Presentació dels Hospitals
Col·labora

Oncologia Radioteràpica

ONCOLOGIA
BIOMARCADORS CÀNCER TECNOLOGIA
OBJECTIUS

Identificació de biomarcadors pronòstics i predictius de resposta als tractaments oncològics en el càncer de mama, pulmó, cap i coll, colorectal i pròstata basats en estrès oxidatiu, metabolisme i immunitat, per tal d’avançar en la personalització en oncologia. Recerca en radiogenòmica. Estudis dels efectes antiinflamatoris de la radioteràpia a dosis baixes en patologia benigna. Estudis amb relació als avenços tecnològics de les diferents tècniques de radioteràpia (IMRT, VMAT, 4D, SBRT, entre d’altres).

RESPONSABLES

  • Dra. Meritxell Arenas Prat

  • Presentació
  • Línies de recerca
  • Projectes
  • Membres del grup
  • Guies de pràctica clínica
  • Difusió
  • Publicacions
  • Contacte

El Grup de Recerca en Oncologia Radioteràpica de l’Institut de Recerca Biomèdica Catalunya Sud (IRB CatSud) es va iniciar l’any 2010 i està constituït per un equip multidisciplinari format per oncòlegs, físics, nutricionistes, enginyers, infermeres… amb una activitat assistencial que es dedica principalment als pacients amb càncer. Pertanyen al Servei de Ràdio-oncologia de l’Hospital Universitari Sant Joan de Reus (HUSJR) que és el Centre Sanitari de Referència per al tractament radiològic del càncer de pacients diagnosticats a la província de Tarragona, Espanya, amb una àrea d’influència d’una població de 813.000 habitants. L’any 2020, 2100 pacients van ser atesos al Servei. El Servei de Radioteràpia atén pacients de diferents hospitals de la província de Tarragona. La línia principal de recerca bàsica és “Marcadors predictius de resposta en càncer de mama”. El RGRO també desenvolupa projectes juntament amb altres grups de recerca de l’IRB CatSud (Unitat de Recerca Biomèdica (URB)) i la Universitat Rovira i Virgili (URV). El grup ha publicat 150 articles indexats en revistes d’abast internacional, així com en més de 450 comunicacions a congressos nacionals i internacionals.

L’equip de recerca té una àmplia experiència en l’estudi dels canvis metabòlics mediats per la disfunció mitocondrial en càncer de mama, pulmó, recte i cap i coll després de la radioteràpia. L’equip de recerca també col·labora amb el grup de Robòtica Intel·ligent i Visió per Computador de la Universitat Rovira i Virgili en l’anàlisi d’imatges mèdiques i estudis d’aprenentatge automàtic.

Una línia de recerca addicional del grup és sobre els efectes antiinflamatoris de la radioteràpia a dosis baixes en malalties benignes.

  • Identificació de biomarcadors i biosensors pronòstics i predictius de resposta en diferents tipus de càncer.
  • Radiogenòmica en càncer de pulmó i càncer de mama.
  • Efectes antiinflamatoris de la radioteràpia en patologia benigna.
  • Estudis sobre els avenços tecnològics de la radioteràpia.

  • Name of the project: Identification of biomarkers based on energy, metabolism, oxidative stress and immune system in patients with breast cancer.
    Entity where project took place: Institut d’Investigacions Sanitàries Pere Virgili, Reus
    Funding entity or bodies: Varian Ibérica, S.L. Tipo de entidad: Entidad Empresarial
    Start-End date: 07/09/2020 – 06/09/2021

    Duración: 1 año
    Total amount: 54.000 €

  • Name of the project: Radioterapia antiinflamatoria a dosis bajas para el tratamiento de la neumonía por covid- 19: estudio prospectivo multicéntrico (ipacovid).
    Entity where project took place: Institut d’Investigacions Sanitàries Pere Virgili, Reus
    Funding entity or bodies: Grupo de Investigación Clínica en Oncología Radioterápica
    Start-End date: 2020 – 2021

    Duración: 1 año

  • Name of the project: Biomarcadores en sangre de pacientes con cáncer de mama
    Geographical area: Regional
    Degree of contribution: Researcher
    Name principal investigator (PI, Co-PI….): Meritxell Arenas; Jorge Camps Andreu
    Start date: 2019

    Duración: 1 año
    Total amount: 11.000 €

  • Name of the project: Estudi del metabolismo energético, la oxidación y la inflamación como posibles biomarcadores de la respuesta al tratamiento con radioterapia en el cáncer de pulmón
    Geographical area: Regional
    Degree of contribution: Researcher
    Name principal investigator (PI, Co-PI….): Meritxell Arenas; Jorge Camps Andreu
    Start date: 2018

    Duración: 1 año
    Total amount: 11.000 €

  • Name of the project: Evaluar la probabilidad de la no adherencia al tratamiento de radioterapia externa y sus factores asociados en los pacientes tratados por cáncer en Cataluña.
    Entity where project took place: Pla Director d’Oncologia. ICO Hospitalet
    Start-End date: 03/10/2016 – 03/12/2018

    Duración: 3 años
    Total amount: 72.000 €

  • Name of the project: Proyecto IA-Biobreast: Anlálisis de caracteristicas texturales a nivel de pixel y fusión de información multimodal. Degree of contribution: Researcher
    Entity where project took place: Universitat Rovira i Virgili
    Funding entity or bodies: Ministerio de Economía y Economia
    Start-End date: 01/01/2012 – 31/12/2015

    Duration: 2 years
    Total amount: 23.595 €

  • Name of the project: Escaneo e Impresión 3D para el tratamiento radioterápico del cáncer de piel o tumores con afectación cutánea
    Degree of contribution: Researcher
    Name principal investigator (PI, Co-PI….): Meritxell Arenas Prat; Doménec Puig
    Start date: 01/01/2016

    Duration: 1 year – 11 months
    Total amount: 3.000 €

  • Name of the project: Biomarcadores pronósticos y predictivos de respuesta a la Radioterapia en el càncer de mama.
    Degree of contribution: Researcher
    Name principal investigator (PI, Co-PI….): Meritxell Arenas Prat; Jordi Camps
    Start date: 01/09/2015

