Presentació dels Hospitals
Col·labora

Grup d’Estudi en Malalties Metabòliques Associades a la Insulin-Resistència (GEMMAIR)

MALALTIES METABÒLIQUES I NUTRICIÓ
OBESITAT PATOGÈNIA BIOMARCADORS DIANES TERAPÈUTIQUES MALALTIA DEL FETGE GRAS NO ALCOHÒLIC
OBJECTIUS

GEMMAIR té una llarga trajectòria en l’estudi de la fisiopatologia de l’obesitat i les malalties associades. Actualment, el grup centra principalment la seva recerca en l’estudi de l’hepatopatia grassa no alcohòlica i les seves comorbiditats, com són l’obesitat, la diabetis mellitus de tipus 2 i la síndrome metabòlica, amb la finalitat de definir nous mecanismes moleculars implicats en la malaltia, i trobar possibles biomarcadors i potencials dianes terapèutiques.

RESPONSABLES

  • Dra. Teresa Auguet Quintillà

  • PRESENTACIÓ
  • Línies de recerca
  • MEMBRES DEL GRUP
  • Membres del grup
  • PROJECTES
  • TRANSFERÈNCIA
  • CONTACTE
  • Publicacions
  • Difusió

El Grup d’Estudi en Malalties Metabòliques Associades a la Insulin-Resistència (GEMMAIR) és un grup de recerca clínica i bàsica format per un equip multidisciplinari. Aquest es compon de personal investigador mèdic i experimental que pertany a l’Hospital Universitari de Tarragona Joan XXIII i a l’Hospital Universitari Sant Joan de Reus: metges internistes, cirurgians, patòlegs, biòlegs moleculars i tècnics de laboratori.

GEMMAIR té una trajectòria de més de 25 anys d’experiència en l’estudi de malalties hepàtiques cròniques i de més de 15 anys en l’estudi de l’obesitat i les malalties associades. Tanmateix, GEMMAIR està acreditat com a grup consolidat per l’Agència de Gestió d’Ajuts Universitaris i de Recerca (AGAUR) des de l’any 2009 i és un grup de recerca reconegut per la Universitat Rovira i Virgili (URV).

GEMMAIR ha realitzar diverses col·laboracions en l’àmbit nacional i internacional; a més el grup té una gran vinculació amb l’àmbit acadèmic, donat que la major part dels membres del grup son professors de la URV. També s’hi han dut a terme un gran nombre de tesis doctorals i treballs de final de grau i de màster, pel que GEMMAIR, té experiència en la formació del personal investigador novell.

  • Estudi de citoquines i adipocitoquines en la fisiopatologia de l’obesitat, la síndrome metabòlica i la malaltia de fetge gras no alcohòlic (MFGNA).
  • Expressió gènica, factors transcripcionals i epigenètica en la MFGNA.
  • Estudi dels metabòlits derivats de la microbiota en la MFGNA.
  • Ciències òmiques (metabolòmica, miRNòmica i proteòmica) en el diagnòstic no invasiu de l’esteatohepatitis no alcohòlica.
  • Ciències òmiques (metabolòmica i proteòmica) en l’estudi de la placa arterial arterioscleròtica.
  • Biomarcadors pronòstics de la COVID-19 en pacients amb obesitat i/o síndrome metabòlica.
  • Malaltia tromboembòlica venosa.

  • An open, multicentre, prospective, non-interventional study of the CE-marked medical device GlucoTab, according to intended use without additional invasive and stressful measures with a matched retrospective control group. Project Grant Agreement EIT Health. IP: Maria Teresa Auguet Quintillà. 2024-2025

  • Consumption of grapes with different (poly)phenol content in the adaptation to photoperiod. PROYECTOS DE GENERACIÓN DE CONOCIMIENTO 2023 PLAN ESTATAL. IP: Begoña Muguerza i Anna Arola Arnal. 2023-2027

  • Microplastics: Dietary intake, impact on gut and promotion on liver damage (MP-DiGuLi). PROYECTOS DE GENERACIÓN DE CONOCIMIENTO 2022 PLAN ESTATAL. IP: Martí Nadal i Joaquim Rovira. IISPV. 2024-2027. 252.250,00€

  • WASTEwater as a source of knowledge on SARS-CoV-2 and other potentially pandemic VIRuses: a One Health approach (VIRWASTE). AGAUR. 01/05/2021-31/12/2023. 316.000€.

