metastasis Test.
    PI: Raquel Cumeras.
    Team member: Maria Llambrich, Núria Amigó, Josep Gumà.
    Duration: 2023-2023.
    Funding entity: Intellectual Property CALL2023.

  • Gumà J, et al., SEOM-GOTEL clinical guidelines on diffuse large B cell lymphoma. Clin Transl Oncol. 2023; In Press.

  • Aldea A, Arriola E, Borràs JM, Bosch J, Carreras MJ, Conde D, Córdoba JF, Felip E, Fontanals S, Guarga L, Majem M, Mangues I, Martínez J, Moreno E, Nadal E, Peralta S, Rodríguez MC, Serrano G, Vilà L, Viñolas N. Coordination: Gasol M, Gay D, Guarga L, Martínez J, Puig G, Sancho A. Management: Pontes C, Vallano A. Programa d’harmonització farmacoterapèutica. Pautes per a l’harmonització del tractament farmacològic del càncer de pulmó no microcític metastàtic. Versió 2.0. Barcelona: Servei Català de la Salut. Departament de Salut. Generalitat de Catalunya; 2022.

  • Aparicio J, Terrasa J, Durán I, Germà-Lluch JR, Gironés R, González-Billalabeitia E, Gumà J, Maroto P, Pinto A, García-Del-Muro X. SEOM clinical guidelines for the management of germ cell testicular cancer (2016). Clin Transl Oncol. 2016 Dec;18(12):1187-1196. DOI: 10.1007/s12094-016-1566-1 . Epub 2016 Nov 4. PMID: 27815687; PMCID: PMC5138244.

  • Rueda Domínguez A, Alfaro Lizaso J, de la Cruz Merino L, Gumá i Padró J, Quero Blanco C, Gómez Codina J, Llanos Muñoz M, Martinez Banaclocha N, Rodriguez Abreu D, Provencio Pulla M. SEOM clinical guidelines for the treatment of Hodgkin’s lymphoma. Clin Transl Oncol. 2015 Dec;17(12):1005-13. DOI: 10.1007/s12094-015-1429-1 . Epub 2015 Oct 26. PMID: 26497354; PMCID: PMC4689754.

  • Provencio Pulla M, Alfaro Lizaso J, de la Cruz Merino L, Gumá i Padró J, Quero Blanco C, Gómez Codina J, Llanos Muñoz M, Martinez Banaclocha N, Rodriguez Abreu D, Rueda Domínguez A. SEOM clinical guidelines for the treatment of follicular non-Hodgkin’s lymphoma. Clin Transl Oncol. 2015 Dec;17(12):1014-9. DOI: 10.1007/s12094-015-1437-1 . Epub 2015 Nov 19. PMID: 26586117; PMCID: PMC4689757.

  • El Registre de Càncer de Tarragona és membre de la Red Española de Registros de Cáncer (REDECAN). Així mateix, diversos membres del Registre de Càncer de Tarragona van realitzar tasques en vàries línies de treball d’aquesta xarxa. Des de l’any 2017 el Dr. Jaume Galceran és el president d’aquesta xarxa.

  • El Registre de Càncer de Tarragona és membre de la Xarxa Europea de Registres de Càncer (European Network of Cancer Registries –ENCR-) i de l’Associació Internacional de Registres de Càncer (International Association of Cancer Registries –IACR-).

  • El Dr. Jaume Galceran és membre de l’Steering Committee del Groupe pour l’Epidémiologie et l’Enregistrement du Cancer dans les Pays de Langue Latine (GRELL).

  • La Dra. Raquel Cumeras co-lidera un grup de treball de la Metabolomics Quality Assurance and Quality Control Consortium (mQACC)

  • Participació de membres del grup en els grups cooperatius oncològics:

    • GECP: Grupo Español de Investigación en Cáncer de Pulmón.
    • Grupo GEICAM de Investigación en Cáncer de Mama.
    • GEICO: Grupo Español de Investigación en Cáncer de Ovario.
    • GEINO: Grupo Español de Investigación en Neurooncología.
    • GEIS: Grupo Español de Investigación en Sarcomas.
    • GEM: Grupo Español Multidisciplinar de Melanoma.
    • GEMCAD: Grupo Español Multidisciplinar en Cáncer Digestivo.
    • GETICA: Grupo Español de Terapias Inmuno-Bioloógicas en Cáncer.
    • GETNE: Grupo Español de Tumores Neuroendocrinos y Endocrinos.
    • GG: Grupo Germinal Oncológico.
    • GOTEL: Grupo Oncológico para el Tratamiento de las Enfermedades Linfoides.
    • SOGUG: Grupo Español de Oncología Genitourinaria.
    • SOLTI
    • TTCC: Grupo Español de Tratamiento de Tumores de Cabeza y Cuello.
    • TTD: Grupo Español de Tratamiento de los Tumores Digestivos
  • Participació en xarxes d’innovació:

  • Participació de membres del grup en altres consorcis:

    ERG expression is not predictive of outcome in patients with intermediate- and high-risk localized prostate cancer treated with combined androgen blockade and radiotherapy

    Henriquez, I, Malave, B, Benitez-Gabella, G, Parada, D, Canela, M, García-Pablo, R, Benavides, R, Rius, F, Arenas, M. 01/02/2026. Clinical & Translational Oncology. 28. PMID: 40788562. doi: 10.1007/s12094-025-04016-7

    Incidence and Survival of Cutaneous Squamous Cell Carcinoma: A Spanish Multicenter Population-Based Study.

    Fernández-Martínez NF, Redondo-Sánchez D, Ameijide A, Carulla M, Rubió-Casadevall J, Marcos-Gragera R, Guevara M, Gasque A, García-Doval I, Arias-Santiago S, Galceran J, Sánchez MJ. 01/01/2026. ACTAS DERMO-SIFILIOGRAFICAS. 117. PMID: 41344612. doi: 10.1016/j.ad.2025.104490

    Survival trends and cure rates of hematological neoplasms in the Spanish pediatric population.