    Duration: 2 years – 3 months
    Total amount: 3.000 €

  • Name of the project: Paraoxonasa-1 y MCP-1 como a possibles marcadores de la respuesta al tratamiento con radioterapia en pacientes con cáncer de cabeza y cuello localmente avanzado, pulmón inoperable y cáncer de mama.
    Degree of contribution: Researcher
    Name principal investigator (PI, Co-PI….): Meritxell Arenas Prat; Jorge Camps Andreu
    Start date: 2015

    Duration: 1 year – 11 months
    Total amount: 4.000 €

  • Documento de consenso conjunto SEC-SEOM-SEOR-SEHH-SEMG-AEEMT-AEEC en el
    manejo del riesgo cardiovascular en la práctica clínica. Miembro del grupo de trabajo
    Entidad de realización: Sociedad Española de Cardiología
    Fecha de inicio: 2020

  • Elaboración de la guía de Tumores esofágicos ICO-Praxis. Miembro del grupo de trabajo. Dr. Trilla.
    Entidad de realización: Institut Català d’Oncologia (ICO)
    Fecha de inicio: 2020

  • Elaboración de la guía para el manejo coordinado de trabajadores con cáncer y riesgo
    cardiovascular. Miembro del grupo de trabajo
    Entidad de realización: Sociedad Española de Cardiología
    Fecha de inicio: 2019

  • Elaboración de la guía de Linfomas ICO-Praxis. Miembro del grupo de trabajo. Dra. López.
    Entidad de realización: Institut Català d’Oncologia (ICO)
    Fecha de inicio: 2019

  • Participación en el proyecto de indicadores de calidad en Oncología Radioterápica.
    Miembro del grupo de trabajo
    Entidad de realización: Sociedad Española de Oncología radioterápica.
    Fecha de inicio: 2019

    Año

    Post-Radiotherapy Changes in Circulating Dodecanoic Acid Identify Metabolic Phenotypes Associated with Recurrence in Breast Cancer.

    Jiménez-Franco A, Cambra-Cortés V, García-Pablo R, Canela-Capdevila M, Benavides-Villarreal R, Gabaldó-Barrios X, Fort-Gallifa I, Camps J, Joven J, Arenas M. 26/02/2026. Biomolecules. 16. PMID: 41897292. doi: 10.3390/biom16030355

    ERG expression is not predictive of outcome in patients with intermediate- and high-risk localized prostate cancer treated with combined androgen blockade and radiotherapy

    Henriquez, I, Malave, B, Benitez-Gabella, G, Parada, D, Canela, M, García-Pablo, R, Benavides, R, Rius, F, Arenas, M. 01/02/2026. Clinical & Translational Oncology. 28. PMID: 40788562. doi: 10.1007/s12094-025-04016-7

    Guide for quality control and safety of external radiotherapy treatment planning systems and treatment plans.

    García-Romero A, Baeza-Trujillo M, Teijeiro-García A, Clemente-Gutiérrez F, Morera-Cano D, Hernández-Masgrau V. 01/01/2026. Physica Medica-European Journal Of Medical Physics. 141. PMID: 41478049. doi: 10.1016/j.ejmp.2025.105699

    Influence of the Molecular Subtype-Dependent Immune Microenvironment of Metastatic Axillary Lymph Nodes on Breast Cancer Patient Outcomes.

    López C, Reverté L, Bosch Príncep R, Sauras E, Gallardo-Borràs N, Fischer-Carles A, Korzynska A, García-Rojo M, Bueno G, Roszkowiak L, Roso-LLorach A, Gras Navarro A, Llobera M, Mata D, Adalid Llansa L, Martínez-González S, Garcia-Fontgivell JF, Arenas M, Gómez J, Izuel JA, Baucells J, Lejeune M. 31/12/2025. Pathobiology. PMID: 41474659. doi: 10.1159/000550086

    Quantification of the aperture modulation in radiotherapy treatment plans

    Hernandez, V, Lara-Aristimuño, I, Abella, R, Saez, J. 19/11/2025. Medical Physics. 52. PMID: 41261086. doi: 10.1002/mp.70144

    Artificial intelligence-driven integration of multi-omics and radiomics: A new hope for precision cancer diagnosis and prognosis

    Camps, J, Jiménez-Franco, A, García-Pablo, R, Joven, J, Arenas, M. 01/08/2025. Biochimica Et Biophysica Acta-Molecular Basis Of Disease. 1871. PMID: 40216368. doi: 10.1016/j.bbadis.2025.167841

    Burnout levels among radiation oncology residents in Spain: a cross-sectional survey

    Sellés, EG, de León, MM, Montero, A, Arenas, M. 01/08/2025. Clinical & Translational Oncology. 27. PMID: 39937361. doi: 10.1007/s12094-025-03862-9

    Artificial intelligence and radiomics-based models to predict clinical response to low-dose radiotherapy in arthrodegenerative pathology

    Brull, PM, Capdevila, MC, Pablo, RG, Caballero, AM, Ramírez, JO, Sánchez, YL, Franco, AJ, Aguilar, JMJ, Villarreal, RB, Andreu, JC, Prat, MA, Masgrau, VH. 01/05/2025. Radiotherapy And Oncology. 206

    Artificial Intelligence in the prediction of clinical response in patients with COVID-19 pneumonia treated with low-dose pulmonary radiotherapy

    Ramírez, JO, Smith, BP, Capdevila, MC, Pablo, RG, Caballero, AM, Brull, PM, Franco, AJ, Aguilar, JMJ, Villarreal, RB, Royo, LT, Artiga, JCA, Mora, PA, Avila, VDC, Andreu, JC, Prat, MA, Masgrau, VH. 01/05/2025. Radiotherapy And Oncology. 206

    SIRARIS: Survey of internal mammary radiotherapy among radiation oncologists from Italy & Spain

    Montero, A, Arenas, M, Aistei, C. 01/04/2025. Clinical & Translational Oncology. 27. PMID: 39218812. doi: 10.1007/s12094-024-03693-0

    The 2024 Assisi think tank on breast cancer: Focus on the use of a tumour bed boost after breast conserving therapy

    Arenas, M, Bölükbasi, Y, Boersma, LJ, Offersen, B, Kouloulias, V, Palumbo, I, Trigo, L, Lozza, L, Marazzi, F, Trovo, M, Rivera, S, Kaidar-Person, O, Coles, C, Meattini, I, Valentini, V, Aristei, C, Poortmans, P. 01/04/2025. Breast. 80. PMID: 39854807. doi: 10.1016/j.breast.2025.103881

    Is the Imaging Radiation Oncology Core Head and Neck Credentialing Phantom an Effective Surrogate for Different Anatomic Sites?

