Presentació dels Hospitals
Col·labora

Sepsis, Inflamació i Seguretat del Malalt Crític (SIS)

INFECCIÓ, IMMUNITAT I MEDI AMBIENT
SEPSIS MALALTIES INFECCIOSES TOXICOLOGIA MICROBIOLOGIA
OBJECTIUS

El grup SIS està constituït per un nucli de 10 investigadors doctors y 20 investigadors clínics multidisciplinari que coincideixen en interessos i línies de recerca i que estan desenvolupant conjuntament nous projectes en l’àmbit de la sèpsia, la inflamació, la seguretat en el malalt crític i anàlisis de dades en salut (BIG-DATA i Machine Learning).

RESPONSABLES

  • Dra. María Bodí

  • Dr. Alejandro Rodriguez Oviedo

  • Presentació
  • Línies de recerca
  • Transferència
  • Membres del grup
  • Projectes
  • Difusió
  • Publicacions
  • Contacte

María Bodí i Alejandro Rodríguez (responsables del grup) són membres del CIBERes (ISCIII) node 14 (IP Dr. Antoni Torres). El grup s’estructura al voltant d’un investigador responsable (María Bodí) que és professora associada de la URV, Cap del Servei de Medicina Intensiva de l’HJ23 i Coordinadora Territorial de Trasplantaments de la província de Tarragona i  Alejandro Rodriguez, també professor associat de la URV i Coordinador Nacional del registre de Grip Greu /COVID-19 de la SEMICYUC.

Al llarg d’aquests darrers anys com a Grup de Recerca Consolidat (AGAUR) s’han pogut consolidar les diferents línies de recerca del Grup a través un gran número de projectes competitius nacionals i internacionals, i s’ha consolidat una línea d’investigació en dades de salut amb la incorporació de 4 científics de dades. El grup SIS té una elevada producció científica amb més de 70 punts de factor d’impacte per any.

  • Sèpsia: Epidemiologia general i molecular
  • Diagnòstic, prevenció i tractament
  • Inflamació, hipòxia i alteracions macro i microcirculatorias
  • Seguretat del pacient crític
  • Donació i Trasplantament
  • Sistemes TIC, qualitat, seguretat de l’pacient crític
  • Anàlisi de dades en salut, Big Data i Machine Learning

  • ICU-DaMa: (Intesive care Data Management) iDEPOT 102487

  • AASTRE: (Análisis Aleatorios de Seguridad en Tiempo Real) T-0629-2012

  • Títol: Informacion, comunicacion y trabajo en equipo en medicina intensiva: Analisis Aleatorios de Seguridad en Tiempo Real relacionados con los sic y la traslacion conocmiento (AAESTRE-SIC)

    Òrgan finançador: Instituto de Salud Carlos III
    Any: 2016 – 2019

    Referència: PI16/00491

  • Títol: Daño miocardico en la neumonia neumococica grave como causa de mortalidad por eventos cardiovasculares agudos (NEUMOCAR)

    Òrgan finançador: Instituto de Salud Carlos III
    Any: 2017 – 2021

    Referència: PI16/00486

  • Title: Información, comunicación y trabajo en equipo en medicina intensiva: análisis aleatorios de seguridad en tiempo real realcionados con los SIC y la traslación conomimiento (AAESTRE-SIC) PI16/00491.

    Funding entity: Instituto de Salud Carlos III

    Duration: 2017 -2021

    Principal Investigator: María Bodí Saera

  • Title: 2017 SGR 00127 Suport a Grups de Recerca (SGR) IISPV-Fundació Salut (Consorci Sanitària del Maresme) Finançament- Grup de Recerca consolidat

    Funding entity: Ajuts SGR

    Duration: 2017 -2021

    Principal Investigator: María Bodí Saera

    Año

    Mid-Regional Pro-Adrenomedullin as a Translational Biomarker of Microcirculatory Dysfunction in Sepsis: A Prospective Observational Study.

    Cusack R, Garduno A, Cumpf S, Reyes-Morales P, Leone M, Fernández AB, Rodriguez A, Martin-Loeches I. 02/03/2026. Medical Sciences (basel, Switzerland). 14. PMID: 41892832. doi: 10.3390/medsci14010117

    Authors reply: "Microcirculation properties of 20 % albumin in Sepsis; a randomised controlled trial".

    Cusack R, Rodríguez A, Cantan B, Garduno A, Connolly E, Zilahi G, Coakley JD, Martin-Loeches I. 01/02/2026. Journal Of Critical Care. 91. PMID: 41037879. doi: 10.1016/j.jcrc.2025.155279

    Influence of the Molecular Subtype-Dependent Immune Microenvironment of Metastatic Axillary Lymph Nodes on Breast Cancer Patient Outcomes.

    López C, Reverté L, Bosch Príncep R, Sauras E, Gallardo-Borràs N, Fischer-Carles A, Korzynska A, García-Rojo M, Bueno G, Roszkowiak L, Roso-LLorach A, Gras Navarro A, Llobera M, Mata D, Adalid Llansa L, Martínez-González S, Garcia-Fontgivell JF, Arenas M, Gómez J, Izuel JA, Baucells J, Lejeune M. 31/12/2025. Pathobiology. PMID: 41474659. doi: 10.1159/000550086

    Ventilator-Associated Pneumonia (VAP) in Neurocritical Patients: The Hidden Dialog of Brain and Infection

    Rodríguez, A, Claverias, L, Martín-Loeches, I, Bertomeu, FG, Plana, EP, Rosich, S, Blázquez, V, Torrez, DHC, Lau, R, Bodí, M. 17/12/2025. Biomedicines. 13. PMID: 41463120. doi: 10.3390/biomedicines13123112

    Association Between Methylprednisolone and the Increase of Respiratory Infections in COVID-19 Patients in the Intensive Care Unit

    Tuta-Quintero, E, Bastidas, A, García-Gallo, E, Díaz, E, Bodí, M, Solé-Violán, J, Ferrer, R, Albaya-Moreno, A, Socias, L, Estella, A, Loza-Vazquez, A, Jorge-García, R, Sancho, I, Martin-Loeches, I, Rodriguez, A, Reyes, LF. 08/12/2025. Covid. 5. doi: 10.3390/covid5120204

    Early identification of hypofibrinogenemia in major trauma: The usefulness of the FiT-6 (Fibrinogen in Trauma-6) score.