    Trallero J, Romaguera A, Ameijide A, Cañete A, Pardo E, Alfonso P, Jeghalef-El-Karoui N, De-La-Cruz M, Onaindia-Agundez A, Sanvisens A, Redondo-Sánchez D, Perucha J, Ruiz-Armengol P, Chirlaque MD, Guevara M, Gutiérrez P, Pla C, Merino-Perera S, Garrido-Martín M, Vizcaino-Batlles A, Lopez-de-Munain A, Marcos-Gragera R. 01/01/2026. European Journal Of Epidemiology. 41. PMID: 40991150. doi: 10.1007/s10654-025-01306-w

    Use of population-based cancer registry data to evaluate organized breast cancer screening programmes in Europe by mode of detection: a scoping review.

    Kam W, Guillaume E, Rollet Q, Petrova D, Fernández-Martínez NF, van Herck K, Carulla M, Pla C, Saladié F, Miracle C, Zadnik V, Tomšic S, Cowppli-Bony A, Launoy G, Backes C. 10/06/2026. European Journal Of Public Health. 36. PMID: 42309527. doi: 10.1093/eurpub/ckag090

    Clinical and Molecular Evaluation of HER2-Low and HER2-Ultralow Breast Cancer in the Penelope-B Clinical Trial Cohort.

    Denkert C, Rachakonda S, Pehl A, Marmé F, Martin M, Karn T, Untch M, Bonnefoi H, Kim SB, Hirmas N, Bear H, Witkiewicz AK, Im SA, DeMichele A, Van’t Veer L, McCarthy N, Stiewe T, Jank P, Gelmon KA, García-Sáenz JA, Westhoff C, Kelly CM, Reimer T, Olivé MM, Knudsen ES, van Mackelenbergh M, Rojo F, Frickel N, Fasching PA, Teply-Szymanski J, Toi M, Rugo HS, Gnant M, Makris A, Felder B, Nekljudova V, Loibl S. 01/06/2026. Modern Pathology. 39. PMID: 42025846. doi: 10.1016/j.modpat.2026.101006

    A chemotherapy-free, pathological response-adapted strategy using trastuzumab-pertuzumab and T-DM1 in HER2-positive early breast cancer: the PHERGain-2 study.

    Garrigós L, Ruiz-Borrego M, Pérez-García JM, Guerrero-Zotano A, Cortés-Salgado A, Kuemmel S, Colleoni M, Reboredo-Rendo C, Bermejo B, Blancas I, Gavila J, Fabi A, Morales C, Stradella A, Carañana V, Martínez-de Dueñas E, Albacar C, Ballesteros-Cidras O, Martrat G, Iacobucci S, Boix O, Berenguer-Molins P, Alcalá-López D, Cortés J, Llombart-Cussac A. 01/06/2026. Annals Of Oncology. 37. PMID: 42097893. doi: 10.1016/j.annonc.2026.01.013

    Best Practices in GC-MS and GC × GC-MS-Based Metabolomics and Volatile Analyses: An International Survey.

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    Development of a Revised Clinical Guide to Multidimensional Needs Assessment in Palliative Care: MAP.

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    Breast cancer incidence, by stage at diagnosis, and mortality in 21 European countries in the era of mammography screening: an international population-based study.

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    Associations of the HER2DX Genomic Test with Biological and Pathologic Features in HER2-Positive Breast Cancer.

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    A Pilot Study Exploring Paraoxonase-1 Tissue Protein Expression and Circulating Levels in Bladder Cancer.

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    High leptin levels independent of body mass index are associated with inflammation and poorer treatment response in patients with diffuse large B-cell lymphoma.

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    Metabolomic-driven prediction of the mutational status of healthy individuals with a family history of hereditary breast and ovarian cancer syndrome: the HRRmet study.

    Roig B, Fernández-Castillejo S, Gumà J, Badia J, Melé M, Salvat M, Querol M, Cumeras R, Rodríguez-Balada M. 31/01/2026. Scientific Reports. 16. PMID: 41620477. doi: 10.1038/s41598-026-35789-8

    Liposomal irinotecan in patients with HER2-negative breast cancer and brain metastases: The PHENOMENAL phase 2 study.

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    Towards Breast Tumor Aggressiveness Classification in Digital Mammograms Using Boundary-Aware Segmentation and Feature Analysis

    Khalid, A, Mursil, M, Okran, AM, Padro, JG, Pablo, CL, Puig, D, Rashwan, HA. 01/01/2026. Medical Image Understanding And Analysis, Miua 2025, Pt Ii. 15917. doi: 10.1007/978-3-031-98691-8_12

    Circulating Lipid Profiles Indicate Incomplete Metabolic Recovery After Weight Loss, Suggesting the Need for Additional Interventions in Severe Obesity (vol 15, 1112, 2025)

    Onoiu, AI, Cambra-Cortés, V, Jiménez-Franco, A, Hernández-Aguilera, A, Parada, D, Riu, F, Zorzano, A, Camps, J, Joven, J. 25/12/2025. Biomolecules. 16. PMID: 41594720. doi: 10.3390/biom16010034

    SEOM-GOTEL clinical guidelines on diffuse large B-cell lymphoma (update 2025)

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    The impact of cancer survivors' extra risk of noncancer mortality on net survival estimation.