    Brooks, FMD, Glenn, MC, Hernandez, V, Saez, J, Pollard-Larkin, JM, Peterson, CB, Howell, RM, Nelson, CL, Clark, CH, Kry, SF. 01/03/2025. International Journal Of Radiation Oncology Biology Physics. 121. PMID: 39362313. doi: 10.1016/j.ijrobp.2024.09.053

    Dataset on the quality of life and neurocognitive effects of prophylactic cranial irradiation, with and without hippocampal avoidance, in small-cell lung cancer patients

    Heredia, L, Murcia-Mejía, M, Torrente, M. 01/02/2025. Data in brief. 58. PMID: 39758519. doi: 10.1016/j.dib.2024.111197

    Intrafraction motion in intra-cranial multi-target stereotactic radiosurgery plans: A multi-institutional investigation on robustness

    May, L, Barnes, M, Hardcastle, N, Hernandez, V, Saez, J, Rosenfeld, A, Poder, J. 01/02/2025. Physica Medica-European Journal Of Medical Physics. 130. PMID: 39854920. doi: 10.1016/j.ejmp.2025.104900

    Survivin/BIRC5 as a novel molecular effector at the crossroads of glucose metabolism and radioresistance in head and neck squamous cell carcinoma

    Benaiges, E, Ceperuelo-Mallafré, V, Guaita, S, Maymó-Masip, E, Madeira, A, Gómez, D, Hernández, V, Vilaseca, I, Merma, C, León, X, Terra, X, Vendrell, J, Avilés-Jurado, FX, Fernández-Veledo, S. 02/02/2024. Head And Neck-Journal For The Sciences And Specialties Of The Head And Neck. 46. PMID: 38305029. doi: 10.1002/hed.27651

    Metabolomics and triple-negative breast cancer: A systematic review

    Arenas, M, Fargas-Saladié, M, Moreno-Solé, M, Moyano-Femenia, L, Jiménez-Franco, A, Canela-Capdevila, M, Castañé, H, Martínez-Navidad, C, Camps, J, Joven, J. 15/01/2024. Heliyon. 10. PMID: 38187259. doi: 10.1016/j.heliyon.2023.e23628

    Recommendation on the technical and dosimetric data to be included in stereotactic body radiation therapy clinical trial publications based on a systematic review.

    Hardcastle N, Josipovic M, Clementel E, Hernandez V, Smyth G, Gober M, Wilke L, Eaton D, Josset S, Lazarakis S, Saez J, Vieillevigne L, Jornet N, Mancosu P. 01/01/2024. Radiotherapy And Oncology. 190. PMID: 38043902. doi: 10.1016/j.radonc.2023.110042

    Multi-institutional generalizability of a plan complexity machine learning model for predicting pre-treatment quality assurance results in radiotherapy.

    Claessens M, De Kerf G, Vanreusel V, Mollaert I, Hernandez V, Saez J, Jornet N, Verellen D. 01/01/2024. PHYSICS & IMAGING IN RADIATION ONCOLOGY. 29. PMID: 38204910. doi: 10.1016/j.phro.2023.100525

    Metabolic adaptations in severe obesity: Insights from circulating oxylipins before and after weight loss

    Jiménez-Franco, A, Castañé, H, Martínez-Navidad, C, Placed-Gallego, C, Hernández-Aguilera, A, Fernández-Arroyo, S, Samarra, I, Canela-Capdevila, M, Arenas, M, Zorzano, A, Hernández-Alvarez, MI, Del Castillo, D, Paris, M, Menendez, JA, Camps, J, Joven, J. 01/01/2024. Clinical Nutrition. 43. PMID: 38101315. doi: 10.1016/j.clnu.2023.12.002

    The Assisi think tank focus review on postoperative radiation for lobular breast cancer

    Kaidar-Person, O, Ratosa,, Franco, P, Masiello, V, Marazzi, F, Pedretti, S, Ciabattoni, A, Leonardi, MC, Tramm, T, Coles, C, Meattini,, Arenas, M, Offersen, BV, Boersma, LJ, Valentini, V, Dodwell, D, Poortmans, P, Aristei, C. 01/12/2024. Radiotherapy And Oncology. 201. PMID: 39395669. doi: 10.1016/j.radonc.2024.110573

    Which failures do patient-specific quality assurance systems need to catch?

    O’Daniel, J, Masgrau, VH, Clark, C, Esposito, M, Lehmann, J, Mcniven, A, Olaciregui-Ruiz, I, Kry, S. 28/10/2024. Medical Physics. 52. PMID: 39466302. doi: 10.1002/mp.17468

    Preliminary Metabolomics Study Suggests Favorable Metabolic Changes in the Plasma of Breast Cancer Patients after Surgery and Adjuvant Treatment

    Jiménez-Franco, A, Jimenez-Aguilar, JM, Canela-Capdevila, M, García-Pablo, R, Castañé, H, Martínez-Navidad, C, Araguas, P, Malavé, B, Benavides-Villarreal, R, Acosta, JC, Onoiu, AI, Somaiah, N, Camps, J, Joven, J, Arenas, M. 01/10/2024. Biomedicines. 12. PMID: 39457508. doi: 10.3390/biomedicines12102196

    Multi-institutional investigation into the robustness of intra-cranial multi-target stereotactic radiosurgery plans to patient setup errors

    May, L, Barnes, M, Hardcastle, N, Hernandez, V, Saez, J, Rosenfeld, A, Poder, J. 01/08/2024. Physica Medica-European Journal Of Medical Physics. 124. PMID: 38970949. doi: 10.1016/j.ejmp.2024.103423

    Combining Metabolomics and Machine Learning to Identify Diagnostic and Prognostic Biomarkers in Patients with Non-Small Cell Lung Cancer Pre- and Post-Radiation Therapy

