Presentació dels Hospitals
Col·labora

Autoimmunitat, Infecció i Trombosi (GRAIÏT)

INFECCIÓ, IMMUNITAT I MEDI AMBIENT
SEPSIS MALALTIES INFECCIOSES TOXICOLOGIA MICROBIOLOGIA
OBJECTIUS

El grup GRAIÏT està format per un equip multidisciplinari de metges, amb una important experiència clínica, activitat docent i investigadora (8 doctors i 5 predoctorants). Treballa conjuntament per ampliar el coneixement de les malalties autoimmunes i infeccioses. El principal camp de recerca se centra en l’estudi de les bases fisiopatògenes d’aquestes malalties amb l’objectiu d’identificar nous biomarcadors i possibles dianes terapèutiques.

A més, aquestes malalties comparteixen elements relacionats amb un estat d’inflamació crònica que condueix al desenvolupament d’alteracions metabòliques, risc cardiovascular i esdeveniments trombòtics que marquen el pronòstic i la morbiditat i mortalitat d’aquests pacients.

Des del 2020, GRAIÏT també se centra en la recerca de biomarcadors pronòstics i dianes terapèutiques en COVID-19 i símptomes persistents (post-COVID).

RESPONSABLES

  • Dr. Antoni Castro Salomó

  • Dra. Sandra Parra Pérez

  • Línies de recerca
  • PROJECTES COMPETITIUS
  • PROJECTES NO COMPETITUS FINANCIATS EN ELS ÚLTIMS ANYS
  • Membres del grup
  • TESIS DOCTORALS
  • RELEVÀNCIA PER A COMITÉS ASESORS I/O MEMBRES O GRUPS D'EXPERTS DE SOCIETATS CIENTÍFIQUES I/O ÒRGANS OFICIALS
  • Publicacions
  • Contacte
  • Estudi del risc cardiovascular i arteriosclerosi subclínica en pacients amb Lupus Eritematós Sistèmic (LES)
  • Investigació de marcadors d’aterosclerosi subclínic en pacients amb LES (grossor íntima-mitjana de la caròtida, funció endotelial i rigidesa arterial)
  • Estudi lipidòmic i proteòmic de les lipoproteïnes en pacients amb LES
  • Investigació de biomarcadors d’activitat en pacients amb LES (Gelsolin)
  • Estudi dels marcadors pronòstics d’infeccions associades al catèter i d’infeccions del sistema sanitari
  • Estudi de nous biomarcadors pronòstics en pacients ingressats per pneumònia adquirida a la comunitat (PAC) i per COVID-19. SIGLES NAC-HDL COVID-19
  • Gelsolina: biomarcador i potencial tractament per al pacient post-Covid
  • Marcadors pronòstics i risc cardiovascular en pacients amb Malalties autoimmunes sistèmiques
  • Marcadors pronòstics en pacients ingressats a UCI per sepsis
  • Risc cardiovascular y marcadors pronòstics en hipertensió arterial

  • FUNDACIÓ MARATÓ TV3 IDENTIFICATION OF BIOMARKERS NASED ON ENERGY METABOLISM AND OXIDATIVE STRESS IN PATIENTS WITH URINARY CATHETER-ASSOCIATED INFECTIONS AND DEVELOPMENT OF BIOSENSORS FOR THEIR DETEMRINATION IN PRIMARY AND HOSPITAL CARE . J CAMPS. (FUNDACIÓ PRIVADA INVESTIGACIONS SANITARIES PERE VIRGILI). 6/3/18-18/6/21. 197.000

  • Beca de Recerca Bàsica 2016 de l’Acadèmia de Ciències Mèdiques i de la Salut de Catalunya i de Balears, pel projecte Efectivitat d’un Smartwatch en l’activació del circuit de Reanimació Cardiopulmonar en pacients amb aturada cardiorespiratòria al carrer. Acadèmia de les Ciències Mèdiques de Catalunya i Balears. Josep Basorar et al. (Institut Català de la Salut) Des de 2016-actualitat. 20.000 euros.

  • SAL-OSTEOP-2010-01 (ESTUDIO FRATER) “Utilidad de la herramienta FRAX para predecir el riesgo de fractura en pacientesatendidos en consultas de reumatología en España”.

  • ROC-TOC-2011-01 (ACT-AXIS) “Estudio observacional, prospectivo, para evaluar y correlacionar el impacto del tratamiento con RoActemra® (Tocilizumab) sobre la fatiga y diferentes factores que influyen en ella en pacientes con artritis reumatoide en la práctica clínica habitual.Estudio ACT-A”

  • ABB-LOP-2010-01“Percepción del tratamiento con Kaletra (comprimidos) dosificado 1 vez al día en PacientesInfectados por VIH. Estudio TransversAL (QD-KAPITAL)”. (FINALITZAT 2012)

  • ORDI-01” Ensayo clínico aleatorizado y controlado para evaluar la eficacia de la azatioprina vs. micofenolatosódico para el tratamiento de la fase de inducción y mantenimiento de la remisión de los brotes extra renales del lupus eritematoso”.

  • NOV-ANT-2011-01“Prevalencia y manejo clínico de pacienteshospitalizadosinfectados por grampositivos con insuficiencia renal en España. Estudio Daptokidney: Fases Prevenir y Evaluar.” (ESTUDIO DAPTOKIDNEY)

  • ESTUDIO SEQUENCE “Oportunidades de secuenciación intravenosa a oral y de alta precoz en infecciones por grampositivos que precisan de tratamiento con un glucopéptido o lipopéptido”.

  • BAY-RIV-2012-01 ” XALIA Xarelto© para la Anticoagulación a Largo plazo e Inicial en el tromboembolismo venoso (TEV) “.