    Botta L, Capocaccia R, Bernasconi A, Rossi S, Galceran J, Dal Maso L, Lepage C, Molinié F, Bouvier AM, Marcos-Gragera R, Vener C, Guevara M, Murray D, Ragusa R, Gatta G, Jooste V. 04/11/2025. American Journal Of Epidemiology. 194. PMID: 40826891. doi: 10.1093/aje/kwaf148

    Trends in the incidence of brain cancer and the use of mobile phones: analysis of the Spanish Network of Cancer Registries (REDECAN)

    Galceran, J, Ameijide, A, Cañete, A, Peris-Bonet, R, de Munain, AL, Aizpurúa, A, de la Cruz, M, Sanvisens, A, Sánchez, MJ, Palacios, I, Franch, P, Sánchez, A, Guevara, M, Carulla, M, Gutiérrez, P, Sáez, I, Rodríguez, M, Alemán, A, Sabater, C. 01/11/2025. Clinical & Translational Oncology. 27. PMID: 40366608. doi: 10.1007/s12094-025-03932-y

    Performance and safety of Femorally Inserted Central Catheters in oncological patients: A cases series analysis

    Arrondo, MTP, Jurado, BG, Escat, LB, Ortiz-Miluy, G, Farrús, ICG, Gumà, J. 07/10/2025. Journal of Vascular Access. 27. PMID: 41058159. doi: 10.1177/11297298251375510

    Dysregulation of the FGF21-Adiponectin Axis in a Large Cohort of Patients with Severe Obesity and Liver Disease

    Castañé, H, Jiménez-Franco, A, Onoiu, AI, Cambra-Cortés, V, Hernández-Aguilera, A, Parada, D, Riu, F, Zorzano, A, Camps, J, Joven, J. 02/09/2025. International Journal Of Molecular Sciences. 26. PMID: 40943431. doi: 10.3390/ijms26178510

    IMPROVING THE COLORECTAL CANCER SCREENING PROGRAM WITH A BACTERIAL SIGNATURE IN THE PROTOCOL

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    Circulating Lipid Profiles Indicate Incomplete Metabolic Recovery After Weight Loss, Suggesting the Need for Additional Interventions in Severe Obesity

    Onoiu, AI, Cambra-Cortés, V, Jiménez-Franco, A, Hernández-Aguilera, A, Parada, D, Riu, F, Zorzano, A, Camps, J, Joven, J. 01/08/2025. Biomolecules. 15. PMID: 40867557. doi: 10.3390/biom15081112

    A population-based study of incidence trends of head and neck epithelial cancers in northeastern Spain, 1994-2018

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    Incidence trends of colorectal cancer in young adults in Spain

    Galceran, J. 29/07/2025. Clinical & Translational Oncology. 28. PMID: 40728704. doi: 10.1007/s12094-025-04006-9

    Effect of consumption of anthocyanin-rich products on NMR lipoprotein subclasses and biomarkers in hypercholesterolemic subjects: a randomized controlled trial (the AppleCOR study)

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    GcDUO: an open-source software for GC x GC-MS data analysis

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    Obesity and overweight in R/R DLBCL patients is associated with a better response to treatment of R2-GDP-GOTEL trial. Potential role of NK CD8 + cells and vitamin D.

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    Effectiveness and safety of first-line atezolizumab in locally advanced or metastatic urothelial cancer: The IMFLAME study.

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    Ketone Bodies Are Potential Prognostic Biomarkers in Relapsed/Refractory Diffuse Large B-Cell Lymphoma: Results from the R2-GDP-GOTEL Trial

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    Incidence and survival of rare adult solid cancers in Europe (EUROCARE-6): A population-based study

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    Multi-omics profiling reveals altered mitochondrial metabolism in adipose tissue from patients with metabolic dysfunction-associated steatohepatitis

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    PRIMARY PREVENTION OF BREAST CANCER THROUGH THE BRCAPP-ELISAH APP/WEB APPLICATION

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    Real-World Data of First-Line Cemiplimab Monotherapy for Metastatic Non-Small Cell Lung Cancer (NSCLC) with PD-L1 Expression = 50%: A National Spanish Multicentric Cohort (CEMI-SPA Study).

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    Epithelial head and neck cancer survival in Europe: Geographical variation, time trends and long term survival.

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    Efficacy of anti-PD1 therapy in PD1-high mRNA tumors across multiple cancer types: results from cohort 1 and cohort 2 of the phase II SOLTI-1904 ACROPOLI trial.

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    Effectiveness and Safety of Cabozantinib Treatment in Patients with Advanced Renal Cell Carcinoma in Spanish and Portuguese Real-world Practice: The SOGUG-SPRWEC Study.

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    Characterization of thrombosis risk in ambulatory patients with cancer: results of the observational, prospective, multicenter CARTAGO study.

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    Long-term survival and cure fraction estimates for paediatric central nervous system tumours in 31 European countries (EUROCARE-6): a population-based study.

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    Implementation of a clinical interview guide to Multidimensional needs assessment in Palliative care (MAP): A multicenter mixed-methods feasibility study.

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    An ambispective, real-world multi-center study of DOstarlimab in patients with Recurrent or Advanced DNA mismatch repair deficient/microsatellite instability-high endometrial cancer (GEICO 120-R/DORA study).

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    Prevalence of EGFR gene mutations in patients with early-stage resectable non-small cell lung cancer in Spain: the ORIGEN study.

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    Elacestrant in Women with Estrogen Receptor-Positive and HER2-Negative Early Breast Cancer: Results from the Preoperative Window-of-Opportunity ELIPSE Trial.

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    Dynamics of molecular heterogeneity in high-risk luminal breast cancer-From intrinsic to adaptive subtyping.

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    International benchmarking of stage at diagnosis for six childhood solid tumours (the BENCHISTA project): a population-based, retrospective cohort study.