    Ruiz-Bocos Á, Sirgo G, Cartanyà M, Canelles S, Urgelés S, Daniel X, Murillo N, Berrueta J, Aguinaco R, Bodí M, Rodríguez A, Moreno G. 01/12/2025. Medicina Intensiva. 49. PMID: 41184162. doi: 10.1016/j.medine.2025.502296

    Authors reply: "Microcirculation properties of 20 % albumin in sepsis; a randomised controlled trial".

    Cusack RAF, Cantan B, Garduno A, Rodríguez A, Connolly E, Zilahi G, Coakley JD, Martin-Loeches I. 01/12/2025. Journal Of Critical Care. 90. PMID: 40684603. doi: 10.1016/j.jcrc.2025.155173

    Management of endothelial dysfunction in septic shock: role of albumin administration.

    Martin-Loeches I, Rodríguez A, Russell L, Chew MS, Einav S, Conway Morris A, Leone M. 27/11/2025. Journal of intensive care. 14. PMID: 41310901. doi: 10.1186/s40560-025-00836-5

    Immunosuppressed patients with COVID-19 pneumonia in ICU: clinical characteristics and factors influencing outcomes

    Galli, F, Forin, E, Motos, A, Saldarriaga, FJM, Gabarrus, A, Canseco, J, Fernandez-Barat, L, Barbeta, E, Calabretta, D, Ceccato, A, Bermejo-Martin, JF, Ferrer, R, Riera, J, Penuelas, O, Lorente, JA, de Gonzalo-Calvo, D, Menendez, R, Gonzalez, J, Palomeque, A, Soler-Comas, A, Amaya-Villar, R, Anon, JM, Marino, AB, Barbera, C, Barberan, J, Ortiz, AB, Bustamante-Munguira, E, Caballero, J, Canton-Bulnes, ML, Perez, CC, Carbonell, N, Catalan-Gonzalez, M, De Frutos, R, Franco, N, Galban, C, Lago, AL, Gumucio-Sanguino, VD, de la Torre, MD, Diaz, E, Estella, A, Curto, EG, Garcia-Garmendia, JL, Gomez, JM, Huerta, A, Garcia, RNJ, Loza-Vazquez, A, Marin-Corral, J, Delgado, MCM, de la Gandara, AM, Varela, IM, Messa, JL, Albaiceta, GM, Nieto, MT, Novo, MA, Penasco, Y, Perez-Garcia, F, Pozo-Laderas, JC, Ricart, P, Sagredo, V, Sanchez-Miralles, A, Chinesta, SS, Roche-Campo, F, Socias, L, Sole-Violan, J, Suarez-Sipmann, F, Lomas, LT, Trenado, J, Ubeda, A, Valdivia, LJ, Vidal, P, Boado, MV, Rodriguez, A, Ferrer, M, Barbe, F, Torres, A. 25/11/2025. PNEUMONIA. 17. PMID: 41287034. doi: 10.1186/s41479-025-00181-z

    Impact of statins on short and long term mortality in severe community acquired pneumonia in the intensive care unit.

    Olivella-Gomez J, Sanabria-Herrera N, Garcia-Gallo E, Duque S, Luna D, Oliveros H, Morris AC, Rodriguez A, Annane D, Martin-Loeches I, Reyes LF. 21/11/2025. Scientific Reports. 15. PMID: 41271854. doi: 10.1038/s41598-025-25066-5

    Reformulating real-time random safety analysis during the SARS-CoV-2 pandemic

    Sirgo, G, Samper, MA, Berrueta, J, Cañellas, J, Rodríguez, A, Bodí, M. 01/09/2025. Medicina Intensiva. 49. PMID: 39734115. doi: 10.1016/j.medin.2024.502117

    Meropenem and piperacillin/tazobactam optimised dosing regimens for critically ill patients receiving renal replacement therapy.

    Roberts JA, Ulldemolins M, Liu X, Baptista JP, Bilgrami I, Boidin C, Brinkmann A, Castro P, Choi G, Cole L, De Waele JJ, Deans R, Donnellan S, Eastwood GM, Frey OR, Goutelle S, Gresham R, Jamal JA, Joynt GM, Kanji S, Kluge S, König C, Koulouras VP, Lassig-Smith M, Laterre PF, Lee A, Lefrant JY, Lei K, Leung P, Llaurado-Serra M, Martin-Loeches I, Nor MBM, Mudaliar Y, Ostermann M, Paul SK, Peake SL, Rello J, Roberts DM, Roberts MS, Richards B, Rodríguez A, Roehr AC, Roger C, Seoane L, Sinnollareddy M, Sousa E, Soy D, Spring A, Starr T, Stephens D, Taccone FS, Thomas J, Turnidge J, Valkonen M, Varghese JM, Wallis SC, Walker RJ, Williams T, Wilson LC, Wittebole X, Wright DFB, Zikou XT, Bellomo R, Lipman J. 01/09/2025. Intensive Care Medicine. 51. PMID: 40801954. doi: 10.1007/s00134-025-08067-w

    Re-explaining patient safety in Intensive Care Medicine: In need of understanding and action.

    Martín Delgado MC, Chico Fernández M, Sirgo Rodríguez G, Bodí M. 01/09/2025. Medicina Intensiva. 49. PMID: 40581495. doi: 10.1016/j.medine.2025.502219

    Machine Learning-Based Identification of Risk Factors for ICU Mortality in 8902 Critically Ill Patients with Pandemic Viral Infection.