  • Biomarcadores de pronóstico circulantes y celulares para la progresión de COVID19 enpacientes con infección por SARS-CoV-2 utilizando ciencia multiómica. AGAUR. FRANCISCO VIDAL MARSAL. (FUNDACIÓ PRIVADA IISPV). 30/03/2020-31/12/2020.
    201.070,79 €.

  • PI16/00498, Papel de la disbiosis intestinal en la patogenia de la enfermedad del hígado graso no alcohólico a través de la regulación de la homeostasis lipídica hepática. Instituto de Salud Carlos III. Maria Teresa Auguet Quintillà. URV. 01/01/2017-31/12/2019. 71.500€.

  • 2016PFR-URV-B2-72, Grup d’Estudi de Malalties Metabòliques associades a Insulin
    Resistència (GEMMAIR) Universitat Rovira i Virgili. Cristobal Manuel Richart Jurado.
    URV. 01/01/2017-30/06/2018. 6.572,17 €.

  • 2016PFR-URV-B2-72, Programa de suport als grups de recerca reconeguts. Grup d’Estudi
    de Malalties Metabòliques associades a Insulin Resistència (GEMMAIR) Universitat
    Rovira i Virgili. Cristobal Manuel Richart Jurado. URV. 01/01/2017- 31/12/2017.
    6.572,17 €.

  • 2015PFR-URV-B2-72, Grup d’Estudi de Malalties Metabòliques associades a Insulin
    Resistència (GEMMAIR) Universitat Rovira i Virgili. Cristobal Manuel Richart Jurado.URV.
    01/01/2015-31/12/2017. 6.839 €.

  • 2015PFR-URV-B2-72, Programa de suport als grups de recerca reconeguts. Grup d’Estudi
    de Malalties Metabòliques associades a Insulin Resistència (GEMMAIR) Universitat
    Rovira i Virgili. Cristobal Manuel Richart Jurado.URV. 01/01/2015- 31/12/2017. 6.839 €.

    Assajos clínics:

  • A Phase IIb/III Randomized, Double-blind,Placebo-controlled Study to Evaluate the Safety and Efficacy of Cotadutide in Participants with Non-cirrhotic Non-Alcoholic
    Steatohepatitis with Fibrosis (D5671C00006). AstraZenecaAB. Desde 2022. IP: Dr. David Riesco

  • Phase 2 randomized, double-blind, placebo-controlled, proof-of-concept study to evaluate the efficacy and safety of recombinant human plasma gelsolin (RHUPGSN) added to standard of care for treatment of subjects with severe covid-19 pneumonia.
    Desde 2020. IP: Dra. T. Auguet

  • Safety and efficacy of favipipravir in COVID-19 patients with pneumonia. A randomized, double blind, placebo controlled study (FAVID01-20-SP). Ferrer Internacional, S.A. Desde 2020. IP: Dra. T. Auguet

    Año

    Effects of Animal-Based Foods on Metabolic Outcomes in Adults with MASLD and Comorbidities: A Systematic Review of Randomized Controlled Trials (2020-2026).

    Jurek JM, Zablocka-Slowinska K, Pieczynska J, Lipert A, Clavero-Mestres H, Auguet T. 08/05/2026. Nutrients. 18. PMID: 42196968. doi: 10.3390/nu18101508

    Platelet-Activating Factor Pathway in Women With Metabolic Dysfunction-Associated Steatotic Liver Disease and Obesity.

    Duran-Bertran J, Clavero-Mestres H, Mahmoudian R, Muñiz-Piera S, Aguilar C, Riesco D, Camaron J, Martínez S, Vives M, París M, Sabench F, Auguet T. 01/05/2026. Obesity. 34. PMID: 41885053. doi: 10.1002/oby.70178

    Impact of bariatric surgery on the gut microbiota and metabolomic profile of the enterohepatic axis in an experimental model of obesity.

    Homs E, Vives M, Torrell H, Castillo DD, Sánchez A, Sabench F. 01/04/2026. Cirugia Espanola. 104. PMID: 41654113. doi: 10.1016/j.cireng.2026.800297

    Significant Activity of Pytren-2Q, a 2-Quinoline Polyamine Compound, against High-Concern Human Pathogenic Fungi.