    Botta L, Didonè F, Lopez-Cortes A, Nieto AC, Desandes E, Hjalgrim LL, Jakab Z, Stiller CA, Zeller B, Gatta G, Pritchard-Jones K. 01/02/2025. Lancet Child & Adolescent Health. 9. PMID: 39855760. doi: 10.1016/S2352-4642(24)00302-X

    Survivin/BIRC5 as a novel molecular effector at the crossroads of glucose metabolism and radioresistance in head and neck squamous cell carcinoma

    Benaiges, E, Ceperuelo-Mallafré, V, Guaita, S, Maymó-Masip, E, Madeira, A, Gómez, D, Hernández, V, Vilaseca, I, Merma, C, León, X, Terra, X, Vendrell, J, Avilés-Jurado, FX, Fernández-Veledo, S. 02/02/2024. Head And Neck-Journal For The Sciences And Specialties Of The Head And Neck. 46. PMID: 38305029. doi: 10.1002/hed.27651

    Metabolic adaptations in severe obesity: Insights from circulating oxylipins before and after weight loss

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    Socioeconomic inequalities in adherence to clinical practice guidelines and breast cancer survival: a multicentre population-based study in Spain

    Petrova, D, Redondo-Sánchez, D, Rodríguez-Barranco, M, Marcos-Gragera, R, Guevara, M, Carulla, M, de Munain, AL, Vizcaíno, A, del Barco, S, González-Flores, E, Pollán, M, Sánchez, MJ. 31/12/2024. BMJ Quality & Safety. PMID: 39740986. doi: 10.1136/bmjqs-2024-017809

    Ovarian Cancer Retrospective European (O'CaRE) study: first-line outcomes by number of risk factors for progression

    Krell, J, Shaw, D, McGrane, J, Hartkopf, A, Herrero, A, Yeoh, C, Masvidal, M, Raspagliesi, F, York, W, Schilder, JM, Mascialino, B, McDermott, E, Kalilani, L, Hanker, L. 22/12/2024. Future Oncology. 20. PMID: 39445504. doi: 10.1080/14796694.2024.2402217

    SpadaHC: a database to improve and homogenize the classification of variants in hereditary cancer genes in the Spanish population

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    SPME arrow-based extraction for enhanced targeted and untargeted urinary volatilomics

    Llambrich, M, Ramírez, N, Cumeras, R, Brezmes, J. 15/11/2024. Analytica Chimica Acta. 1329. PMID: 39396318. doi: 10.1016/j.aca.2024.343261

    Multiplatform metabolomic interlaboratory study of a whole human stool candidate reference material from omnivore and vegan donors

    Cruz, AK, Alves, MA, Andresson, T, Bayless, AL, Bloodsworth, KJ, Bowden, JA, Bullock, K, Burnet, MC, Neto, FC, Choy, A, Clish, CB, Couvillion, SP, Cumeras, R, Dailey, L, Dallmann, G, Davis, WC, Deik, AA, Dickens, AM, Djukovic, D, Dorrestein, PC, Eder, JG, Fiehn, O, Flores, R, Gika, H, Hagiwara, KA, Pham, TH, Harynuk, JJ, Aristizabal-Henao, JJ, Hoyt, DW, Jean-François, F, Kråkström, M, Kumar, A, Kyle, JE, Lamichhane, S, Li, Y, Nam, SL, Mandal, R, de la Mata, AP, Meehan, MJ, Meikopoulos, T, Metz, TO, Mouskeftara, T, Munoz, N, Gowda, GAN, Oresic, M, Panitchpakdi, M, Pierre-Hugues, S, Raftery, D, Rushing, B, Schock, T, Seifried, H, Servetas, S, Shen, T, Sumner, S, Carrillo, KST, Thibaut, D, Trejo, JB, Van Meulebroek, L, Vanhaecke, L, Virgiliou, C, Weldon, KC, Wishart, DS, Zhang, L, Zheng, JM, Da Silva, S. 04/11/2024. Metabolomics. 20. PMID: 39495321. doi: 10.1007/s11306-024-02185-0

    Metabolic profiling of tryptophan pathways: Implications for obesity and metabolic dysfunction-associated steatotic liver disease

    Arto, C, Rusu, EC, Clavero-Mestres, H, Barrientos-Riosalido, A, Bertran, L, Mahmoudian, R, Aguilar, C, Riesco, D, Chicote, JU, Parada, D, Martinez, S, Sabench, F, Richart, C, Auguet, T. 01/11/2024. European Journal Of Clinical Investigation. 54. PMID: 38940215. doi: 10.1111/eci.14279

    P25.03.B RWD OF IDH MUTANT GLIOMAS IN SPAIN, A RETSINE - GEINO STUDY

    Mazariegos, M, Girones, R, Del Barco, S, Garcia, A, Velilla, G, Hernandez, A, Alonso, M, Ferreira, L, Luque, N, Fernández,, Quintanar, T, Peralta, S, Ceballos,, Iza, E, Sanchez, M, Martín, EP, Casado, EA, Mazarico, J, Duran, G, Alvarez, P, Ayala, P, Gallego, O, Sarabia, R, de las Penas, R, Nuñez,, Morilla,, Cunquero, A, Cheverria, N, Moya,, Vaz, M, Luque, R, Esteve, A, Pineda, E. 17/10/2024. Neuro-Oncology. 26. doi: 10.1093/neuonc/noae144.446

    Artificial Intelligence Meets SCLC - Integrating Clinicopathological and Whole-Slide Image Data for Prognostic Prediction in SCLC.