    Papiol E, Ferrer R, Ruiz-Rodríguez JC, Díaz E, Zaragoza R, Borges-Sa M, Berrueta J, Gómez J, Bodí M, Sancho S, Suberviola B, Trefler S, Rodríguez A. 30/07/2025. Journal of clinical medicine. 14. PMID: 40807005. doi: 10.3390/jcm14155383

    Severe community-acquired pneumonia (sCAP): advances in management and future directions.

    Martin-Loeches I, Reyes LF, Rodriguez A. 15/07/2025. Thorax. 80. PMID: 40360263. doi: 10.1136/thorax-2024-222296

    Albumin Enhances Microvascular Reactivity in Sepsis: Insights from Near-Infrared Spectroscopy and Vascular Occlusion Testing.

    Cusack R, Rodríguez A, Cantan B, Miskolci O, Connolly E, Zilahi G, Coakley JD, Martin-Loeches I. 14/07/2025. Journal of clinical medicine. 14. PMID: 40725675. doi: 10.3390/jcm14144982

    Longitudinal analysis of lung microbiome, immune response, and metabolism in ventilator-associated pneumonia: a cohort study

    Bustos, IG, Serrano-Mayorga, CC, Guerrero, JL, Baker, JM, Brown, C, Falkowski, N, Ranjan, P, Acosta-Gonzalez, A, Mendez, LM, Garcia-Cordoba, A, Echeverry-Gutierrez, A, Bojaca, DA, Chisica-Mahecha, M, Guarin-Tequia, N, Romero-Romero, L, Gonzalez-Juarbe, N, Rodriguez, A, Cala, MP, Martin-Loeches, I, Chotirmall, SH, Dickson, RP, Reyes, LF. 03/07/2025. Critical Care. 29. PMID: 40611327. doi: 10.1186/s13054-025-05498-1

    Combining Predictive Models of Mortality and Time-to-Discharge for Improved Outcome Assessment in Intensive Care Units.

    Pardo À, Gómez J, Berrueta J, García A, Manrique S, Rodríguez A, Bodí M. 25/06/2025. Journal of clinical medicine. 14. PMID: 40648890. doi: 10.3390/jcm14134515

    Does Empirical Antibiotic Use Improve Outcomes in Ventilated Patients with Pandemic Viral Infection? A Multicentre Retrospective Study.

    Papiol E, Berrueta J, Ruíz-Rodríguez JC, Ferrer R, Manrique S, Claverias L, García-Martínez A, Orts P, Díaz E, Zaragoza R, Marotta M, Bodí M, Trefler S, Gómez J, Martín-Loeches I, Rodríguez A. 08/06/2025. Antibiotics-Basel. 14. PMID: 40558184. doi: 10.3390/antibiotics14060594

    Microcirculation properties of 20 % albumin in sepsis; a randomised controlled trial.

    Cusack RAF, Rodríguez A, Cantan B, Garduno A, Connolly E, Zilahi G, Coakley JD, Martin-Loeches I. 01/06/2025. Journal Of Critical Care. 87. PMID: 40020556. doi: 10.1016/j.jcrc.2025.155039

    Nosocomial lower respiratory tract infections in patients with immunosuppression: a cohort study.

    Reyes LF, Sanabria-Herrera N, Nseir S, Ranzani OT, Povoa P, Diaz E, Schultz MJ, Rodríguez A, Serrano-Mayorga CC, De Pascale G, Navalesi P, Skoczynski S, Esperatti M, Coelho LM, Cortegiani A, Aliberti S, Caricato A, Salzer HJF, Ceccato A, Civljak R, Soave PM, Luyt CE, Ekren PK, Rios F, Masclans JR, Marin J, Iglesias-Moles S, Nava S, Chiumello D, Bos LDJ, Artigas A, Froes F, Grimaldi D, Panigada M, Taccone FS, Antonelli M, Torres A, Martin-Loeches I. 06/05/2025. Annals of Intensive Care. 15. PMID: 40328994. doi: 10.1186/s13613-025-01462-y

    Preliminary results of the implementation of a Complex Surgical Patient Area as a tool to improve the quality of care.

    Pavel MC, Ferre A, Garcia-Huete L, Oliva I, Guillem L, Tomas I, Renzulli M, Jorba-Martin R. 01/05/2025. Cirugia Espanola. 103. PMID: 40010565. doi: 10.1016/j.cireng.2025.02.005

    Current Perspectives on the Use of Artificial Intelligence in Critical Patient Safety

    Mendoza, JAB, Fernandez, MV, Fernandez, AP, Alvarez, JG. 01/03/2025. Medicina Intensiva. 49. PMID: 38677902. doi: 10.1016/j.medin.2024.03.007

    A consensus of European experts on the definition of ventilator-associated pneumonia recurrences obtained by the Delphi method: the RECUVAP study

    Gaillet, A, Luyt, CE, Timsit, JF, Asehnoune, K, Barbier, F, Bassetti, M, Bouadma, L, Bouglé, A, Chastre, J, Morris, AC, De Waele, JJ, Dépret, F, Dimopoulos, G, Ehrmann, S, Ewig, S, Fartoukh, M, Foucrier, A, Garnacho-Montero, J, Hraiech, S, Leone, M, Makris, D, Martin-Loeches, I, Matthaiou, D, Monsel, A, Montravers, P, Nseir, S, Paiva, JA, Papazian, L, Poulakou, G, Póvoa, P, Pugin, J, Rodriguez, AH, Roquilly, A, Roux, D, Rouzé, A, Taccone, FS, Torres, A, Zahar, JR, Weiss, E, Razazi, K. 01/03/2025. Intensive Care Medicine. 51. PMID: 40163131. doi: 10.1007/s00134-025-07856-7