  • SHI-TSE-2011-01 “Estudio epidemiológico sobre el estado actual de los pacientes con enfermedad de Gaucher tipo I en España, evaluados mediante la TherapeuticGoals MAP (Monitor, ActionandProgress) Tool© “. Estudio MAPPING EG.

  • SAP-02 “rivaroxaban versus acenocumarol en la profilaxis secundaria del síndrome  tifosfolípido: un estudio multicéntrico, prospectivo y randomizado. análisis de factores de estratificaciónpronóstica de evolución clínica.”

  • BMS-ACO-2014-01 ESTUDIO PERFILAR:“Estudio multicéntrico observacional para determinar el perfil y manejo del tratamiento antitrombótico de los pacientes con fibrilación auricular no valvular que acuden a los servicios de medicina interna de los hospitales españoles” Código CV185372

  • CE01-301: Study drug Solthromycin . CEM-101 A Randomized, Double – Blind, Multi -Center Study to Evaluate the Efficacy and Safety of Intravenous to Oral Solithromycin (CEM -101) Compared to Intravenous to Oral Moxifloxacin in the Treatment of Adult Patients with Community -Acquired Bacterial Pneumonia

  • LCD-CDAD-10-07/11-06 A Randomized, Double-Blinded, Active-Controlled Study of CB-183, 315 in Patients with Clostridium Difficile Associated Diarrea. Cubist Pharmaceuticals.

  • Títol del projecte: Arteriosclerosis subclínica en pacientes con enfermedades sistémicas. Colección de muestras biológicas y estudio vascular en pacientes con LES en el momento inicial, a los 3 años de seguimiento y en brote clínico. IP: Antoni Castro. Inici 2006-vigent

  • TÍTOL DEL PROJECTE: (NAC-HDL) Relación entre los factores pronósticos de los pacientes ingresados por neumonía adquirida en la comunidad (NAC) y el estudio de funcionalidad y composición de las partículas de colesterol HDL IP: Sandra Parra, Antoni Castro 2012-vigent

  • ESTUDI FASE III, ALEOATORITZAT, AMB DOBLE ENMASCARAMENT I COMPRADOR ACTIU DE LA EFICACIA I LA SEGURETAT ENTRE RIDINILAZOL (200mg, 2 C/dia) DURANTE 10 DIAS I VANCOMICINA (125 mg, 4 cops/dia) DURANT 10 DIES PER AL TRACTAMENT DE LA INFECCIÓ PER CLOSTRIDIUM DIFFICILE (ICD). Antoni Castro Salomó. 15/10/2019-15/10/2022) 10.524 Euros.

  • A Phase 2 Randomized, Double-Blind, Placebo-Controlled, Proof-of-Concept study to evaluate the Efficacy and Safety of Recombinant Human Plasma Gelsolin (rhu-pGSN) added to Standard of Care for Treatment of Subjects with Severe COVID-19 Pneumonia. BIoaegis. IP: Antoni Castro, Co_IP: Sandra parra 1/8/2020-1/8/2021. 180.000 euros.

  • Doctorand: Mireia Saballs Nadal

    Títol: Importància clínica dels nivells de colesterol HDL en l’evolució i l’aparició de complicacions en la pneumònia adquirida a la comunitat i la COVID-19.

    Any de defensa i calificació: 01/04/2025, Cum laude

    Supervisors: Antoni Castro Salomó, Sandra Parra  Pérez

  • Doctorant: Marta González

    Títol: Alterations in the metabolsim of tryglicerides in Systemic Lupus Erythematosus.

    Any de defensa i calificació: 2016, Cum Laude.

    Supervisors: Antoni Castro i Josep Rivalta, Universitat Rovira i Virgili.

  • Doctorant: Miguel Camafort Babkowski

    Títol: Artherial pressure ambulatory monitoring utility in the prognostic of patients with heart failure.

    Any de defensa i calificació: 2016, Distinction.

    Supervisor: Antoni Castro, Universitat Rovira i Virgili.

  • Doctorant: Simona Micaela Iftime

    Títol: Paraoxonase-1 in patients with catheter associated infections

    Any de defensa i calificació: 2015, Cum Laude.

    Supervisor: Antoni Castro, Universitat Rovira i Virgili.

  • Grupo de Enfermedades Autoinmunes Sistémicas (GEAS-SEMI). Sociedad Española de Medicina Interna (Antoni Castro Salomó, Sandra Parra Pérez)
  • Línea de investigación Esclerodermia-REMSCLE (Antoni Castro Salomó, Sandra Parra Pérez)
  • Registro Español de pacientes con Lupus Eritematoso Sitémico (RELES)
  • Registro Español de pacientes tratados con Belilumab (BeliLESGEAS)
  • Estudio EPINE. Estudio de prevalencia de la infección nosocomial en España

    Año

    Assessment of physical status and analysis of lipidomic and metabolomic alterations in patients with Post-COVID-19 condition.

    Pavón R, Parra S, Rubio FJ, Feliu M, Ríos M, Iftimie S, Rovira C, Amigó N, Cabau L, Martínez-Micaelo N, Castro A. 03/03/2026. Plos One. 21. PMID: 41774679. doi: 10.1371/journal.pone.0341192

    Subphenotype- and complication-guided adjunctive fosfomycin versus standard monotherapy in Staphylococcus aureus bacteraemia: pooled analysis of two randomised trials.

    Escrihuela-Vidal F, Larrauri JG, López-Contreras J, Euba G, Vázquez A, Gómez-Zorrilla S, López-Cortés LE, Gasch O, Aparicio-Minguijón E, Escudero-Sánchez R, Pérez-Rodríguez MT, Rodríguez-Pardo D, Jover-Sáenz A, García-Pardo G, Rodríguez-Baño J, Pujol M, Carratalà J, Gutiérrez-Gutiérrez B. 01/03/2026. Lancet Regional Health-Europe. 62. PMID: 41788427. doi: 10.1016/j.lanepe.2026.101611

    Post-Radiotherapy Changes in Circulating Dodecanoic Acid Identify Metabolic Phenotypes Associated with Recurrence in Breast Cancer.