    Inclán M, Clares MP, Álvarez-Duarte E, Fernández-Silva F, Salas V, Guarro J, Chicote JU, Verdejo B, Delgado-Pinar E, García-España E, García-España A, Calvo E. 17/02/2026. ACS Omega. 11. PMID: 41726695. doi: 10.1021/acsomega.5c09700

    Exploring the Role of TAS2Rs in Obesity: Insights From Human and Rat Models

    Descamps-Solà, M, Jalsevac, F, Vilalta, A, Fontcuberta, M, Park, H, Aguilar, C, Auguet, T, Beltrán-Debón, R, Rodríguez-Gallego, E, Pinent, M, Terra, X, Ardévol, A. 01/01/2026. Obesity. 34. PMID: 41140001. doi: 10.1002/oby.70055

    sTREM2 evaluation in women with metabolic dysfunction-associated steatotic liver disease: Advancing diagnostic approaches for early MASH

    Mahmoudian, R, Clavero-Mestres, H, Rusu, EC, Arredondo-Prats, V, Aguilar, C, Chicote, JU, Martinez, S, Riesco, D, Bartra, E, Borras, AT, Sabench, F, Auguet, T. 01/11/2025. European Journal Of Internal Medicine. 141. PMID: 40716976. doi: 10.1016/j.ejim.2025.07.014

    A Combination of Lacticaseibacillus paracasei CECT 30660 and Bifidobacterium longum subsp. infantis CECT 7210 Cell-Free Supernatants Reduces LPS-Induced Preterm Birth and Systemic Inflammation in Pregnant Mice

    Quesada-Vázquez, S, García, MCD, Cifuentes-Orjuela, G, Antolín, A, Alcaide-Hidalgo, JM, Jiménez, J, Puiggròs, F, Caimari, A, Sabench, F, Del Bas, JM, Escoté, X, Moreno-Muñoz, JA. 31/10/2025. Nutrients. 17. PMID: 41228502. doi: 10.3390/nu17213429

    Systematic Review of the Effects of Plant-Based Foods on Metabolic Outcomes in Adults with MASLD and Comorbidities Such as Obesity, Metabolic Syndrome, and Type 2 Diabetes

    Jurek, JM, Zablocka-Slowinska, K, Pieczynska, J, Mestres, HC, Auguet, T. 22/09/2025. Nutrients. 17. PMID: 41010543. doi: 10.3390/nu17183020

    Development and Validation of the Psychometric Properties of the FitMIND Foundation Sweets Addiction Scale-A Pilot Study

    Choroszynski, M, Jurek, JM, Mizia, S, Hudaszek, K, Clavero-Mestres, H, Auguet, T, Siennicka, A. 12/06/2025. Nutrients. 17. PMID: 40573095. doi: 10.3390/nu17121985

    Differential Expression of Lipid Metabolism Genes, CROT and ABCG1, in Obese Patients with Comorbid Depressive Disorder and Risk of MASLD

    Jurek, JM, Rusu, EC, Camaron, J, Clavero-Mestres, H, Aguilar, C, Riesco, D, Xifré, B, Chicote, JU, Martinez, S, Vives, M, Sabench, F, Auguet, T. 11/06/2025. Metabolites. 15. PMID: 40559416. doi: 10.3390/metabo15060392

    C-reactive protein as a predictor of complicated acute cholecystitis: A cohort study.

    Renau G, Abelló D, Sabench F, Doménech J, Sánchez A. 09/06/2025. Revista De Gastroenterologia De Mexico (english). 90. PMID: 40494691. doi: 10.1016/j.rgmxen.2025.02.004

    Uncovering hepatic transcriptomic and circulating proteomic signatures in MASH: A meta-analysis and machine learning-based biomarker discovery.

    Rusu EC, Clavero-Mestres H, Sánchez-Álvarez M, Veciana-Molins M, Bertran L, Monfort-Lanzas P, Aguilar C, Camaron J, Auguet T. 01/06/2025. Computers In Biology And Medicine. 191. PMID: 40220593. doi: 10.1016/j.compbiomed.2025.110170

    Clinical presentation and prognosis of acute symptomatic pulmonary embolism in patients with concomitant upper-extremity versus lower-extremity deep vein thrombosis.