    Rocha, P, Gibert, J, Menendez, S, del Rey-Vergara, R, Iñañez, A, Masfarre, L, Navarro, N, Rios-Hoyo, A, Perez, S, Taus, A, Giner, M, Rovira, A, León-Mateos, L, Isla, D, Paz-Ares, L, Zugazagoitia, J, Blanco, CM, García-Campelo, R, Moreno-Vega, A, Callejo, A, Rojo, F, Sanchez, I, Arriola, E. 01/10/2024. Journal Of Thoracic Oncology. 19

    Estimating cure and risk of death from other causes of cancer patients: EUROCARE-6 data on head & neck, colorectal, and breast cancers

    Botta, L, Capocaccia, R, Bernasconi, A, Rossi, S, Galceran, J, Dal Maso, L, Lepage, C, Molinié, F, Bouvier, AM, Marcos-Gragera, R, Vener, C, Guevara, M, Murray, D, Ragusa, R, Gatta, G, Jooste, V. 01/09/2024. European Journal Of Cancer. 208. PMID: 39013266. doi: 10.1016/j.ejca.2024.114187

    ABIGAIL: Randomized phase II study of abemaciclib plus endocrine therapy (ET) with or without a short course of induction paclitaxel in patients (pts) with previously untreated HR-positive/HER2-negative advanced breast cancer (HR+/HER2-ABC) with aggressive disease criteria

    Rodriguez, JD, Cortés, J, Di Cosimo, S, López-Barajas, IB, Castedo, SPC, López, A, López-Miranda, E, Juher, HP, Miro, CRA, Ponce, J, Ballerini, VC, Bouzas, LP, Arbizu, MV, Borrego, MRBR, Iranzo, V, Garrido, A, Alcalá-López, D, Mina, L, Mosquera, JJG, Cussac, AL. 01/09/2024. Annals Of Oncology. 35. doi: 10.1016/j.annonc.2024.08.2261

    Real-world data of IDH mutant gliomas in Spain, a RETSINE: GEINO study

    Mazariegos-Rubi, MA, Sarrió, RG, del Barco, S, Castano, AG, Velilla, G, Vinolas, MD, Garcia, MA, Freire, LF, Caro, NL, Perez, IF, Verduguez, TQ, Muñoz, SP, Lenza, IC, Rodriguez, EI, Sanfeliz, C, Martín, EP, Casado, EA, Mazarico, JM, Esteve, A, Pineda, E. 01/09/2024. Annals Of Oncology. 35. doi: 10.1016/j.annonc.2024.08.526

    Impact of coadministration of proton-pump inhibitors and palbociclib in hormone receptor-positive/HER2-negative advanced breast cancer

    Di Cosimo, S, Pérez-García, JM, Bellet, M, Dalenc, F, Gil, MJG, Ruiz-Borrego, M, Gavilá, J, Aguirre, E, Schmid, P, Marmé, F, Gligorov, J, Schneeweiss, A, Albanell, J, Zamora, P, Wheatley, D, de Dueñas, EM, Amillano, K, Shimizu, E, Sampayo-Cordero, M, Cortés, J, Llombart-Cussac, A. 01/08/2024. Breast. 76. PMID: 38880077. doi: 10.1016/j.breast.2024.103761

    First-line PARP inhibitor maintenance treatment in ovarian carcinoma for older adult women: a review of the current literature

    Hernandez, MM, Costa, SC, Coloma, CS, Cutillas, AQ, Barretina-Ginesta, MP, Sanchís, AC. 19/07/2024. Clinical & Translational Oncology. 27. PMID: 39030437. doi: 10.1007/s12094-024-03609-y

    Spatially Preserved Multi-Region Transcriptomic Subtyping and Biomarkers of Chemoimmunotherapy Outcome in Extensive-Stage Small Cell Lung Cancer

    Peressini, M, Garcia-Campelo, R, Massuti, B, Marti, C, Cobo, M, Gutiérrez, V, Dómine, M, Fuentes, J, Majem, M, de Castro, J, Córdoba, JF, Diz, MP, Isla, D, Esteban, E, Carcereny, E, Vila, L, Moreno-Vega, A, Ros, S, Moreno, A, García, FJ, Huidobro, G, Aguado, C, Cebey-López, V, Valdivia, J, Palmero, R, Lianes, P, López-Brea, M, Vidal, OJ, Provencio, M, Arriola, E, Baena, J, Herrera, M, Bote, H, Molero, M, Adradas, V, Ponce-Aix, S, Nuñez-Buiza, A, Ucero, A, Hernandez, S, Lopez-Rios, F, Conde, E, Paz-Ares, L, Zugazagoitia, J. 15/07/2024. Clinical Cancer Research. 30. PMID: 38630755. doi: 10.1158/1078-0432.CCR-24-0104

    SpadaHC: a database to improve the classification of variants in hereditary cancer genes in the Spanish population

    Moreno-Cabrera, JM, Feliubadaló, L, Pineda, M, Prada-Dacasa, P, Ramos-Muntada, M, Del Valle, J, Brunet, J, Gel, B, Currás-Freixes, M, Calsina, B, Salazar-Hidalgo, ME, Rodríguez-Balada, M, Roig, B, Fernández-Castillejo, S, Domínguez, MD, Ledo, MA, Sanz, MI, Castillejo, A, Dámaso, E, Soto, JL, de Miguel, M, Calero, BH, Sánchez-Zapardiel, JM, Ramon, T, Lasa, A, Gisbert-Beamud, A, López-Novo, A, Ruiz-Ponte, C, Potrony, M, Alvarez-Mora, M, Osorio, A, Lorda-Sánchez, I, Robledo, M, Cascon, A, Ruiz, A, Spataro, N, Hernan, I, Borràs, E, Moles-Fernández, A, Earl, J, Cadiñanos, J, Sánchez-Heras, AB, Bigas, A, Capellá, G, Lazaro, C. 04/07/2024. Database-The Journal of Biological Databases and Curation. 2024. PMID: 38965703. doi: 10.1093/database/baae055

    A red-fleshed apple rich in anthocyanins improves endothelial function, reduces inflammation, and modulates the immune system in hypercholesterolemic subjects: the AppleCOR study