    Jiménez-Franco A, Cambra-Cortés V, García-Pablo R, Canela-Capdevila M, Benavides-Villarreal R, Gabaldó-Barrios X, Fort-Gallifa I, Camps J, Joven J, Arenas M. 26/02/2026. Biomolecules. 16. PMID: 41897292. doi: 10.3390/biom16030355

    A Pilot Study Exploring Paraoxonase-1 Tissue Protein Expression and Circulating Levels in Bladder Cancer.

    Parada D, Onoiu AI, Iftimie S, Camps J, Riu F, Castro A, Joven J. 02/02/2026. Antioxidants. 15. PMID: 41750579. doi: 10.3390/antiox15020198

    ERG expression is not predictive of outcome in patients with intermediate- and high-risk localized prostate cancer treated with combined androgen blockade and radiotherapy

    Henriquez, I, Malave, B, Benitez-Gabella, G, Parada, D, Canela, M, García-Pablo, R, Benavides, R, Rius, F, Arenas, M. 01/02/2026. Clinical & Translational Oncology. 28. PMID: 40788562. doi: 10.1007/s12094-025-04016-7

    Insights into the diagnostic and prognostic value of paraoxonase 1-related variables and inflammatory markers in community-acquired pneumonia (Vol 418, 111606, 2025)

    Ballester, F, Gabaldo-Barrios, X, Pujol, I, Iftimie, S, Camps, J, Parra, S, Castro, A, Joven, J. 05/01/2026. Chemico-Biological Interactions. 423. PMID: 41207078. doi: 10.1016/j.cbi.2025.111808

    Circulating Lipid Profiles Indicate Incomplete Metabolic Recovery After Weight Loss, Suggesting the Need for Additional Interventions in Severe Obesity (vol 15, 1112, 2025)

    Onoiu, AI, Cambra-Cortés, V, Jiménez-Franco, A, Hernández-Aguilera, A, Parada, D, Riu, F, Zorzano, A, Camps, J, Joven, J. 25/12/2025. Biomolecules. 16. PMID: 41594720. doi: 10.3390/biom16010034

    Insights into the diagnostic and prognostic value of paraoxonase 1-related variables and inflammatory markers in community-acquired pneumonia

    Ballester, F, Gabaldó-Barrios, X, Jiménez-Franco, A, Pujol, I, Iftimie, S, Camps, J, Parra, S, Castro, A, Joven, J. 05/09/2025. Chemico-Biological Interactions. 418. PMID: 40516592. doi: 10.1016/j.cbi.2025.111606

    Dysregulation of the FGF21-Adiponectin Axis in a Large Cohort of Patients with Severe Obesity and Liver Disease

    Castañé, H, Jiménez-Franco, A, Onoiu, AI, Cambra-Cortés, V, Hernández-Aguilera, A, Parada, D, Riu, F, Zorzano, A, Camps, J, Joven, J. 02/09/2025. International Journal Of Molecular Sciences. 26. PMID: 40943431. doi: 10.3390/ijms26178510

    Circulating Lipid Profiles Indicate Incomplete Metabolic Recovery After Weight Loss, Suggesting the Need for Additional Interventions in Severe Obesity

    Onoiu, AI, Cambra-Cortés, V, Jiménez-Franco, A, Hernández-Aguilera, A, Parada, D, Riu, F, Zorzano, A, Camps, J, Joven, J. 01/08/2025. Biomolecules. 15. PMID: 40867557. doi: 10.3390/biom15081112

    Metabolic Reprogramming in Respiratory Viral Infections: A Focus on SARS-CoV-2, Influenza, and Respiratory Syncytial Virus

    Camps, J, Iftimie, S, Jimenez-Franco, A, Castro, A, Joven, J. 16/07/2025. Biomolecules. 15. PMID: 40723899. doi: 10.3390/biom15071027

    Serum butyrylcholinesterase activity as a predictor of severity and mortality in COVID-19 patients

    Fazekas, T, Kovaik, L, Rad, MM, Barrios, XG, Iftimie, SM, Camps, J, Hrabovská, A. 02/07/2025. Scientific Reports. 15. PMID: 40604014. doi: 10.1038/s41598-025-07017-2

    Jordans' anomaly in Chanarin-Dorfman syndrome

    Sánchez-Cortés, J, Gabaldó-Barrios, X. 28/03/2025. Advances In Laboratory Medicine-Avances En Medicina De Laboratorio. 6. PMID: 40160390. doi: 10.1515/almed-2024-0159

    Oral antibiotic prophylaxis induces changes in the microbiology of surgical site infection after colorectal surgery. A matched comparative study.

    Flores-Yelamos M, Juvany M, Badia JM, Vázquez A, Pascual M, Parés D, Almendral A, Limón E, Pujol M, Gomila-Grange A. 01/02/2025. Colorectal Disease. 27. PMID: 39887585. doi: 10.1111/codi.70008

    Evaluating the use of Uromune® autovaccine in recurrent urinary tract infections: a pilot unicenter retrospective study in Reus, Spain

    Iftimie, S, Ladero-Palacio, P, López-Azcona, AF, Pujol-Galarza, L, Pont-Salvadó, A, Gabaldó-Barrios, X, Joven, J, Camps, J, Castro, A, Pascual-Queralt, M. 24/01/2025. Bmc Infectious Diseases. 25. PMID: 39856603. doi: 10.1186/s12879-025-10524-2

    Multi-omics profiling reveals altered mitochondrial metabolism in adipose tissue from patients with metabolic dysfunction-associated steatohepatitis