    Murcia-Mejía, M, Canela-Capdevila, M, García-Pablo, R, Jiménez-Franco, A, Jiménez-Aguilar, JM, Badía, J, Benavides-Villarreal, R, Acosta, JC, Arguís, M, Onoiu, AI, Castañe, H, Camps, J, Arenas, M, Joven, J. 01/08/2024. Biomolecules. 14. PMID: 39199286. doi: 10.3390/biom14080898

    PSMA PET/CT SUVmax as a prognostic biomarker in patients with metachronous metastatic hormone-sensitive prostate cancer (mHSPC)

    Henríquez, I, Malave, B, Campos, FL, Hidalgo, EC, Muelas, R, Ferrer, C, Muñoz-Rodriguez, J, Villamón, AM, Pascual, MC, Badia, J, Fuertes, J, Hinojosa-Salas, P. 29/07/2024. Clinical & Translational Oncology. 27. PMID: 39073734. doi: 10.1007/s12094-024-03625-y

    Immunotherapy and radiotherapy for older patients with invasive bladder cancer unfit for surgery or chemotherapy: practical proposal by the international geriatric radiotherapy group

    Nguyen, NP, Karlsson, UL, Page, BR, Chirila, ME, Vinh-Hung, V, Gorobets, O, Arenas, M, Mohammadianpanah, M, Javadinia, SA, Giap, H, Kim, L, Dutheil, F, Murthy, V, Mallum, AA, Tlili, G, Dahbi, Z, Loganadane, G, Blanco, SC, Bose, S, Natoli, E, Li, E, Morganti, AG. 04/07/2024. Frontiers in oncology. 14. PMID: 39026981. doi: 10.3389/fonc.2024.1371752

    Serum Levels of Arachidonic Acid, Interleukin-6, and C-Reactive Protein as Potential Indicators of Pulmonary Viral Infections: Comparative Analysis of Influenza A, Respiratory Syncytial Virus Infection, and COVID-19

    Iftimie, S, Gabaldó-Barrios, X, Penadés-Nadal, J, Canela-Capdevila, M, Piñana, R, Jiménez-Franco, A, López-Azcona, AF, Castañé, H, Cárcel, M, Camps, J, Castro, A, Joven, J. 01/07/2024. Viruses-Basel. 16. PMID: 39066228. doi: 10.3390/v16071065

    Incorporating plan complexity into the statistical process control of volumetric modulated arc therapy pre-treatment verifications

    Russo, S, Saez, J, Esposito, M, Bruschi, A, Ghirelli, A, Pini, S, Scoccianti, S, Hernandez, V. 01/06/2024. Medical Physics. 51. PMID: 38630979. doi: 10.1002/mp.17081

    Immunotherapy and stereotactic body radiotherapy for older patients with non-metastatic renal cancer unfit for surgery or decline nephrectomy: practical proposal by the International Geriatric Radiotherapy Group

    Nguyen, NP, Chirila, ME, Page, BR, Vinh-Hung, V, Gorobets, O, Mohammadianpanah, M, Giap, H, Arenas, M, Bonet, M, Lara, PC, Kim, L, Dutheil, F, Lehrman, D, Montes, LZ, Tlili, G, Dahbi, Z, Loganadane, G, Blanco, SC, Bose, S, Natoli, E, Li, ER, Mallum, A, Morganti, AG. 24/05/2024. Frontiers in oncology. 14. PMID: 38854736. doi: 10.3389/fonc.2024.1391464

    Changes in oxidative stress and the inflammatory system in breast cancer patients

    Avila, VDC, Franco, AJ, Capdevila, MC, Pablo, RG, Aguilar, JMJ, Casta , H, Mora, PA, Chac n, BAM, Benitez, G, Acosta, JC, Benavides, R, Troncho, CE, Engel, O, Parada, D, De la Flor, M, Jord , C, Mel , M, Repkova, J, Prat, MA. 01/05/2024. Radiotherapy And Oncology. 194

    Metabolic profiling of plasma and tissue in breast cancer patients: uncovering therapeutic response

    Jim nez-Franco, A, Calder n, D, Jim nez-Aguilar, J, Canela-Capdevila, M, Garc a-Pablo, R, Casta , H, Araguas, P, Malave, B, Acosta, JC, Benavides, R, Arquez, M, Casta o, F, Riu, F, De la Flor, M, Jord , C, Mel , M, Repkova, J, Amillano, K, Camps, J, Joven, J, Arenas, M. 01/05/2024. Radiotherapy And Oncology. 194

    A simple method to optimise the radiation isocentre and Winston-Lutz results in linear accelerators

    Vaqu , JP, Lara-Aristimu o, I, Hernandez, V. 01/05/2024. Radiotherapy And Oncology. 194

    Fostering a radiant future: visibility and appeal of Radiation Oncology among your medical graduates

    Sell s, EG, Montero, A, Arenas, M. 01/05/2024. Radiotherapy And Oncology. 194

    Use of Social Media in Radiation Oncology: Multicenter Data from the GOCO Group

    Bonet, M, Recalde, E, Soto-Cambres, AM, Martinez, A, Murcia, M, Nu ez, M, Mases, J, Yufera, JC, Alvarez, A, Feltes, N, Hernandez, L, Ramos, L, Garcia, V. 01/05/2024. Radiotherapy And Oncology. 194

    A prospective, randomized, blinded study on the efficacy of using corticosteroids in hydrodilatation as a treatment for adhesive capsulitis of the shoulder

    Gebellí-Jové, JT, Buñuel-Viñau, A, Canela-Capdevila, M, Camps, J, Sabench, F, Iftimie-Iftimie, P. 20/03/2024. Shoulder & Elbow. 17. PMID: 39552668. doi: 10.1177/17585732241239030

    A radiotherapy community data-driven approach to determine which complexity metrics best predict the impact of atypical TPS beam modeling on clinical dose calculation accuracy

    Brooks, FMD, Glenn, MC, Hernandez, V, Saez, J, Mehrens, H, Pollard-Larkin, JM, Howell, RM, Peterson, CB, Nelson, CL, Clark, CH, Kry, SF. 01/03/2024. Journal of Applied Clinical Medical Physics. 25. PMID: 38427776. doi: 10.1002/acm2.14318

    Influence of chemotherapy regimens prior to nivolumab on the survival of recurrent/metastatic SCCHN.