    Pedret, A, Companys, J, Calderón-Pérez, L, Llauradó, E, Pla-Pagà, L, Salamanca, P, Sandoval-Ramírez, BA, Catalán, U, Fernández-Castillejo, S, Yuste, S, Macià, A, Gutiérrez-Tordera, L, Bulló, M, Camps, J, Canela, N, Valls, RM, Rubió-Piqué, L, Motilva, MJ, Solà, R. 04/06/2024. Food & Function. 15. PMID: 38751340. doi: 10.1039/d3fo05114e

    Primary results from PATRICIA cohort C (SOLTI-1303), a randomized phase II study evaluating palbociclib with trastuzumab and endocrine therapy in pretreated HER2-positive and PAM50 luminal advanced breast cancer

    Ciruelos, E, Pascual, T, Villacampa, G, Pernas, S, Sanchez-Bayona, R, Ponce-Lorenzo, JJ, de Ibarguren, BCS, Escrivá-de-Romaní, S, Perello, A, Montaño, A, Martinez, E, González, AL, Olivé, MM, De La Haba, J, Cortes, J, Oliveira, M, Villanueva, L, Gonzalez, X, Villagrasa, P, Prat, A. 01/06/2024. Journal Of Clinical Oncology. 42

    Exploring management and outcomes of elderly patients with glioblastoma using data from two randomised trials (GEINO1401/EX-TEM)

    Gately, L, Mesía, C, Sepúlveda, JM, del Barco, S, Pineda, E, Gironés, R, Fuster, J, Dumas, M, Gill, S, Navarro, LM, Herrero, A, Dowling, A, de las Peñas, R, Vaz, MA, Alonso, M, Lwin, Z, Harrup, R, Peralta, S, Long, A, Perez-Segura, P, Ahern, E, Garate, CO, Wong, M, Campbell, R, Cuff, K, Jennens, R, Gallego, O, Underhill, C, Martinez-Garcia, M, Covela, M, Cooper, A, Brown, S, Rosenthal, M, Torres, J, Collins, IM, Gibbs, P, Balana, C. 01/06/2024. Journal Of Neuro-Oncology. 168. PMID: 38630385. doi: 10.1007/s11060-024-04668-5

    Validation of prognostic and predictive value of total tumoral load after primary systemic therapy in breast cancer using OSNA assay

    Bernet-Vegué, L, Cantero-González, C, de Salas, MS, Parada, D, Perin, T, Quintero-Niño, Z, Pérez-Quintela, BV, Sánchez-Guzman, D, Castelvetere, M, Hernaez, DH, Martín-Salvago, MD. 01/05/2024. Clinical & Translational Oncology. 26. PMID: 38070048. doi: 10.1007/s12094-023-03347-7

    Changes in oxidative stress and the inflammatory system in breast cancer patients

    Avila, VDC, Franco, AJ, Capdevila, MC, Pablo, RG, Aguilar, JMJ, Casta , H, Mora, PA, Chac n, BAM, Benitez, G, Acosta, JC, Benavides, R, Troncho, CE, Engel, O, Parada, D, De la Flor, M, Jord , C, Mel , M, Repkova, J, Prat, MA. 01/05/2024. Radiotherapy And Oncology. 194

    Metabolic profiling of plasma and tissue in breast cancer patients: uncovering therapeutic response

    Jim nez-Franco, A, Calder n, D, Jim nez-Aguilar, J, Canela-Capdevila, M, Garc a-Pablo, R, Casta , H, Araguas, P, Malave, B, Acosta, JC, Benavides, R, Arquez, M, Casta o, F, Riu, F, De la Flor, M, Jord , C, Mel , M, Repkova, J, Amillano, K, Camps, J, Joven, J, Arenas, M. 01/05/2024. Radiotherapy And Oncology. 194

    Optimal [18F]FDG PET/CT Cutoff for Pathologic Complete Response in HER2-Positive Early Breast Cancer Patients Treated with Neoadjuvant Trastuzumab and Pertuzumab in the PHERGain Trial

    Gebhart, G, Keyaerts, M, Guiot, T, Flamen, P, Ruiz-Borrego, M, Stradella, A, Bermejo, B, Escriva-de-Romani, S, Martínez, LC, Ribelles, N, Fernandez-Abad, M, Albacar, C, Colleoni, M, Garrigos, L, de Frutos, MA, Dalenc, F, Prat, A, Marmé, F, Schmid, P, Kerrou, K, Braga, S, Gener, P, Sampayo-Cordero, M, Cortés, J, Pérez-García, JM, Llombart-Cussac, A. 01/05/2024. Journal Of Nuclear Medicine. 65. PMID: 38575192. doi: 10.2967/jnumed.123.266384

    3-year invasive disease-free survival with chemotherapy de-escalation using an 18F-FDG-PET-based, pathological complete response-adapted strategy in HER2-positive early breast cancer (PHERGain): a randomised, open-label, phase 2 trial

    Pérez-García, JM, Cortés, J, Ruiz-Borrego, M, Colleoni, M, Stradella, A, Bermejo, B, Dalenc, F, Escrivá-de-Romaní, S, Martínez, LC, Ribelles, N, Marmé, F, Cortés, A, Albacar, C, Gebhart, G, Prat, A, Kerrou, K, Schmid, P, Braga, S, Di Cosimo, S, Gion, M, Antonarelli, G, Popa, C, Szostak, E, Alcalá-López, D, Gener, P, Rodríguez-Morató, J, Mina, L, Sampayo-Cordero, M, Llombart-Cussac, A. 27/04/2024. Lancet. 403. PMID: 38582092. doi: 10.1016/S0140-6736(24)00054-0

    Prevalence of Homologous Recombination Deficiency Among Patients With Germline RAD51C/D Breast or Ovarian Cancer