    Castañé, H, Jiménez-Franco, A, Hernández-Aguilera, A, Martínez-Navidad, C, Cambra-Cortés, V, Onoiu, AI, Jiménez-Aguilar, JM, Paris, M, Hernández, M, Parada, D, Guilarte, C, Zorzano, A, Hernández-Alvarez, MI, Camps, J, Joven, J. 01/01/2025. EBioMedicine. 111. PMID: 39731853. doi: 10.1016/j.ebiom.2024.105532

    The Lipoprotein Profile Evaluated by 1H-NMR Improves the Performance of Genetic Testing in Familial Hypercholesterolemia

    Daiana, I, Didac, L, Celia, RB, Natalia, A, Nuria, P, Roberto, S, Ana, GL, Nuria, A, Josefa, G, Lluis, M. 23/01/2024. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 109. PMID: 38262691. doi: 10.1210/clinem/dgae037

    Inclisiran, Reasons for a Novel Agent in a Crowded Therapeutic Field

    Di Giacomo-Barbagallo, F, Andreychuk, N, Scicali, R, Gonzalez-Lleo, A, Piro, S, Masana, L, Ibarretxe, D. 01/12/2024. Current Atherosclerosis Reports. 27. PMID: 39786678. doi: 10.1007/s11883-024-01271-x

    Metabolic profiling of tryptophan pathways: Implications for obesity and metabolic dysfunction-associated steatotic liver disease

    Arto, C, Rusu, EC, Clavero-Mestres, H, Barrientos-Riosalido, A, Bertran, L, Mahmoudian, R, Aguilar, C, Riesco, D, Chicote, JU, Parada, D, Martinez, S, Sabench, F, Richart, C, Auguet, T. 01/11/2024. European Journal Of Clinical Investigation. 54. PMID: 38940215. doi: 10.1111/eci.14279

    Dupilumab treatment in paediatric atopic dermatitis (2-18 years): Spanish multicentre retrospective real-world study

    Iznardo, H, Roé, E, Vicente, A, Prat, C, Casals, M, Martín-Santiago, A, Esteve, A, Viñas, M, Munera-Campos, M, Corella, F, Mollet, J, Figueras-Nart, I, Vila, A, Soria, X, Azón-Masoliver, A, Marqués-Martín, L, Nadal-Lladó, C, Bel, S, Pujol-Montcusí, J, Bertolín-Colilla, M, Curto-Barredo, L, Melé-Ninot, G, Evole, M, Berbegal, L, Puig, L, Baselga, E. 30/10/2024. Clinical And Experimental Dermatology. 50. PMID: 39093288. doi: 10.1093/ced/llae300

    Differential analysis of lipoprotein and glycoprotein profiles in bacterial infections and COVID-19 using proton nuclear magnetic resonance and machine learning

    Iftimie, S, Amigó, N, Martínez-Micaelo, N, López-Azcona, AF, Martínez-Navidad, C, Castañé, H, Jiménez-Franco, A, Ribalta, J, Parra, S, Castro, A, Camps, J, Joven, J. 15/09/2024. Heliyon. 10. PMID: 39286163. doi: 10.1016/j.heliyon.2024.e37115

    Lipidomic and metabolomic changes in community-acquired and COVID-19 pneumonia

    Saballs, M, Parra, S, Martínez, N, Amigo, N, Cabau, L, Iftimie, S, Pavon, R, Gabaldó, X, Correig, X, Paredes, S, Vallvé, JM, Castro, A. 01/09/2024. Journal Of Lipid Research. 65. PMID: 39154734. doi: 10.1016/j.jlr.2024.100622

    FACTORS AFFECTING PERSISTENCE OF DENOSUMAB TREATMENT IN PATIENTS WITH OSTEOPOROSIS: A RETROSPECTIVE COHORT STUDY

    Costa, E, Paredes, S, Taverner, D, Pàmies, A, Tomas, C, Llop, D, Llop, C. 01/08/2024. Aging Clinical And Experimental Research. 36

    Contributing to the management of viral infections through simple immunosensing of the arachidonic acid serum level

    Torrente-Rodríguez, RM, Montiel, VRV, Iftimie, S, Montero-Calle, A, Pingarrón, JM, Castro, A, Camps, J, Barderas, R, Campuzano, S, Joven, J. 01/07/2024. MICROCHIMICA ACTA. 191. PMID: 38834823. doi: 10.1007/s00604-024-06440-y

    Serum Levels of Arachidonic Acid, Interleukin-6, and C-Reactive Protein as Potential Indicators of Pulmonary Viral Infections: Comparative Analysis of Influenza A, Respiratory Syncytial Virus Infection, and COVID-19

    Iftimie, S, Gabaldó-Barrios, X, Penadés-Nadal, J, Canela-Capdevila, M, Piñana, R, Jiménez-Franco, A, López-Azcona, AF, Castañé, H, Cárcel, M, Camps, J, Castro, A, Joven, J. 01/07/2024. Viruses-Basel. 16. PMID: 39066228. doi: 10.3390/v16071065

    External Validation of the Machine Learning-Based Thermographic Indices for Rheumatoid Arthritis: A Prospective Longitudinal Study

    Morales-Ivorra, I, Taverner, D, Codina, O, Castell, S, Fischer, P, Onken, D, Martínez-Osuna, P, Battioui, C, Marín-López, MA. 01/07/2024. Diagnostics. 14. PMID: 39001284. doi: 10.3390/diagnostics14131394

    Validation of prognostic and predictive value of total tumoral load after primary systemic therapy in breast cancer using OSNA assay