    Blanco, CM, Palomares, LD, Gonzálvez, CL, Muñoz, SP, Laguna, VM, Llansa, LA, Gómez, DG, Mejía, MM, Pinel, MA, Linares, CM, Padró, JG. 01/03/2024. Radiotherapy And Oncology. 192

    Improving the modelling of a multi-leaf collimator with tilted leaf sides used in radiotherapy.

    Hussein M, Angerud A, Saez J, Bogaert E, Lemire M, Barry M, Silvestre Patallo I, Shipley D, Clark CH, Hernandez V. 01/02/2024. PHYSICS & IMAGING IN RADIATION ONCOLOGY. 29. PMID: 38390588. doi: 10.1016/j.phro.2024.100543

    Multi-institutional investigation into the robustness of intra-cranial multi-target stereotactic radiosurgery plans to delivery errors.

    May L, Hardcastle N, Hernandez V, Saez J, Rosenfeld A, Poder J. 23/12/2023. Medical Physics. 51. PMID: 38141043. doi: 10.1002/mp.16907

    Making Radiation Oncology specialty more attractive to young medical graduates: pulling back the invisibility curtain

    Sellés, EG, Montero, A, Arenas, M. 01/11/2023. Clinical & Translational Oncology. 25. PMID: 37378794. doi: 10.1007/s12094-023-03257-8

    Paraoxonase-1: How a xenobiotic detoxifying enzyme has become an actor in the pathophysiology of infectious diseases and cancer

    Camps, J, Iftimie, S, Arenas, M, Castañé, H, Jiménez-Franco, A, Castro, A, Joven, J. 01/08/2023. Chemico-Biological Interactions. 380. PMID: 37201624. doi: 10.1016/j.cbi.2023.110553

    The 2022 Assisi Think Tank Meeting: White paper on optimising radiation therapy for breast cancer

    Aristei, C, Kaidar-Person, O, Boersma, L, Leonardi, MC, Offersen, B, Franco, P, Arenas, M, Bourgier, C, Pfeffer, R, Kouloulias, V, Bolukbasi, Y, Meattini, I, Coles, C, Luis, AM, Masiello, V, Palumbo, I, Morganti, AG, Perrucci, E, Tombolini, V, Krengli, M, Marazzio, F, Trigo, L, Borghesi, S, Ciabattoni, A, Ratosa, I, Valentini, V, Poortmans, P. 01/07/2023. Critical Reviews In Oncology Hematology. 187. PMID: 37244324. doi: 10.1016/j.critrevonc.2023.104035

    Evaluation of plan complexity and dosimetric plan quality of total marrow and lymphoid irradiation using volumetric modulated arc therapy

    Lambri, N, Dei, D, Hernandez, V, Castiglioni, I, Clerici, E, De Philippis, C, Loiacono, D, Navarria, P, Reggiori, G, Rusconi, R, Tomatis, S, Bramanti, S, Scorsetti, M, Mancosu, P. 01/06/2023. Journal of Applied Clinical Medical Physics. 24. PMID: 37085997. doi: 10.1002/acm2.13931

    Multicentric evaluation of a machine learning model to streamline the radiotherapy patient specific quality assurance process

    Lambri, N, Hernandez, V, Sáez, J, Pelizzoli, M, Parabicoli, S, Tomatis, S, Loiacono, D, Scorsetti, M, Mancosu, P. 01/06/2023. Physica Medica-European Journal Of Medical Physics. 110. PMID: 37104920. doi: 10.1016/j.ejmp.2023.102593

    Exploring the circulatory metabolic alterations in breast cancer patients

    Franco, AJ, Tomàs, ER, Lluis, CP, Vilafranca, HC, Gaya, GB, Araguas, P, Malave, B, Calderón, D, Acosta, JC, Arquez, M, Benavides, R, Riu, F, De la Flor, M, Jordà, C, Melé, M, Repkova, J, Sabater, S, Camps, J, Joven, J, Arenas, M. 01/05/2023. Radiotherapy And Oncology. 182

    Management of high-risk and post-operative non-metastatic prostate cancer in Catalonia: an expert Delphi consensus

    Bonet, M, González, D, Baquedano, JE, García, E, Altabas, M, Casas, F, Feltes, N, Ferrer, F, Foro, P, Fuentes, R, Galdeano, M, Gomez, D, Henriquez, I, Jové, J, Lozano, J, Maldonado, X, Mases, J, Membrive, I, Paredes, S, Roselló, A, Sancho, G, Mira, M. 01/04/2023. Clinical & Translational Oncology. 25. PMID: 36436177. doi: 10.1007/s12094-022-03005-4

    SARS-CoV-2 Serum Viral Load and Prognostic Markers Proposal for COVID-19 Pneumonia in Low-Dose Radiation Therapy Treated Patients

    Piqué, B, Peña, K, Riu, F, Acosta, JC, Torres-Royo, L, Malave, B, Araguas, P, Benavides, R, De Febrer, G, Camps, J, Joven, J, Arenas, M, Parada, D. 01/02/2023. Journal of clinical medicine. 12. PMID: 36769445. doi: 10.3390/jcm12030798

    Serum Arylesterase, Paraoxonase, and Lactonase Activities and Paraoxonase-1 Concentrations in Morbidly Obese Patients and Their Relationship with Non-Alcoholic Steatohepatitis

    Castañe, H, Jiménez-Franco, A, Martínez-Navidad, C, Placed-Gallego, C, Cambra-Cortés, V, Perta, AM, París, M, Castillo, DD, Arenas, M, Camps, J, Joven, J. 01/12/2023. Antioxidants. 12. PMID: 38136158. doi: 10.3390/antiox12122038

    Is irradiation of the primary tumor indicated in stage IV?