    Mechanical power is not associated with mortality in COVID-19 mechanically ventilated patients

    Barbeta, E, Barreiros, C, Forin, E, Guzzardella, A, Motos, A, Fernández-Barat, L, Gabarrús, A, Ceccato, A, Ferrer, R, Riera, J, Peñuelas, O, Lorente, JA, de Gonzalo-Calvo, D, Gonzalez, J, Amaya-Villar, R, Añón, JM, Balan, A, Barberà, C, Barberán, J, Blandino, A, Boado, MV, Bustamante-Munguira, E, Caballero, J, Cantón-Bulnes, ML, Carbajales, C, Carbonell, N, Catalán-González, M, Franco, N, Galbán, C, Gumucio-Sanguino, VD, de la Torre, MD, Díaz, E, Estella, A, Gallego, E, Gómez, JM, Huerta, A, García, RNJ, Loza-Vázquez, A, Marin-Corral, J, Delgado, MCM, Martínez, A, Martínez, I, Lopez, J, Albaiceta, GM, Nieto, MT, Novo, MA, Peñasco, Y, Pérez-García, F, Ricart, P, Rodríguez, A, Sagredo, V, Sánchez-Miralles, A, Sancho, S, Roche-Campo, F, Socias, L, Solé-Violan, J, Tamayo, L, Trenado, J, Ubeda, A, Valdivia, LJ, Vidal, P, Barbé, F, Vallverdú, J, Torres, A. 25/02/2025. Annals of Intensive Care. 15. PMID: 39998751. doi: 10.1186/s13613-025-01430-6

    Ten-Year Evaluation of Ventilator-Associated Pneumonia (VAP) According to Initial Empiric Treatment: A Retrospective Analysis Using Real-World Data

    Rodríguez, A, Berrueta, J, Páez, C, Huertas, R, Marotta, M, Claverias, L, Gómez, J, Trefler, S, Bertomeu, FFG, Guerrero-Torres, MD, Pardo-Granell, S, Picó-Plana, E, Selles-Sánchez, A, Candel, FJ, Martín-Loeches, I, Bodí, M. 01/02/2025. Biomedicines. 13. PMID: 40002773. doi: 10.3390/biomedicines13020360

    Factors Associated with Mortality in Nosocomial Lower Respiratory Tract Infections: An ENIRRI Analysis.

    Reyes LF, Torres A, Olivella-Gomez J, Ibáñez-Prada ED, Nseir S, Ranzani OT, Povoa P, Diaz E, Schultz MJ, Rodríguez AH, Serrano-Mayorga CC, De Pascale G, Navalesi P, Skoczynski S, Esperatti M, Coelho LM, Cortegiani A, Aliberti S, Caricato A, Salzer HJF, Ceccato A, Civljak R, Soave PM, Luyt CE, Korkmaz Ekren P, Rios F, Masclans JR, Marin J, Iglesias-Moles S, Nava S, Chiumello D, Bos LD, Artigas A, Froes F, Grimaldi D, Panigada M, Taccone FS, Antonelli M, Martin-Loeches I. 26/01/2025. Antibiotics-Basel. 14. PMID: 40001371. doi: 10.3390/antibiotics14020127

    Risk factors and outcome of acute kidney injury in critically ill patients with SARS-CoV-2 pneumonia: a multicenter study.

    Oliva I, Ferré C, Daniel X, Cartanyà M, Villavicencio C, Salgado M, Vidaur L, Papiol E, de Molina FG, Bodí M, Herrera M, Rodríguez A. 01/01/2025. Medicina Intensiva. 49. PMID: 39003118. doi: 10.1016/j.medine.2024.06.022

    The role of rapid multiplex molecular syndromic panels in the clinical management of infections in critically ill patients: an experts-opinion document

    Candel, FJ, Salavert, M, Cantón, R, del Pozo, JL, Galán-Sánchez, F, Navarro, D, Rodríguez, A, Rodríguez, JC, Rodríguez-Aguirregabiria, M, Suberviola, B, Zaragoza, R. 30/12/2024. Critical Care. 28. PMID: 39736683. doi: 10.1186/s13054-024-05224-3

    Duration of severe and moderate symptoms in pharyngitis by cause

    Moragas, A, Sarvisé, C, Gómez, F, Picó-Plana, E, Crispi, S, Llor, C. 01/11/2024. Atencion Primaria. 56. PMID: 38875835. doi: 10.1016/j.aprim.2024.102994

    Impact of mechanical power on ICU mortality in ventilated critically ill patients: a retrospective study with continuous real-life data

    Manrique, S, Ruiz-Botella, M, Murillo, N, Canelles, S, Victoria, ID, Samper, MA, Plans, O, Claverias, L, Magret, M, Gordo, F, Roca, O, Bodí, M. 07/10/2024. European Journal Of Medical Research. 29. PMID: 39375738. doi: 10.1186/s40001-024-02082-1

    A Machine Learning Approach to Determine Risk Factors for Respiratory Bacterial/Fungal Coinfection in Critically Ill Patients with Influenza and SARS-CoV-2 Infection: A Spanish Perspective

    Rodríguez, A, Gómez, J, Martín-Loeches, I, Claverias, L, Díaz, E, Zaragoza, R, Borges-Sa, M, Gómez-Bertomeu, F, Franquet, A, Trefler, S, Garzón, CG, Cortés, L, Alés, F, Sancho, S, Solé-Violán, J, Estella, A, Berrueta, J, García-Martínez, A, Suberviola, B, Guardiola, JJ, Bodí, M. 01/10/2024. Antibiotics-Basel. 13. PMID: 39452234. doi: 10.3390/antibiotics13100968

    Prospective and External Evaluation of an Artificial Intelligence Model for Continuous and Early Prediction of Moderate and Severe AKI in Critically Ill Patients