    Bernet-Vegué, L, Cantero-González, C, de Salas, MS, Parada, D, Perin, T, Quintero-Niño, Z, Pérez-Quintela, BV, Sánchez-Guzman, D, Castelvetere, M, Hernaez, DH, Martín-Salvago, MD. 01/05/2024. Clinical & Translational Oncology. 26. PMID: 38070048. doi: 10.1007/s12094-023-03347-7

    Changes in oxidative stress and the inflammatory system in breast cancer patients

    Avila, VDC, Franco, AJ, Capdevila, MC, Pablo, RG, Aguilar, JMJ, Casta , H, Mora, PA, Chac n, BAM, Benitez, G, Acosta, JC, Benavides, R, Troncho, CE, Engel, O, Parada, D, De la Flor, M, Jord , C, Mel , M, Repkova, J, Prat, MA. 01/05/2024. Radiotherapy And Oncology. 194

    Retrospective Analysis of Clostridioides difficile Infection Rates and Outcomes in Hospitalized Patients during the COVID-19 Pandemic: A Unicenter Study in Reus, Spain

    Iftimie, S, López-Azcona, AF, Corchero-Valverde, M, Peralta-Vázquez, A, López-Cordón, LR, García-Cervera, C, Fernández-Domínguez, LM, Camps, J, Joven, J, Castro, A. 01/05/2024. Journal of clinical medicine. 13. PMID: 38792341. doi: 10.3390/jcm13102799

    Exposure to different occupational chemicals and clinical phenotype of a cohort of patients with systemic sclerosis

    Freire, M, Sopeña, B, González-Quintela, A, del Castillo, AG, Moraga, EC, Lledó-Ibañez, GM, Rubio-Rivas, M, Trapiella, L, Argibay, A, Tolosa, C, Alfonso, BM, Vargas-Hitos, JA, Salas, XP, González-Echávarri, C, Chamorro, AJ, Fraile, IP, García, AG, Bellvis, GD, Bello, DB, Salomo, AC, de Heredia, IJP, Marín-Ballve, A, Rodríguez-Píntó, I, Saez-Comet, L, Ortego-Centeno, N, Todolí-Parra, JA, Pla, VF, Simeón-Aznar, CP. 01/05/2024. Autoimmunity Reviews. 23. PMID: 38599508. doi: 10.1016/j.autrev.2024.103542

    Assessing the Utility of Multiplexed Polymerase Chain Reaction in Detecting Microorganisms Causing Infections in Critically ill Patients

    Garrido, P, Gabaldó-Barrios, X, Pujol-Bajador, I, Fernández, L, Ballester, F, Garrido, R, Cueto, P, Camps, J, Vallverdu, I. 01/11/2023. Current Microbiology. 80. PMID: 37733061. doi: 10.1007/s00284-023-03461-3

    Plasma Expression of Carotid Plaque Presence-Related MicroRNAs Is Associated with Inflammation in Patients with Rheumatoid Arthritis

    Llop, D, Paredes, S, Ibarretxe, D, Taverner, D, Plana, N, Rosales, R, Masana, L, Vallvé, JC. 01/10/2023. International Journal Of Molecular Sciences. 24. PMID: 37895027. doi: 10.3390/ijms242015347

    Opportunistic genetic screening increases the diagnostic yield and is medically valuable for care of patients and their relatives with hereditary cancer

    Fernández-Castillejo, S, Roig, B, Melé, M, Serrano, S, Salvat, M, Querol, M, Brunet, J, Pineda, M, Cisneros, A, Parada, D, Badia, J, Borràs, J, Rodríguez-Balada, M, Gumà, J. 17/08/2023. Journal Of Medical Genetics. 61. PMID: 37591735. doi: 10.1136/jmg-2023-109389

    Paraoxonase-1: How a xenobiotic detoxifying enzyme has become an actor in the pathophysiology of infectious diseases and cancer

    Camps, J, Iftimie, S, Arenas, M, Castañé, H, Jiménez-Franco, A, Castro, A, Joven, J. 01/08/2023. Chemico-Biological Interactions. 380. PMID: 37201624. doi: 10.1016/j.cbi.2023.110553

    Blood Liquid Biopsy in an Advanced Medullary Thyroid Carcinoma: A Case Study with Rearranged during Transfection Heterogeneity

    Gumà, J, Peña, KB, Riu, F, Lucia-Gozálvez, C, Vidaller, A, Maldonado, V, Parada, D. 01/08/2023. Pathobiology. 90. PMID: 36731433. doi: 10.1159/000527184

    The concentrations of essential/toxic elements in serum of COVID-19 patients are not directly related to the severity of the disease

    Marquès, M, Iftimie, S, Camps, J, Joven, J, Domingo, JL. 01/07/2023. Journal Of Trace Elements In Medicine And Biology. 78. PMID: 36996642. doi: 10.1016/j.jtemb.2023.127160

    Low HDL-c levels at admission are associated with greater severity and worse clinical outcomes in patients with COVID-19 disease

    Parra, S, Saballs, M, DiNubile, M, Feliu, M, Iftimie, S, Revuelta, L, Pavón, R, Avila, A, Levinson, S, Castro, A. 01/06/2023. Atherosclerosis Plus. 52. PMID: 36910513. doi: 10.1016/j.athplu.2023.01.002

    Study of Liquid-Based Cytology Using Next-Generation Sequencing as a Liquid Biopsy Application in Patients with Advanced Oncological Disease

    Peña, KB, Riu, F, Hernandez, A, Guilarte, C, Elizalde-Horcada, M, Parada, D. 01/06/2023. Biomedicines. 11. PMID: 37371673. doi: 10.3390/biomedicines11061578

    A panel of plasma microRNAs improves the assessment of surrogate markers of cardiovascular disease in rheumatoid arthritis patients

    Llop, D, Ibarretxe, D, Plana, N, Rosales, R, Taverner, D, Masana, L, Vallvé, JC, Paredes, S. 03/04/2023. Rheumatology. 62. PMID: 36048908. doi: 10.1093/rheumatology/keac483