    Malave, B, Escuin, C, Arquez, M, Engel, O, Castaño, F, Arenas, M. 01/10/2023. Revista De Senologia Y Patologia Mamaria. 36. doi: 10.1016/j.senol.2023.100512

    Interventional Radiotherapy in Gynecological Cancer

    Rovirosa, A, Arenas, M, Tagliaferri, L. 01/10/2023. Cancers. 15. PMID: 37835498. doi: 10.3390/cancers15194804

    Immunotherapy and Hypofractionated Radiotherapy in Older Patients with Locally Advanced Cutaneous Squamous-Cell Carcinoma of the Head and Neck: A Proposed Paradigm by the International Geriatric Radiotherapy Group

    Nguyen, NP, Thariat, J, Gorobets, O, Vinh-Hung, V, Kim, L, Blanco, SC, Vasileiou, M, Arenas, M, Mazibuko, T, Giap, H, Vincent, F, Chi, A, Loganadane, G, Mohammadianpanah, M, Rembielak, A, Karlsson, U, Ali, A, Bose, S, Page, BR. 01/10/2023. Cancers. 15. PMID: 37894347. doi: 10.3390/cancers15204981

    Universal evaluation of MLC models in treatment planning systems based on a common set of dynamic tests

    Saez, J, Bar-Deroma, R, Bogaert, E, Cayez, R, Chow, T, Clark, CH, Esposito, M, Feygelman, V, Monti, AF, -Miguel, JG, Gershkevitsh, E, Goossens, J, Herrero, C, Hussein, M, Khamphan, C, Kierkels, RGJ, Lechner, W, Lemire, M, Nevelsky, A, Nguyen, D, Paganini, L, Pasler, M, Azorín, JFP, Garcia, LIR, Russo, S, Shakeshaft, J, Vieillevigne, L, Hernandez, V. 01/09/2023. Radiotherapy And Oncology. 186. PMID: 37385376. doi: 10.1016/j.radonc.2023.109775

    Treatment of COVID-19 pneumonia with low-dose radiotherapy plus standard of care versus standard of care alone in frail patients The SEOR-GICOR IPACOVID comparative cohort trial

    Arenas, M, Piqué, B, Torres-Royo, L, Acosta, JC, Rodríguez-Tomàs, E, De Febrer, G, Vasco, C, Araguas, P, Gómez, JA, Malave, B, Arquez, M, Algara, M, Montero, A, Montero, M, Simó, JM, Gabaldó, X, Parada, D, Riu, F, Sabater, S, Camps, J, Joven, J. 01/09/2023. Strahlentherapie Und Onkologie. 199. PMID: 37000224. doi: 10.1007/s00066-023-02067-9

    LDR brachytherapy offers superior tumor control to single-fraction HDR prostate brachytherapy: A prospective study

    Jimenez-Garcia, IE, Sabater, S, Martinez-Gutierrez, R, Sanchez-Galiano, P, Berenguer-Serrano, R, Castro-Larefors, S, Rey-Lopez, I, Ruiz-Herrero, B, Sánchez-Prieto, R, Rovirosa, A, Arenas, M, Gonzalez-Suarez, HA. 01/08/2023. Prostate. 83. PMID: 37150842. doi: 10.1002/pros.24548

    Matrix Metalloproteinase-9 Expression Is Associated with the Absence of Response to Neoadjuvant Chemotherapy in Triple-Negative Breast Cancer Patients

    Lejeune, M, Reverté, L, Gallardo, N, Sauras, E, Bosch, R, Mata, D, Roso, A, Petit, A, Peg, V, Riu, F, Garcia-Fontgivell, J, Relea, F, Vieites, B, de la Cruz-merino, L, Arenas, M, Rodriguez, V, Galera, J, Korzynska, A, Plancoulaine, B, Alvaro, T, López, C. 01/07/2023. International Journal Of Molecular Sciences. 24. PMID: 37511057. doi: 10.3390/ijms241411297

    Treatment of COVID-19 pneumonia with low-dose radiotherapy in frail patients

    Chacon, BAM, Arteaga, JCA, Piqué, B, Torres-Royo, L, Rodríguez-Tomás, E, Benavides, R, De Febrer, G, Araguas, P, Gomez, JA, Arquez, M, Calderon, VD, Algara, M, Montero, A, Parada, D, Riu, F, Jiménez, A, Vasco, C, Sabater, S, Camps, J, Joven, J, Prat, MA. 01/05/2023. Radiotherapy And Oncology. 182

    Radiotherapy treatment in non melanoma skin cancer (NMSC)

    Pianetta, MA, Pinel, MA, Castejín, AE, Gomez, DG, Murcia, M, Zuleta, FAC, López, Y, Trilla, J, Chacón, BM, Calderón, D, Royo, LT, Troncho, CE, Engel, O, Santafé, A, Mora, PA, Arteaga, JA, Martínez, FR, Prat, MA. 01/05/2023. Radiotherapy And Oncology. 182

    Recommendation on the technical and dosimetric data to be included in stereotactic body radiation therapy clinical trial publications based on a systematic review

    Josipovic, M, Hardcastle, N, Clementel, E, Gober, M, Wilke, L, Eaton, D, Hernandez, V, Saez, J, Smyth, G, Vieillevigne, L, Jornet, N, Mancosu, P. 01/05/2023. Radiotherapy And Oncology. 182

    Pattern of brain metastases after HA-PCI and SRCF in SCLC: pooled findings of NCT01780675 and PREMER

    Zeng, H, Schagen, S, Hendriks, L, Sánchez-Benavides, G, Jaspers, J, Manero, R, Lievens, Y, Murcia-Mejía, M, Kuenen, M, Rico-Oses, M, de Ruiter, M, Counago, F, Dieleman, E, de Jaeger, K, Calvo-Crespo, P, Lambrecht, M, Samper, P, Belderbos, J, De Ruysscher, D, de Dios, NR. 01/05/2023. Radiotherapy And Oncology. 182

    Prognostic Implications of the Residual Tumor Microenvironment after Neoadjuvant Chemotherapy in Triple-Negative Breast Cancer Patients without Pathological Complete Response

    Lejeune, M, Reverté, L, Sauras, E, Gallardo, N, Bosch, R, Roso, A, Petit, A, Peg, V, Riu, F, García-Fontgivell, J, Ibáñez, J, Relea, F, Vieites, B, Bor, C, de la Cruz-Merino, L, Arenas, M, Rodriguez, V, Galera, J, Korzynska, A, Belhomme, P, Plancoulaine, B, Alvaro, T, López, C. 01/02/2023. Cancers. 15. PMID: 36765559. doi: 10.3390/cancers15030597