    Kashani, K, Alfieri, F, Ancona, A, Zappalà, S, Votta, CD, Maderna, L, Gomez, J, Esteban, F, Gilavert, MC, Bodí, M, Finazzi, S, Bacci, A, Cauda, V. 01/10/2024. Journal Of The American Society Of Nephrology. 35. doi: 10.1681/ASN.2024y4e76zq7

    Advancing ICU patient care with a Real-Time predictive model for mechanical Power to mitigate VILI

    Ruiz-Botella, M, Manrique, S, Gomez, J, Bodí, M. 01/09/2024. INTERNATIONAL JOURNAL OF MEDICAL INFORMATICS. 189. PMID: 38851133. doi: 10.1016/j.ijmedinf.2024.105511

    A Real-World Data Observational Analysis of the Impact of Liposomal Amphotericin B on Renal Function Using Machine Learning in Critically Ill Patients

    Sacanella, I, Esteve-Pitarch, E, Guevara-Chaux, J, Berrueta, J, García-Martínez, A, Gómez, J, Casarino, C, Alés, F, Canadell, L, Martín-Loeches, I, Grau, S, Candel, FJ, Bodí, M, Rodríguez, A. 01/08/2024. Antibiotics-Basel. 13. PMID: 39200060. doi: 10.3390/antibiotics13080760

    A targeted likelihood estimation comparing cefepime and piperacillin/tazobactam in critically ill patients with community-acquired pneumonia (CAP)

    Serrano-Mayorga, CC, Duque, S, Ibanez-Prada, ED, Garcia-Gallo, E, Arrieta, MPR, Bastidas, A, Rodriguez, A, Martin-Loeches, I, Reyes, LF. 11/06/2024. Scientific Reports. 14. PMID: 38862579. doi: 10.1038/s41598-024-64444-3

    Hospital-acquired bacterial pneumonia in critically ill patients: from research to clinical practice

    Kouroupis, PC, O’Rourke, N, Kelly, S, McKittrick, M, Noppe, E, Reyes, LF, Rodriguez, A, Martin-Loeches, I. 02/06/2024. Expert Review Of Anti-Infective Therapy. 22. PMID: 38743435. doi: 10.1080/14787210.2024.2354828

    Applicability of an unsupervised cluster model developed on first wave COVID-19 patients in second/third wave critically ill patients

    Rodríguez, A, Gómez, J, Franquet, A, Trefler, S, Díaz, E, Sole-Violán, J, Zaragoza, R, Papiol, E, Suberviola, B, Vallverdú, M, Jimenez-Herrera, M, Albaya-Moreno, A, Berlanga, AC, Ortiz, MD, Ballesteros, JC, Amor, LL, Chinesta, SS, de Alba-Aparicio, M, Estella, A, Martín-Loeches, I, Bodi, M. 01/06/2024. Medicina Intensiva. 48. PMID: 38462398. doi: 10.1016/j.medin.2024.02.006

    Impact of Ventilatory Support Modalities and Timing of Intubation on Longitudinal Recovery of Pulmonary Sequelae in Critically Ill COVID-19 Patients: Non-invasive Mechanical Ventilation Also Matters

    Gonzalez, J, Benitez, I, de Batlle, J, Santisteve, S, Aguilà, M, Torres, G, Gort-Paniello, C, Moncusí-Moix, A, Gracia-Lavedan, E, Ceccato, A, Ferrer, R, Motos, A, Riera, J, Fernández, L, Menéndez, R, Lorente, J, Peñuelas, O, García, D, Roca, O, Peñasco, Y, Ricart, P, Delgado, MM, Aguilera, L, Rodríguez, A, Varela, MB, Pérez-García, F, Pozo-Ladera, J, Solé-Violan, J, Adell-Serrano, B, Novo, MA, Barberán, J, Villar, RA, de Gonzalo-Calvo, D, Torres, A, Roche-Campo, F, Barbe, F. 01/05/2024. American Journal Of Respiratory And Critical Care Medicine. 209

    Immunoglobulins in COVID-19 pneumonia: from the acute phase to the recovery phase

    Peraire, J, García-Pardo, G, Chafino, S, Sánchez, A, Botero-Gallego, M, Olona, M, Espineira, S, Reverté, L, Skouridou, V, Peiró, OM, Gómez-Bertomeu, F, Vidal, F, O’ Sullivan, CK, Rull, A. 06/04/2024. European Journal Of Medical Research. 29. PMID: 38581072. doi: 10.1186/s40001-024-01824-5

    Assessing the impact of real-time random safety audits through full propensity score matching on reliable data from the clinical information system

    Bodi, M, Samper, MA, Sirgo, G, Esteban, F, Canadell, L, Berrueta, J, Gómez, J, Rodríguez, A. 01/04/2024. INTERNATIONAL JOURNAL OF MEDICAL INFORMATICS. 184. PMID: 38330523. doi: 10.1016/j.ijmedinf.2024.105352

    Clustering COVID-19 ARDS patients through the first days of ICU admission. An analysis of the CIBERESUCICOVID Cohort

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    Critical appraisal beyond clinical guidelines for intraabdominal candidiasis

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    "Acute kidney injury in critically ill patients with COVID-19: The AKICOV multicenter study in Catalonia"

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    Management of patients with suspected or confirmed antibiotic allergy. Executive summary of guidance from the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC), the Spanish Society of Allergy and Clinical Immunology (SEAIC), the Spanish Society of Hospital Pharmacy (SEFH) and the Spanish Society of Intensive Medicine and Coronary Care Units (SEMICYUC)

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    Assessment of the implementation of safe medication practices in Intensive Medicine Units

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    Evaluation of five immunoassays and one lateral flow immunochromatography for anti-SARS-CoV-2 antibodies detection

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    Secondary use of data extracted from a clinical information system to assess the adherence of tidal volume and its impact on outcomes

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    Antibiotics in development for multiresistant gram-negative bacilli

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    Trends in mortality in septic patients according to the different organ failure during 15 years

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    Cross-cultural adaptation of the SCORE survey and evaluation of the impact of Real-Time Random Safety Audits in organizational culture: A multicenter study

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    Negative predictive value of procalcitonin to rule out bacterial respiratory co-infection in critical covid-19 patients

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    National Survey: How Do We Approach the Patient at Risk of Clinical Deterioration outside the ICU in the Spanish Context?