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    Iftimie, S, López-Azcona, AF, Lozano-Olmo, MJ, Naval-Ferrando, A, Domingo-Cortés, V, Castañé, H, Jiménez-Franco, A, Hernández-Aguilera, A, Guilarte, C, Riu, F, Camps, J, Joven, J, Castro, A. 01/04/2023. Viruses-Basel. 15. PMID: 37112865. doi: 10.3390/v15040886

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    Segura, S, Podlipnik, S, Boada, A, Marti, RM, Sabat, M, Yélamos, O, Zarzoso-Muñoz, I, Azón-Masoliver, A, López-Castillo, D, Solà, J, Baliu-Piqué, C, Galvany-Rossell, L, Pasquali, P, Just-Sarobé, M, Duran, X, Carrera, C, Richarz, NA, Pujol, RM, Malvehy, J, Puig, S. 01/12/2023. Melanoma Research. 33. PMID: 37696262. doi: 10.1097/CMR.0000000000000923

    Report on the first two confirmed autochthonous cases of West Nile virus encephalitis in Catalonia, Spain

    García-Cervera, C, Iftimie, SM, Martínez, MJ, González, AV, Parra-Pérez, S, Revuelta-López-Cordón, L, Gil-Toral, J, Vallverdú, RMV, Mateo, AM, López-Azcona, AF, Pujol-Bajador, I, Ballester-Bastardie, F, Castro-Salomó, A. 02/11/2023. INFECTIOUS DISEASES. 55. PMID: 37471287. doi: 10.1080/23744235.2023.2236703

    Cloxacillin plus fosfomycin versus cloxacillin alone for methicillin-susceptible Staphylococcus aureus bacteremia: a randomized trial

    Grillo, S, Pujol, M, Miró, JM, López-Contreras, J, Euba, G, Gasch, O, Boix-Palop, L, Garcia-País, MJ, Pérez-Rodríguez, MT, Gomez-Zorrilla, S, Oriol, I, López-Cortés, LE, Pedro-Botet, ML, San-Juan, R, Aguado, JM, Gioia, F, Iftimie, S, Morata, L, Jover-Sáenz, A, García-Pardo, G, Loeches, B, Izquierdo-Cárdenas, A, Goikoetxea, AJ, Gomila-Grange, A, Dietl, B, Berbel, D, Videla, S, Hereu, P, Padulles, A, Pallarès, N, Tebé, C, Cuervo, G, Carratalà, J, SAFO Study Grp. 01/10/2023. Nature Medicine. 29. PMID: 37783969. doi: 10.1038/s41591-023-02569-0

    Treatment of COVID-19 pneumonia with low-dose radiotherapy plus standard of care versus standard of care alone in frail patients The SEOR-GICOR IPACOVID comparative cohort trial

    Arenas, M, Piqué, B, Torres-Royo, L, Acosta, JC, Rodríguez-Tomàs, E, De Febrer, G, Vasco, C, Araguas, P, Gómez, JA, Malave, B, Arquez, M, Algara, M, Montero, A, Montero, M, Simó, JM, Gabaldó, X, Parada, D, Riu, F, Sabater, S, Camps, J, Joven, J. 01/09/2023. Strahlentherapie Und Onkologie. 199. PMID: 37000224. doi: 10.1007/s00066-023-02067-9

    Predictive Factors of the Use of Rituximab and Belimumab in Spanish Lupus Patients

    Capdevila, O, Mitjavila, F, Espinosa, G, Caminal-Montero, L, Marín-Ballvè, A, León, RG, Castro, A, Canora, J, Pinilla, B, Fonseca, E, Ruiz-Irastorza, G, Autoimmune Dis Study Grp GEAS. 01/08/2023. Medicina-Lithuania. 59. PMID: 37629652. doi: 10.3390/medicina59081362

    Treatment of COVID-19 pneumonia with low-dose radiotherapy in frail patients

    Chacon, BAM, Arteaga, JCA, Piqué, B, Torres-Royo, L, Rodríguez-Tomás, E, Benavides, R, De Febrer, G, Araguas, P, Gomez, JA, Arquez, M, Calderon, VD, Algara, M, Montero, A, Parada, D, Riu, F, Jiménez, A, Vasco, C, Sabater, S, Camps, J, Joven, J, Prat, MA. 01/05/2023. Radiotherapy And Oncology. 182

    Reactive ileal lymphoid hyperplasia related to SARS-CoV-2 infection as a unique clinical feature resembling Crohn's disease

    Qanneta, R, Feliu-Masgoret, M, García-Pardo, G, Marimon-Cortés, F. 01/02/2023. Revista de gastroenterologia de Mexico. 88. PMID: 35783558. doi: 10.1016/j.rgmx.2022.05.006

    Immunohistochemical Algorithm for the Classification of Muscle-Invasive Urinary Bladder Carcinoma with Lymph Node Metastasis: An Institutional Study

    Peña, KB, Riu, F, Gumà, J, Martínez-Madueño, F, Miranda, MJ, Vidal, A, Grifoll, M, Badia, J, Rodriguez-Balada, M, Parada, D. 01/12/2022. Journal of clinical medicine. 11. PMID: 36556046. doi: 10.3390/jcm11247430

    Utility of ctDNA Liquid Biopsies from Cancer Patients: An Institutional Study of 285 ctDNA Samples

    Gumà, J, Peña, K, Riu, F, Guilarte, C, Hernandez, A, Lucía, C, Martínez-Madueño, F, Miranda, MJ, Cabezas, I, Grifoll, M, Peralta, S, Serrano, S, Muñoz, F, Delamo, L, Roig, B, Borràs, J, Badia, J, Rodriguez-Balada, M, Parada, D. 01/12/2022. Cancers. 14. PMID: 36497340. doi: 10.3390/cancers14235859