    Combining Dietary Intervention with Metformin Treatment Enhances Non-Alcoholic Steatohepatitis Remission in Mice Fed a High-Fat High-Sucrose Diet

    Baiges-Gaya, G, Rodríguez-Tomàs, E, Castañé, H, Jiménez-Franco, A, Amigó, N, Camps, J, Joven, J. 01/12/2022. Biomolecules. 12. PMID: 36551216. doi: 10.3390/biom12121787

    Gradient Boosting Machine Identified Predictive Variables for Breast Cancer Patients Pre- and Post-Radiotherapy: Preliminary Results of an 8-Year Follow-Up Study

    Rodríguez-Tomàs, E, Arenas, M, Baiges-Gaya, G, Acosta, J, Araguas, P, Malave, B, Castañé, H, Jiménez-Franco, A, Benavides-Villarreal, R, Sabater, S, Solà-Alberich, R, Camps, J, Joven, J. 01/12/2022. Antioxidants. 11. PMID: 36552602. doi: 10.3390/antiox11122394

    Challenges in modeling the Agility multileaf collimator in treatment planning systems and current needs for improvement

    Hernandez, V, Angerud, A, Bogaert, E, Hussein, M, Lemire, M, García-Miguel, J, Saez, J. 01/12/2022. Medical Physics. 49. PMID: 36217283. doi: 10.1002/mp.16016

    Automatic planning of the lower extremities for total marrow irradiation using volumetric modulated arc therapy

    Lambri, N, Dei, D, Hernandez, V, Castiglioni, I, Clerici, E, Crespi, L, De Philippis, C, Loiacono, D, Navarria, P, Reggiori, G, Rusconi, R, Tomatis, S, Bramanti, S, Scorsetti, M, Mancosu, P. 03/11/2022. Strahlentherapie Und Onkologie. 199. PMID: 36326856. doi: 10.1007/s00066-022-02014-0

    Rate of effect of surgical margins after breast conserving surgery and estimation of direct costs

    De la Flor, M, Delgado, C, Martínez, S, Arenas, M, Gómez, M, Reig, R. 01/11/2022. Cirugia Espanola. 100

    Measurement of Plasma Galectin-3 Concentrations in Patients with Catheter Infections: A Post Hoc Retrospective Cohort Study

    Iftimie, S, Hernández-Aguilera, A, López-Azcona, AF, Castañé, H, Rodríguez-Tomàs, E, Baiges-Gaya, G, Camps, J, Castro, A, Joven, J. 01/10/2022. Diagnostics. 12. PMID: 36292107. doi: 10.3390/diagnostics12102418

    Treatment of non-metastatic castration-resistant prostate cancer: facing age-related comorbidities and drug-drug interactions

    Conde-Estevez, D, Henriquez, I, Munoz-Rodriguez, J, Rodriguez-Vida, A. 02/09/2022. Expert Opinion On Drug Metabolism & Toxicology. 18. PMID: 36111393. doi: 10.1080/17425255.2022.2122812

    SALVAGE PROSTATE BRACHYTHERAPY IN RADIORECURRENT PROSTATE CANCER: AN INTERNATIONAL DELPHI CONSENSUS STUDY

    Morton, G, Chung, HT, Corkum, MT, Buyyounouski, M, Chang, A, Chung, P, Cox, B, Crook, J, Davis, B, Frank, S, Henriquez, I, Horwitz, E, Hoskin, P, Hsu, IC, Keyes, M, King, M, Kollmeier, M, Krauss, D, Kukielka, A, Orio, P, Pieters, B, Potters, L, Rossi, P, Showalter, T, Solanki, A, Song, D, Vanneste, B, Vigneault, E, Wojcieszek, P, Zelefsky, M, Kamrava, M. 01/09/2022. Radiotherapy And Oncology. 174

    Ways to improve breast cancer patients' management and clinical outcome: The 2020 Assisi Think Tank Meeting

    Aristei, C, Bolukbasi, Y, Kaidar-Person, O, Pfeffer, R, Arenas, M, Boersma, LJ, Ciabattoni, A, Coles, CE, Franco, P, Krengli, M, Leonardi, MC, Marazzi, F, Masiello, V, Meattini, I, Montero, A, Offersen, B, Trigo, ML, Bourgier, C, Genovesi, D, Kouloulias, V, Morganti, AG, Meduri, B, Pasinetti, N, Pedretti, S, Perrucci, E, Rivera, S, Tombolini, V, Vidali, C, Valentini, V, Poortmans, P. 01/09/2022. Critical Reviews In Oncology Hematology. 177. PMID: 35917884. doi: 10.1016/j.critrevonc.2022.103774

    Investigation on the impact of the leaf trailing effect using the Halcyon integrated platform system

    Azorín, JFP, Saez, J, Garcia, LIR, Hernandez, V. 01/09/2022. Medical Physics. 49. PMID: 35770385. doi: 10.1002/mp.15833

    Plan quality assessment in clinical practice: Results of the 2020 ESTRO survey on plan complexity and robustness

    Kaplan, LP, Placidi, L, Bäck, A, Canters, R, Hussein, M, Vaniqui, A, Fusella, M, Piotrowski, T, Hernandez, V, Jornet, N, Hansen, CR, Widesott, L. 01/08/2022. Radiotherapy And Oncology. 173. PMID: 35714808. doi: 10.1016/j.radonc.2022.06.005

    Evidence-based guidelines for hypofractionated radiation in breast cancer: conclusions of the Catalan expert working group

    Eraso, A, Sanz, J, Mollà, M, Reyes, V, Pedro, A, Arenas, M, Martinez, E, Ballester, R, Cambra, MJ, García, V, Prades, JL, Borras, JM, Algara, M. 01/08/2022. Clinical & Translational Oncology. 24. PMID: 35190961. doi: 10.1007/s12094-022-02798-8

    Usefulness of the Measurement of Serum Paraoxonase-1 Arylesterase Activity in the Diagnoses of COVID-19