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    Current Positioning against Severe Infections Due to Klebsiella pneumoniae in Hospitalized Adults

    Vidal-Cortés, P, Martin-Loeches, I, Rodríguez, A, Bou, G, Cantón, R, Diaz, E, De la Fuente, C, Torre-Cisneros, J, Nuvials, FX, Salavert, M, Aguilar, G, Nieto, M, Ramírez, P, Borges, M, Soriano, C, Ferrer, R, Maseda, E, Zaragoza, R. 01/09/2022. Antibiotics-Basel. 11. PMID: 36139940. doi: 10.3390/antibiotics11091160

    Prior influenza vaccine is not a risk factor for bacterial coinfection in patients admitted to the ICU due to severe influenza

    Proaños, NJ, Reyes, LF, Bastidas, A, Martin-Loeches, I, Díaz, E, Suberviola, B, Moreno, G, Bodí, M, Nieto, M, Estella, A, Sole-Violán, J, Curcio, D, Papiol, E, Guardiola, J, Rodríguez, A, Group, GSW. 01/08/2022. Medicina Intensiva. 46. PMID: 34175139. doi: 10.1016/j.medin.2021.05.013

    Lipoprotein Profile in Immunological Non-Responders PLHIV after Antiretroviral Therapy Initiation

    Masip, J, Jorba, R, López-Dupla, M, Domingo, P, Pacheco, YM, García-Pardo, G, Martínez, E, Viladés, C, Veloso, S, Alba, V, Olona, M, Vidal, F, Gómez-Bertomeu, F, Peraire, J, Rull, A. 01/08/2022. International Journal Of Molecular Sciences. 23. PMID: 35897644. doi: 10.3390/ijms23158071

    Impact of one year of pandemic on Spanish Intensive Care Units

    Vidal-Cortés, P, Martín, MC, Díaz, E, Bodí, M, Igeño, JC, Garnacho-Montero, J. 01/08/2022. Revista Espanola De Quimioterapia. 35. PMID: 35678324. doi: 10.37201/req/025.2022

    Impact of Aspergillus spp. isolation in the first 24 hours of admission in critically ill patients with severe influenza virus pneumonia

    Claverias, L, Daniel, X, Martin-Loeches, I, Vidal-Cortez, P, Gómez-Bertomeu, F, Trefler, S, Zaragoza, R, Borges-Sa, M, Reyes, LF, Quindós, G, Peman, J, Bodí, M, Díaz, E, Sarvisé, C, Pico, E, Papiol, E, Solé-Violan, J, Marín-Corral, J, Guardiola, JJ, Rodríguez, A. 01/08/2022. Medicina Intensiva. 46. doi: 10.1016/j.medin.2021.12.005

    Impact of Aspergillus spp. isolation in the first 24 hours of admission in critically ill patients with severe influenza virus pneumonia.

    Claverias L, Daniel X, Martín-Loeches I, Vidal-Cortez P, Gómez-Bertomeu F, Trefler S, Zaragoza R, Borges-Sa M, Reyes LF, Quindós G, Peman J, Bodí M, Díaz E, Sarvisé C, Pico E, Papiol E, Solé-Violan J, Marín-Corral J, Guardiola JJ, Rodríguez A. 01/08/2022. Medicina Intensiva. 46. PMID: 35868719. doi: 10.1016/j.medine.2021.12.013

    Prior influenza vaccine is not a risk factor for bacterial coinfection in patients admitted to the ICU due to severe influenza.

    Proaños NJ, Reyes LF, Bastidas A, Martín-Loeches I, Díaz E, Suberviola B, Moreno G, Bodí M, Nieto M, Estella A, Sole-Violán J, Curcio D, Papiol E, Guardiola J, Rodríguez A. 01/08/2022. Medicina Intensiva. 46. PMID: 35868720. doi: 10.1016/j.medine.2021.05.009

    Prognostic implications of comorbidity patterns in critically ill COVID-19 patients: A multicenter, observational study

    Benítez, ID, de Batlle, J, Torres, G, González, J, De Gonzalo-Calvo, D, Targa, ADS, Gort-Paniello, C, Moncusí-Moix, A, Ceccato, A, Fernández-Barat, L, Ferrer, R, Garcia-Gasulla, D, Menéndez, R, Motos, A, Peñuelas, O, Riera, J, Bermejo-Martin, JF, Peñasco, Y, Ricart, P, Delgado, MCM, Aguilera, L, Rodríguez, A, Varela, MVB, Suarez-Sipmann, F, Pozo-Laderas, JC, Solé-Violan, J, Nieto, M, Novo, MA, Barberán, J, Villar, RA, Garnacho-Montero, J, García-Garmendia, JL, Gómez, JM, Lorente, JA, Ortiz, AB, Lomas, LT, López-Ramos, E, Ubeda, A, Catalán-González, M, Sánchez-Miralles, A, Varela, IM, García, RNJ, Franco, N, Gumucio-Sanguino, VD, Garcia, AH, Bustamante-Munguira, E, Valdivia, LJ, Caballero, J, Gallego, E, de la Gándara, AM, Castellanos-Ortega, A, Trenado, J, Marin-Corral, J, Albaiceta, GM, de la Torre, MD, Loza-Vázquez, A, Vidal, P, Messa, JL, Añón, JM, Pérez, CC, Sagredo, V, Bofill, N, Carbonell, N, Socias, L, Barberà, C, Estella, A, Mendez, MV, Diaz, E, Lago, AL, Torres, A, Barbé, F. 01/07/2022. Lancet Regional Health-Europe. 18. PMID: 35655660. doi: 10.1016/j.lanepe.2022.100422