    The 2022 ENCR Recommendations on recording and reporting of urothelial tumours of the urinary tract

    Galceran, J, Parada, D, Eden, M, Tumino, R, Warren, AY, Martos, C, Neamtiu, L, Visser, O, Daubisse-Marliac, L. 23/11/2022. Frontiers in oncology. 12. PMID: 36505871. doi: 10.3389/fonc.2022.1046239

    Characteristics of hospitalized patients with SARS-CoV-2 infection during successive waves of the COVID-19 pandemic in a reference hospital in Spain

    Iftimie, S, López-Azcona, AF, Lozano-Olmo, MJ, Hernández-Aguilera, A, Sarrà-Moretó, S, Joven, J, Camps, J, Castro, A. 17/10/2022. Scientific Reports. 12. PMID: 36253391. doi: 10.1038/s41598-022-22145-9

    Measurement of Plasma Galectin-3 Concentrations in Patients with Catheter Infections: A Post Hoc Retrospective Cohort Study

    Iftimie, S, Hernández-Aguilera, A, López-Azcona, AF, Castañé, H, Rodríguez-Tomàs, E, Baiges-Gaya, G, Camps, J, Castro, A, Joven, J. 01/10/2022. Diagnostics. 12. PMID: 36292107. doi: 10.3390/diagnostics12102418

    Adjunctive Recombinant Human Plasma Gelsolin for Severe Coronavirus Disease 2019 Pneumonia

    DiNubile, MJ, Parra, S, Salomó, AC, Levinson, SL. 02/08/2022. Open forum infectious diseases. 9. PMID: 35928505. doi: 10.1093/ofid/ofac357

    Decreased mortality among patients with catheter- related bloodstream infections at Catalan hospitals (2010-2019)

    Badia-Cebada, L, Peñafiel, J, López-Contreras, J, Pomar, V, Martínez, JA, Santana, G, Cuquet, J, Montero, MM, Hidalgo-López, C, Andrés, M, Gimenez, M, Quesada, MD, Vaqué, M, Iftimie, S, Gudiol, C, Pérez, R, Coloma, A, Marron, A, Barrufet, P, Marimon, M, Lérida, A, Clarós, M, Ramírez-Hidalgo, MF, Pardo, GG, Martinez, MJ, Chamarro, EL, Jiménez-Martínez, E, Hornero, A, Limón, E, López, M, Calbo, E, Pujol, M, Gasch, O. 01/08/2022. Journal Of Hospital Infection. 126. PMID: 35594988. doi: 10.1016/j.jhin.2022.05.009

    Usefulness of the Measurement of Serum Paraoxonase-1 Arylesterase Activity in the Diagnoses of COVID-19

    Gabaldó, X, Juanpere, M, Castañé, H, Rodríguez-Tomàs, E, López-Azcona, AF, Baiges-Gaya, G, Castro, L, Valverde-Díaz, E, Muñoz-Blázquez, A, Giménez-Cuenca, L, Felipo-Balada, L, Ballester, F, Pujol, I, Simó, JM, Castro, A, Iftimie, S, Camps, J, Joven, J. 01/07/2022. Biomolecules. 12. PMID: 35883435. doi: 10.3390/biom12070879

    Usefulness of the Urine Methylation Test (Bladder EpiCheck®) in Follow-Up Patients with Non-Muscle Invasive Bladder Cancer and Cytological Diagnosis of Atypical Urothelial Cells-An Institutional Study

    Peña, KB, Riu, F, Hernandez, A, Guilarte, C, Badia, J, Parada, D. 01/07/2022. Journal of clinical medicine. 11. PMID: 35807141. doi: 10.3390/jcm11133855

    Inter- and intra-observer variability in the selection of therapy for infantile hemangiomas among pediatric dermatologists in Spain

    Colmenero, M, del Boz, J, Wittel, JB, Roé, E, Feito-Rodríguez, M, Vicente-Villa, MA, Martín-Santiago, A, Pérez, SIP, Azon, A, Valdivielso-Ramos, M, Torrelo, A, Moya, AIS, Campos-Domínguez, M, Garnacho-Saucedo, G, Defez, JMA, Casaño, AV, Tercedor-Sánchez, J, Alcalá, R, González-Enseyat, MA, Giacaman, A, Hernández-Martin, A, García, MTM, Bauzá, A, Domínguez-Cruz, J, García-Doval, I, Grau-Pérez, M. 01/07/2022. Pediatric Dermatology. 39. PMID: 35504688. doi: 10.1111/pde.15015

    Immunocytochemical Assessment of ACE2 and TMPRSS2 in Nasopharyngeal Swabs from SARS-CoV-2 Patients

    Peña, KB, Gumà, J, Guilarte, C, Delamo, L, Grifol, M, Pique, B, Hernandez, A, Casteñé, H, Riu, F, Parada, D. 24/06/2022. Frontiers In Bioscience-Landmark. 27. PMID: 35866407. doi: 10.31083/j.fbl2707217

    Effect of Low-Dose Radiotherapy on the Circulating Levels of Paraoxonase-1-Related Variables and Markers of Inflammation in Patients with COVID-19 Pneumonia

    Rodríguez-Tomàs, E, Acosta, JC, Torres-Royo, L, De Febrer, G, Baiges-Gaya, G, Castañé, H, Jiménez, A, Vasco, C, Araguas, P, Gómez, J, Malave, B, Arquez, M, Calderón, D, Piqué, B, Algara, M, Montero, A, Simó, JM, Gabaldó-Barrios, X, Sabater, S, Camps, J, Joven, J, Arenas, M. 01/06/2022. Antioxidants. 11. PMID: 35740079. doi: 10.3390/antiox11061184