    Torres-Esquius, S, Llop-Guevara, A, Gutiérrez-Enríquez, S, Romey, M, Teulé, A, Llort, G, Herrero, A, Sánchez-Henarejos, P, Vallmajó, A, González-Santiago, S, Chirivella, I, Cano, JM, Graña, B, Simonetti, S, de Corcuera, ID, Cajal, TRY, Sanz, J, Serrano, S, Otero, A, Churruca, C, Sánchez-Heras, AB, Servitja, S, Guillén-Ponce, C, Brunet, J, Denkert, C, Serra, V, Balmaña, J. 22/04/2024. Jama Network Open. 7. PMID: 38648056. doi: 10.1001/jamanetworkopen.2024.7811

    Easy-Amanida: An R Shiny application for the meta-analysis of aggregate results in clinical metabolomics using Amanida and Webchem

    Llambrich, M, Satorra, P, Correig, E, Gumà, J, Brezmes, J, Tebé, C, Cumeras, R. 13/03/2024. Research Synthesis Methods. 15. PMID: 38480474. doi: 10.1002/jrsm.1713

    A Descriptive Study of 103 Primary Cutaneous B-Cell Lymphomas: Clinical and Pathological Characteristics and Treatment from the Spanish Lymphoma Oncology Group (GOTEL)

    Martínez-Banaclocha, N, Martínez-Madueño, F, Caballé, B, Badia, J, Blanes, M, Bujanda, DA, Calvo, V, Codina, JG, Blanco, CQ, Espinosa, P, Lavernia, J, Arroyo, FRG, Risueño, MG, Llorca, C, Cumeras, R, Pulla, MP, Gumà, J. 01/03/2024. Cancers. 16. PMID: 38473391. doi: 10.3390/cancers16051034

    Influence of chemotherapy regimens prior to nivolumab on the survival of recurrent/metastatic SCCHN.

    Blanco, CM, Palomares, LD, Gonzálvez, CL, Muñoz, SP, Laguna, VM, Llansa, LA, Gómez, DG, Mejía, MM, Pinel, MA, Linares, CM, Padró, JG. 01/03/2024. Radiotherapy And Oncology. 192

    Adherence to clinical practice guidelines: a population-based study of socio-economic inequalities in breast cancer

    Petrova, D, Sánchez, DR, Rodríguez-Barranco, M, Carulla, M, Guevara, M, de Munain, AL, Vizcaíno, A, Marcos-Gragera, R, González-Flores, E, Sant, M, Pollán, M, Sánchez-Pérez, MJ. 01/03/2024. European Journal Of Cancer. 200. doi: 10.1016/j.ejca.2024.113827

    CD8+NKs as a potential biomarker of complete response and survival with lenalidomide plus R-GDP in the R2-GDP-GOTEL trial in recurrent/refractory diffuse large B cell lymphoma

    Hontecillas-Prieto, L, García-Domínguez, DJ, Palazón-Carrión, N, García-Sancho, AM, Nogales-Fernández, E, Jiménez-Cortegana, C, Sánchez-León, ML, Silva-Romeiro, S, Flores-Campos, R, Carnicero-González, F, Ríos-Herranz, E, de la Cruz-vicente, F, Rodríguez-García, G, Fernández-Alvarez, R, Martínez-Banaclocha, N, Gumà-Padrò, J, Gómez-Codina, J, Salar-Silvestre, A, Rodríguez-Abreu, D, Gálvez-Carvajal, L, Labrador, J, Guirado-Risueño, M, Provencio-Pulla, M, Sánchez-Beato, M, Marylene, L, Alvaro-Naranjo, T, Casanova-Espinosa, M, Rueda-Domínguez, A, Sánchez-Margalet, V, de la Cruz-merino, L. 26/02/2024. Frontiers in immunology. 15. PMID: 38469299. doi: 10.3389/fimmu.2024.1293931

    Atypical Presentation of an Ovarian Yolk Sac Tumor in an 80-Year-Old Woman: A Case Report and Review of the Literature

    Maldonado, V, Masvidal, M, Laguna, VM, Cimerman, J, Soriano, SM. 01/01/2024. Case Reports in Oncology. 17. PMID: 39628710. doi: 10.1159/000542244

    Current Practices in LC-MS Untargeted Metabolomics: A Scoping Review on the Use of Pooled Quality Control Samples.

    Broeckling CD, Beger RD, Cheng LL, Cumeras R, Cuthbertson DJ, Dasari S, Davis WC, Dunn WB, Evans AM, Fernández-Ochoa A, Gika H, Goodacre R, Goodman KD, Gouveia GJ, Hsu PC, Kirwan JA, Kodra D, Kuligowski J, Lan RS, Monge ME, Moussa LW, Nair SG, Reisdorph N, Sherrod SD, Ulmer Holland C, Vuckovic D, Yu LR, Zhang B, Theodoridis G, Mosley JD. 26/12/2023. Analytical Chemistry. 95. PMID: 38055671. doi: 10.1021/acs.analchem.3c02924

    Childhood and Adolescent Central Nervous System Tumours in Spain: Incidence and Survival over 20 Years: A Historical Baseline for Current Assessment.

    Chirlaque MD, Peris-Bonet R, Sánchez A, Cruz O, Marcos-Gragera R, Gutiérrez-Ávila G, Quirós-García JR, Almela-Vich F, López de Munain A, Sánchez MJ, Franch-Sureda P, Ardanaz E, Galceran J, Martos C, Salmerón D, Gatta G, Botta L, Cañete A, The Spanish Childhood Cancer Epidemiology Working Group. 18/12/2023. Cancers. 15. PMID: 38136432. doi: 10.3390/cancers15245889

    A Metabolites Merging Strategy (MMS): Harmonization to Enable Studies' Intercomparison.