    Ventilator-associated pneumonia in critically ill patients with COVID-19 infection: a narrative review

    Boyd, S, Nseir, S, Rodriguez, A, Martin-Loeches, I. 01/06/2022. Erj Open Research. 8. PMID: 35891621. doi: 10.1183/23120541.00046-2022

    Dexamethasone as risk-factor for ICU-acquired respiratory tract infections in severe COVID-19

    Reyes, LF, Rodriguez, A, Bastidas, A, Parra-Tanoux, D, Fuentes, YV, García-Gallo, E, Moreno, G, Ospina-Tascon, G, Hernandez, G, Silva, E, Díaz, AM, Jibaja, M, Vera-Alarcon, M, Díaz, E, Bodí, M, Solé-Violán, J, Ferrer, R, Albaya-Moreno, A, Socias, L, Estella, A, Loza-Vazquez, A, Jorge-García, R, Sancho, I, Martin-Loeches, I. 01/06/2022. Journal Of Critical Care. 69. PMID: 35217370. doi: 10.1016/j.jcrc.2022.154014

    Disease-specific gaps within fungal respiratory tract infections: clinical features, diagnosis, and management in critically ill patients

    Martin-Loeches, I, Nseir, S, Rodriguez, A, Azoulay, E. 01/05/2022. Current Opinion In Pulmonary Medicine. 28. PMID: 35152230. doi: 10.1097/MCP.0000000000000865

    Elevated a-Ketoglutaric Acid Concentrations and a Lipid-Balanced Signature Are the Key Factors in Long-Term HIV Control.

    Masip J, Rallón N, Yeregui E, Olona M, Resino S, Benito JM, Viladés C, García-Pardo G, Alcamí J, Ruiz-Mateos E, Gómez-Bertomeu F, Vargas M, Navarro M, Oteo JA, Pineda JA, Martí A, Alba V, Vidal F, Peraire J, Rull A. 20/04/2022. Frontiers in immunology. 13. PMID: 35514981. doi: 10.3389/fimmu.2022.822272

    A novel model to predict severe COVID-19 and mortality using an artificial intelligence algorithm to interpret chest radiographs and clinical variables

    Munera, N, Garcia-Gallo, E, Gonzalez, A, Zea, J, Fuentes, YV, Serrano, C, Ruiz-Cuartas, A, Rodriguez, A, Reyes, LF. 01/04/2022. Erj Open Research. 8. PMID: 35765299. doi: 10.1183/23120541.00010-2022

    Susceptibility and risk of SARS-COV-2 infection among middle-aged and older adults in Tarragona area, Spain

    Satué-Gracia, EM, Vila-Cóorcoles, A, De Diego-Cabanes, C, Vila-Rovira, A, Torrente-Fraga, C, Gómez-Bertomeu, F, Hospital-Guardiola, I, Ochoa-Gondar, O, Martín-Luján, F. 18/03/2022. Medicina Clinica. 158. PMID: 34074472. doi: 10.1016/j.medcli.2021.03.027

    Resistin and IL-15 as Predictors of Invasive Mechanical Ventilation in COVID-19 Pneumonia Irrespective of the Presence of Obesity and Metabolic Syndrome

    Perpiñan, C, Bertran, L, Terra, X, Aguilar, C, Binetti, J, Lopez-Dupla, M, Rull, A, Reverté, L, Yeregui, E, Gómez-Bertomeu, F, Peraire, J, Auguet, T. 01/03/2022. Journal of personalized medicine. 12. PMID: 35330391. doi: 10.3390/jpm12030391

    Non-invasive oxygenation support in acutely hypoxemic COVID-19 patients admitted to the ICU: a multicenter observational retrospective study

    Wendel-Garcia, PD, Mas, A, González-Isern, C, Ferrer, R, Máñez, R, Masclans, JR, Sandoval, E, Vera, P, Trenado, J, Fernández, R, Sirvent, JM, Martínez, M, Ibarz, M, Garro, P, Lopera, JL, Bodí, M, Yébenes-Reyes, JC, Triginer, C, Vallverdú, I, Baró, A, Bodí, F, Saludes, P, Valencia, M, Roche-Campo, F, Huerta, A, Cambra, FJ, Barberà, C, Echevarria, J, Peñuelas, O, Mancebo, J. 08/02/2022. Critical Care. 26. PMID: 35135588. doi: 10.1186/s13054-022-03905-5

    Adipokines as New Biomarkers of Immune Recovery: Apelin Receptor, RBP4 and ZAG Are Related to CD4+ T-Cell Reconstitution in PLHIV on Suppressive Antiretroviral Therapy

    Yeregui, E, Masip, J, Viladés, C, Domingo, P, Pacheco, YM, Blanco, J, Mallolas, J, Alba, V, Vargas, M, García-Pardo, G, Negredo, E, Olona, M, Vidal-Gonzalez, J, Peraire, M, Martí, A, Reverté, L, Gómez-Bertomeu, F, Leal, M, Vidal, F, Peraire, J, Rull, A. 01/02/2022. International Journal Of Molecular Sciences. 23. PMID: 35216318. doi: 10.3390/ijms23042202

    Detection of frailty and palliative needs from discharged critical care patients in collaboration with primary care

    Ferré, C, Canelles, S, Daniel, X, Rubio, O, Esteban, F, Pobo, A. 01/02/2022. Medicina Intensiva. 46. PMID: 33531189. doi: 10.1016/j.medin.2020.11.007

    Recommendations for the management of critically ill patients with COVID-19 in Intensive Care Units

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    Early Tracheostomy for Managing ICU Capacity During the COVID-19 Outbreak A Propensity-Matched Cohort Study