    EFFECTS OF INHIBITOR K-CARRAGEENAN ON HAECS INFLAMMATORY RESPONSE TO LDLS ISOLATED FROM SLE PATIENTS

    Parra, S, Avila, A, Rivalta, J, Guardiola, M, Rodriguez, R, Castro, A. 01/06/2022. Annals Of The Rheumatic Diseases. 81. doi: 10.1136/annrheumdis-2022-eular.4950

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    Rodriguez-Muguruza, S, Castro, S, Poveda, MJ, Paredes, S, Taverner, D, Fontova, R. 01/06/2022. Annals Of The Rheumatic Diseases. 81. doi: 10.1136/annrheumdis-2022-eular.1138

    Machine learning and semi-targeted lipidomics identify distinct serum lipid signatures in hospitalized COVID-19-positive and COVID-19-negative patients

    Castañé, H, Iftimie, S, Baiges-Gaya, G, Rodríguez-Tomás, E, Jiménez-Franco, A, López-Azcona, AF, Garrido, P, Castro, A, Camps, J, Joven, J. 01/06/2022. Metabolism-Clinical And Experimental. 131. PMID: 35381232. doi: 10.1016/j.metabol.2022.155197

    Clinical Outcome and Radiologic Changes in SARS-CoV-2 Pneumonia treated with Low-Dose Radiotherapy.

    Arteaga, JCA, Royo, LT, Rodríguez-Tomás, E, De Febrer, G, Vasco, C, Gomez, JA, Araguas, P, Malave, B, Arquez, M, Algara, M, Montero, A, Montero, M, Simo, JM, Gavaldà, X, Pique, B, Parada, D, Sabater, S, Camps, J, Joven, J, Arenas, M. 01/05/2022. Radiotherapy And Oncology. 170

    Can COVID-19 vaccines relieve severe tension-type headache and migraine?

    González-Menacho, J, Villas-Roca, M, Castañé, H, Joven, J, Camps, J, Iftimie, S. 01/04/2022. Medical Hypotheses. 161. PMID: 35221450. doi: 10.1016/j.mehy.2022.110812

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    Daubisse-Marliac, L, Grosclaude, P, Carulla, M, Parada, D, Vilardell, L, Ameijide, A, Marcos-Gragera, R, Galceran, J. 01/03/2022. International Journal of Environmental Research and Public Health. 19. PMID: 35270406. doi: 10.3390/ijerph19052714

    Triglyceride-Rich Lipoproteins and Glycoprotein A and B Assessed by 1H-NMR in Metabolic-Associated Fatty Liver Disease

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    Characterization of the LPS and 3OHFA Contents in the Lipoprotein Fractions and Lipoprotein Particles of Healthy Men

    Rehues, P, Rodríguez, M, Alvarez, J, Jiménez, M, Melià, A, Sempere, M, Balsells, C, Castillejo, G, Guardiola, M, Castro, A, Ribalta, J. 01/01/2022. Biomolecules. 12. PMID: 35053195. doi: 10.3390/biom12010047

    Association Among Polyphenol Intake, Uric Acid, and Hyperuricemia: A Cross-Sectional Analysis in a Population at High Cardiovascular Risk

    Rubín-García, M, Vitelli-Storelli, F, Alvarez-Alvarez, L, Martínez-González, MA, Salas-Salvadó, J, Corella, D, Hernáez, A, Martínez, JA, Alonso-Gómez, AM, Wärnberg, J, Vioque, J, Romaguera, D, López-Miranda, J, Estruch, R, Tinahones, FJ, Serra-Majem, LI, Cano-Ibañez, N, Tur, JA, Marcos-Delgado, A, Tresserra-Rimbau, A, Pintó, X, Delgado-Rodríguez, M, Matía-Martín, P, Vidal, J, Vázquez, C, Daimiel, L, Ros, E, Vázquez-Ruiz, Z, Babio, N, Barragán, R, Castañer-Niño, O, Razquin, C, Tojal-Sierra, L, Gómez-Gracia, E, González-Palacios, S, Morey, M, García-Rios, A, Castro-Barquero, S, Bernal-López, MR, Santos-Lozano, JM, Ruiz-Canela, M, Castro-Salomó, A, Pascual-Castelló, EC, Moldon, V, Bullón-Vela, V, Sorto-Sanchez, C, Cenoz-Osinaga, JC, Gutiérrez, L, Mengual, M, Lamuela-Raventós, RM, Martín-Sánchez, V. 18/10/2022. Journal of the American Heart Association. 11. PMID: 36205262. doi: 10.1161/JAHA.122.026053

    Standardized incidence ratios and risk factors for cancer in patients with systemic sclerosis: Data from the Spanish Scleroderma Registry (RESCLE)

    Carbonell, C, Marcos, M, Guillén-Del-Castillo, A, Rubio-Rivas, M, Argibay, A, Marín-Ballvé, A, Rodríguez-Pintó, I, Baldà-Masmiquel, M, Callejas-Moraga, E, Colunga, D, Sáez-Comet, L, González-Echávarri, C, Ortego-Centeno, N, Marí-Alfonso, B, Vargas-Hitos, JA, Todolí-Parra, JA, Trapiella, L, Herranz-Marín, MT, Freire, M, Castro-Salomó, A, Perales-Fraile, I, Madroñero-Vuelta, AB, Sánchez-García, ME, Ruiz-Muñoz, M, González-García, A, Sánchez-Redondo, J, De-la-Red-Bellvis, G, Fernández-Luque, A, Muela-Molinero, A, Lledó, GM, Tolosa-Vilella, C, Fonollosa-Pla, V, Chamorro, AJ, Simeón-Aznar, CP. 01/10/2022. Autoimmunity Reviews. 21. PMID: 35931315. doi: 10.1016/j.autrev.2022.103167

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