    Villalba H, Llambrich M, Gumà J, Brezmes J, Cumeras R. 21/11/2023. Metabolites. 13. PMID: 38132849. doi: 10.3390/metabo13121167

    SEOM-GOTEL clinical guidelines on diffuse large B cell lymphoma (2022)

    Gumà, J, Palazón-Carrión, N, Rueda-Domínguez, A, Sequero, S, Calvo, V, García-Arroyo, R, Gómez-Codina, J, Llanos, M, Martínez-Banaclocha, N, Provencio, M. 01/09/2023. Clinical & Translational Oncology. 25. PMID: 37289353. doi: 10.1007/s12094-023-03206-5

    Opportunistic genetic screening increases the diagnostic yield and is medically valuable for care of patients and their relatives with hereditary cancer

    Fernández-Castillejo, S, Roig, B, Melé, M, Serrano, S, Salvat, M, Querol, M, Brunet, J, Pineda, M, Cisneros, A, Parada, D, Badia, J, Borràs, J, Rodríguez-Balada, M, Gumà, J. 17/08/2023. Journal Of Medical Genetics. 61. PMID: 37591735. doi: 10.1136/jmg-2023-109389

    Blood Liquid Biopsy in an Advanced Medullary Thyroid Carcinoma: A Case Study with Rearranged during Transfection Heterogeneity

    Gumà, J, Peña, KB, Riu, F, Lucia-Gozálvez, C, Vidaller, A, Maldonado, V, Parada, D. 01/08/2023. Pathobiology. 90. PMID: 36731433. doi: 10.1159/000527184

    Differences in the Stool Metabolome between Vegans and Omnivores: Analyzing the NIST Stool Reference Material

    Cumeras, R, Shen, T, Valdiviez, L, Tippins, Z, Haffner, B, Fiehn, O. 01/08/2023. Metabolites. 13. PMID: 37623865. doi: 10.3390/metabo13080921

    Incidence and time trends of childhood hematological neoplasms: a 36-year population-based study in the southern European context, 1983-2018

    Trallero, J, Sanvisens, A, Vich, FA, El Karoni, NJ, Lloret, IS, Díaz-del-Campo, C, Marcos-Navarro, AI, Atxega, AA, Uriarte, PS, Ortega, MD, Sánchez, MJ, Perucha, J, Franch, P, Chirlaque, MD, Guevara, M, Ameijide, A, Galceran, J, Ramírez, C, Camblor, MR, Alemán, MA, Gutiérrez, P, Marcos-Gragera, R. 25/07/2023. Frontiers in oncology. 13. PMID: 37560466. doi: 10.3389/fonc.2023.1197850

    Study of Liquid-Based Cytology Using Next-Generation Sequencing as a Liquid Biopsy Application in Patients with Advanced Oncological Disease

    Peña, KB, Riu, F, Hernandez, A, Guilarte, C, Elizalde-Horcada, M, Parada, D. 01/06/2023. Biomedicines. 11. PMID: 37371673. doi: 10.3390/biomedicines11061578

    Exploring the circulatory metabolic alterations in breast cancer patients

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    SUCNR1 signaling in adipocytes controls energy metabolism by modulating circadian clock and leptin expression

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    Retrospective Analysis of Vaccination Status and Predominant Viral Variants in Patients Hospitalized with COVID-19 in Reus, Spain

    Iftimie, S, López-Azcona, AF, Lozano-Olmo, MJ, Naval-Ferrando, A, Domingo-Cortés, V, Castañé, H, Jiménez-Franco, A, Hernández-Aguilera, A, Guilarte, C, Riu, F, Camps, J, Joven, J, Castro, A. 01/04/2023. Viruses-Basel. 15. PMID: 37112865. doi: 10.3390/v15040886

    SARS-CoV-2 Serum Viral Load and Prognostic Markers Proposal for COVID-19 Pneumonia in Low-Dose Radiation Therapy Treated Patients

    Piqué, B, Peña, K, Riu, F, Acosta, JC, Torres-Royo, L, Malave, B, Araguas, P, Benavides, R, De Febrer, G, Camps, J, Joven, J, Arenas, M, Parada, D. 01/02/2023. Journal of clinical medicine. 12. PMID: 36769445. doi: 10.3390/jcm12030798

    Increased Hepatic ATG7 mRNA and ATG7 Protein Expression in Nonalcoholic Steatohepatitis Associated with Obesity

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    Monitoring of Circulating Tumor DNA Predicts Response to Treatment and Early Progression in Follicular Lymphoma: Results of a Prospective Pilot Study

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    GCIMS: An R package for untargeted gas chromatography - Ion mobility spectrometry data processing

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    Matrix Metalloproteinase-9 Expression Is Associated with the Absence of Response to Neoadjuvant Chemotherapy in Triple-Negative Breast Cancer Patients

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    Cancer Survival in Adults in Spain: A Population-Based Study of the Spanish Network of Cancer Registries (REDECAN)

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    Incidence of myeloid neoplasms in Spain (2002-2013): a population-based study of the Spanish network of cancer registries

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    Mammographic features of benign breast lesions and risk of subsequent breast cancer in women attending breast cancer screening

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    Prospective evaluation of the prognostic value of circulating tumor DNA in patients with follicular lymphoma: A pilot study.

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    Efficacy and safety of atezolizumab concurrent with radiotherapy in patients with muscle-invasive bladder cancer: An interim analysis of the ATEZOBLADDERPRESERVE phase II trial (SOGUG-2017-A-IEC(VEJ)-4).

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    Using population-based data to evaluate the impact of adherence to endocrine therapy on survival in breast cancer through the web-application BreCanSurvPred

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    Estimates of the incidence of hematological neoplasms in Spain, 2021: Study of the Spanish Network of Cancer Registries (REDECAN)

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    No Excess Mortality up to 10 Years in Early Stages of Breast Cancer in Women Adherent to Oral Endocrine Therapy: A Probabilistic Graphical Modeling Approach

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    Predicting Ovarian-Cancer Burden in Catalonia by 2030: An Age-Period-Cohort Modelling

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