    Hernandez, G, Ramos, FJ, Anon, JM, Ortiz, R, Colinas, L, Masclans, JR, De Haro, C, Ortega, A, Penuelas, O, Cruz-Delgado, MD, Canabal, A, Plans, O, Vaquero, C, Rialp, G, Gordo, F, Lesmes, A, Martinez, M, Figueira, JC, Gomez-Carranza, A, Corrales, R, Castellvi, A, Castineiras, B, Frutos-Vivar, F, Prada, J, De Pablo, R, Naharro, A, Montejo, JC, Diaz, C, Santos-Peral, A, Padilla, R, Marin-Corral, J, Rodriguez-Solis, C, Sanchez-Giralt, JA, Jimenez, J, Cuena, R, Perez-Hoyos, S, Roca, O. 01/01/2022. Chest. 161. PMID: 34147502. doi: 10.1016/j.chest.2021.06.015

    Fetuin-A, inter-a-trypsin inhibitor, glutamic acid and ChoE (18:0) are key biomarkers in a panel distinguishing mild from critical coronavirus disease 2019 outcomes

    Reverté, L, Yeregui, E, Olona, M, Gutiérrez-Valencia, A, Buzón, MJ, Martí, A, Gómez-Bertomeu, F, Auguet, T, López-Cortés, LF, Burgos, J, Benavent-Bofill, C, Boqué, C, García-Pardo, G, Ruiz-Mateos, E, Mestre, MT, Vidal, F, Viladés, C, Peraire, J, Rull, A. 01/01/2022. Clinical And Translational Medicine. 12. PMID: 35075803. doi: 10.1002/ctm2.704

    Fungal Planet description sheets: 1436-1477.

    Tan YP, Bishop-Hurley SL, Shivas RG, Cowan DA, Maggs-Kölling G, Maharachchikumbura SSN, Pinruan U, Bransgrove KL, De la Peña-Lastra S, Larsson E, Lebel T, Mahadevakumar S, Mateos A, Osieck ER, Rigueiro-Rodríguez A, Sommai S, Ajithkumar K, Akulov A, Anderson FE, Arenas F, Balashov S, Bañares Á, Berger DK, Bianchinotti MV, Bien S, Bilanski P, Boxshall AG, Bradshaw M, Broadbridge J, Calaça FJS, Campos-Quiroz C, Carrasco-Fernández J, Castro JF, Chaimongkol S, Chandranayaka S, Chen Y, Comben D, Dearnaley JDW, Ferreira-Sá AS, Dhileepan K, Díaz ML, Divakar PK, Xavier-Santos S, Fernández-Bravo A, Gené J, Guard FE, Guerra M, Gunaseelan S, Houbraken J, Janik-Superson K, Jankowiak R, Jeppson M, Jurjevic Ž, Kaliyaperumal M, Kelly LA, Kezo K, Khalid AN, Khamsuntorn P, Kidanemariam D, Kiran M, Lacey E, Langer GJ, López-Llorca LV, Luangsa-Ard JJ, Lueangjaroenkit P, Lumbsch HT, Maciá-Vicente JG, Mamatha Bhanu LS, Marney TS, Marqués-Gálvez JE, Morte A, Naseer A, Navarro-Ródenas A, Oyedele O, Peters S, Piskorski S, Quijada L, Ramírez GH, Raja K, Razzaq A, Rico VJ, Rodríguez A, Ruszkiewicz-Michalska M, Sánchez RM, Santelices C, Savitha AS, Serrano M, Leonardo-Silva L, Solheim H, Somrithipol S, Sreenivasa MY, Stepniewska H, Strapagiel D, Taylor T, Torres-Garcia D, Vauras J, Villarreal M, Visagie CM, Wolkowycki M, Yingkunchao W, Zapora E, Groenewald JZ, Crous PW. 20/12/2022. Persoonia. 49. PMID: 38234383. doi: 10.3767/persoonia.2022.49.08

    Endothelial Damage and the Microcirculation in Critical Illness

    Cusack, R, Leone, M, Rodriguez, AH, Martin-Loeches, I. 01/12/2022. Biomedicines. 10. PMID: 36551905. doi: 10.3390/biomedicines10123150

    Cross-cultural adaptation of the SCORE survey and evaluation of the impact of Real-Time Random Safety Audits in organizational culture: A multicenter study.

    Sirgo G, Olona M, Martín-Delgado MC, Gordo F, Trenado J, García M, Bodí M. 01/10/2022. Medicina Intensiva. 46. PMID: 36155679. doi: 10.1016/j.medine.2021.03.005

    Impact of difficult sedation on the management and outcome of critically ill patients

    Castillejos, DG, Rubio, ML, Ferre, C, de Gracia, MD, Bodí, M, Sandiumenge, A. 01/07/2022. Nursing In Critical Care. 27. PMID: 32975003. doi: 10.1111/nicc.12558

    Detection of frailty and palliative needs from discharged critical care patients in collaboration with primary care.

    Ferré C, Canelles S, Daniel X, Rubio O, Esteban F, Pobo A. 01/02/2022. Medicina Intensiva. 46. PMID: 34863667. doi: 10.1016/j.medine.2021.11.018

    Higher frequency of comorbidities in fully vaccinated patients admitted to the ICU due to severe COVID-19: a prospective, multicentre, observational study

    Motos, A, López-Gavín, A, Riera, J, Ceccato, A, Fernández-Barat, L, Bermejo-Martin, JF, Ferrer, R, de Gonzalo-Calvo, D, Menéndez, R, Pérez-Arnal, R, García-Gasulla, D, Rodriguez, A, Peñuelas, O, Lorente, JA, Almansa, R, Gabarrus, A, Marin-Corral, J, Ricart, P, Roche-Campo, F, Chinesta, SS, Socias, L, Barbé, F, Torres, A. 01/02/2022. European Respiratory Journal. 59. PMID: 34824059. doi: 10.1183/13993003.02275-2021

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