    Gabaldó, X, Juanpere, M, Castañé, H, Rodríguez-Tomàs, E, López-Azcona, AF, Baiges-Gaya, G, Castro, L, Valverde-Díaz, E, Muñoz-Blázquez, A, Giménez-Cuenca, L, Felipo-Balada, L, Ballester, F, Pujol, I, Simó, JM, Castro, A, Iftimie, S, Camps, J, Joven, J. 01/07/2022. Biomolecules. 12. PMID: 35883435. doi: 10.3390/biom12070879

    Phospholipid fingerprints reveal sex differences in the adipose tissue phospholipid composition from morbidly obese patients

    Baiges, G, Rodríguez-Tomàs, E, Castañé, H, Franco, AJ, Camps, J, Joven, J. 01/07/2022. Journal Of Hepatology. 77

    Lipidomics and proteomics reveal mitochondrial dysfunction in liver and visceral adipose tissue from patients with non-alcoholic steatohepatitis

    Castañé, H, Franco, AJ, Rodríguez-Tomàs, E, Gaya, GB, Camps, J, Joven, J. 01/07/2022. Journal Of Hepatology. 77

    Laparoscopic Sleeve Gastrectomy in Patients with Severe Obesity Restores Adaptive Responses Leading to Nonalcoholic Steatohepatitis

    Cabré, N, Luciano-Mateo, F, Chapski, DJ, Baiges-Gaya, G, Fernández-Arroyo, S, Hernández-Aguilera, A, Castañé, H, Rodríguez-Tomàs, E, París, M, Sabench, F, Del Castillo, D, del Bas, JM, Tomé, M, Bodineau, C, Sola-García, A, López-Miranda, J, Martín-Montalvo, A, Duran, RV, Vondriska, TM, Rosa-Garrido, M, Camps, J, Menéndez, JA, Joven, J. 01/07/2022. International Journal Of Molecular Sciences. 23. PMID: 35887177. doi: 10.3390/ijms23147830

    Carnitine signature in liver corretales with non-alcoholic fatty liver disease progression

    Franco, AJ, Castañe, H, Gaya, GB, Rodríguez-Tomas, E, Andreu, JC, Maried, JJ. 01/07/2022. Journal Of Hepatology. 77

    Hepatic lipid fingerprint reveals sex-dependent lipid droplet composition in metabolic associated fatty liver disease

    Rodríguez-Tomàs, E, Gaya, GB, Castañe, H, Franco, AJ, Andreu, JC, Maried, JJ. 01/07/2022. Journal Of Hepatology. 77

    CD68 and CD83 immune populations in non-metastatic axillary lymph nodes are of prognostic value for the survival and relapse of breast cancer patients

    López, C, Bosch, R, Korzynska, A, García-Rojo, M, Bueno, G, García-Fontgivell, JF, González, SM, Navarro, AG, Colón, ES, Ribes, JC, Roszkowiak, L, Mata, D, Arenas, M, Gómez, J, Roso, A, Berenguer, M, Reverté-Villarroya, S, Llobera, M, Baucells, J, Lejeune, M. 01/07/2022. Breast Cancer. 29. PMID: 35137329. doi: 10.1007/s12282-022-01336-2

    Effect of Low-Dose Radiotherapy on the Circulating Levels of Paraoxonase-1-Related Variables and Markers of Inflammation in Patients with COVID-19 Pneumonia

    Rodríguez-Tomàs, E, Acosta, JC, Torres-Royo, L, De Febrer, G, Baiges-Gaya, G, Castañé, H, Jiménez, A, Vasco, C, Araguas, P, Gómez, J, Malave, B, Arquez, M, Calderón, D, Piqué, B, Algara, M, Montero, A, Simó, JM, Gabaldó-Barrios, X, Sabater, S, Camps, J, Joven, J, Arenas, M. 01/06/2022. Antioxidants. 11. PMID: 35740079. doi: 10.3390/antiox11061184

    Machine learning and semi-targeted lipidomics identify distinct serum lipid signatures in hospitalized COVID-19-positive and COVID-19-negative patients

    Castañé, H, Iftimie, S, Baiges-Gaya, G, Rodríguez-Tomás, E, Jiménez-Franco, A, López-Azcona, AF, Garrido, P, Castro, A, Camps, J, Joven, J. 01/06/2022. Metabolism-Clinical And Experimental. 131. PMID: 35381232. doi: 10.1016/j.metabol.2022.155197

    Clinical Outcome and Radiologic Changes in SARS-CoV-2 Pneumonia treated with Low-Dose Radiotherapy.

    Arteaga, JCA, Royo, LT, Rodríguez-Tomás, E, De Febrer, G, Vasco, C, Gomez, JA, Araguas, P, Malave, B, Arquez, M, Algara, M, Montero, A, Montero, M, Simo, JM, Gavaldà, X, Pique, B, Parada, D, Sabater, S, Camps, J, Joven, J, Arenas, M. 01/05/2022. Radiotherapy And Oncology. 170

    GOECP/SEOR radiotheraphy guidelines for non-small-cell lung cancer

    De Dios, NR, Navarro-Martin, A, Cigarral, C, Chicas-Sett, R, Garcia, R, Garcia, V, Gonzalez, JA, Gonzalo, S, Murcia-Mejia, M, Robaina, R, Sotoca, A, Vallejo, C, Valtuena, G, Counago, F. 24/04/2022. World Journal Of Clinical Oncology. 13. PMID: 35582651. doi: 10.5306/wjco.v13.i4.237

    Anticipating metastasis through electrochemical immunosensing of tumor hypoxia biomarkers

    Muñoz-San Martín, C, Gamella, M, Pedrero, M, Montero-Calle, A, Pérez-Ginés, V, Camps, J, Arenas, M, Barderas, R, Pingarrón, JM, Campuzano, S. 01/01/2022. Analytical And Bioanalytical Chemistry. 414. PMID: 33635388. doi: 10.1007/s00216-021-03240-8

    Impact of the dose quantity used in MV photon optimization on dose distribution, robustness, and complexity

    Jurado-Bruggeman, D, Muñoz-Montplet, C, Hernandez, V, Saez, J, Fuentes-Raspall, R. 01/01/2022. Medical Physics. 49. PMID: 34855988. doi: 10.1002/mp.15389

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