    Dubois-Silva Á, Bikdeli B, Jiménez D, Barbagelata-López C, Fernández-Capitán C, Skride A, Pham KQ, Porras JA, Pacheco-Gómez N, Monreal M. 20/05/2025. Thorax. 80. PMID: 40081905. doi: 10.1136/thorax-2024-221960

    Differential Profiles of Gut Microbiota-Derived Metabolites of Bile Acids and Propionate as Potential Predictors of Depressive Disorder in Women with Morbid Obesity at High Risk of Metabolic Dysfunction-Associated Steatotic Liver Disease-A Pilot Study

    Jurek, JM, Xifré, B, Rusu, EC, Clavero-Mestres, H, Mahmoudian, R, Aguilar, C, Riesco, D, Chicote, JU, Martinez, S, Vives, M, Sabench, F, Auguet, T. 12/05/2025. CURRENT ISSUES IN MOLECULAR BIOLOGY. 47. PMID: 40699752. doi: 10.3390/cimb47050353

    C-reactive protein as a predictor of complicated acute cholecystitis: A cohort study

    Renau, G, Abelló, D, Sabench, F, Doménech, J, Sánchez, A. 01/05/2025. Revista de gastroenterologia de Mexico. 90. doi: 10.1016/j.rgmx.2025.02.002

    The Impact of Dietary Interventions on Metabolic Outcomes in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) and Comorbid Conditions, Including Obesity and Type 2 Diabetes

    Jurek, JM, Zablocka-Sowinska, K, Mestres, HC, Gutiérrez, LR, Camaron, J, Auguet, T. 03/04/2025. Nutrients. 17. PMID: 40219014. doi: 10.3390/nu17071257

    Exploring the role of fatty acid esters of hydroxy fatty acids in metabolic dysfunction-associated steatotic liver disease in morbidly obese women.

    Bertran L, Rusu EC, Aguilar C, Auguet T, Richart C. 01/02/2025. Digestive And Liver Disease. 57. PMID: 39532579. doi: 10.1016/j.dld.2024.09.026

    Circulating proteomic profiles in women with morbid obesity compared to normal-weight women

    Bertran, L, Rusu, EC, Guirro, M, Aguilar, C, Auguet, T, Richart, C. 06/01/2025. Journal Of Proteomics. 310. PMID: 39307454. doi: 10.1016/j.jprot.2024.105317

    Multi-omics profiling reveals altered mitochondrial metabolism in adipose tissue from patients with metabolic dysfunction-associated steatohepatitis

    Castañé, H, Jiménez-Franco, A, Hernández-Aguilera, A, Martínez-Navidad, C, Cambra-Cortés, V, Onoiu, AI, Jiménez-Aguilar, JM, Paris, M, Hernández, M, Parada, D, Guilarte, C, Zorzano, A, Hernández-Alvarez, MI, Camps, J, Joven, J. 01/01/2025. EBioMedicine. 111. PMID: 39731853. doi: 10.1016/j.ebiom.2024.105532

    Results of the national registry of patients diagnosed with inflammatory bowel disease candidates for bariatric surgery (ReNacEIBar).

    Ferrer-Márquez M, Frutos Bernal MD, Ruiz de Gordejuela AG, García-Redondo M, Millán M, Sabench Pereferrer F, Tarascó Palomares J. 01/01/2024. Cirugia Espanola. 102. PMID: 37952719. doi: 10.1016/j.cireng.2023.05.018

    Metabolic adaptations in severe obesity: Insights from circulating oxylipins before and after weight loss

    Jiménez-Franco, A, Castañé, H, Martínez-Navidad, C, Placed-Gallego, C, Hernández-Aguilera, A, Fernández-Arroyo, S, Samarra, I, Canela-Capdevila, M, Arenas, M, Zorzano, A, Hernández-Alvarez, MI, Del Castillo, D, Paris, M, Menendez, JA, Camps, J, Joven, J. 01/01/2024. Clinical Nutrition. 43. PMID: 38101315. doi: 10.1016/j.clnu.2023.12.002

    Metabolic-Associated Fatty Liver Disease and Weight Loss After Bariatric Surgery: A Systematic Review and Meta-Analysis

    Sabench, F, Rusu, EC, Clavero-Mestres, H, Arredondo-Prats, V, Veciana-Molins, M, Muñiz-Piera, S, Vives, M, Aguilar, C, Bartra, E, París-Sans, M, Alibalic, A, Quintillà, MTA. 01/12/2024. Obesity Surgery. 34. PMID: 39560894. doi: 10.1007/s11695-024-07585-8

    An Effective Liposome-Based Nanodelivery System for Naphthalene Derivative Polyamines with Antitumor Activity

    Pont, I, Felipe, R, Frias, JC, Chicote, JU, Garcia-Espana, A, Garcia-Espana, E, Albelda, MT. 01/11/2024. Biomolecules. 14. PMID: 39595524. doi: 10.3390/biom14111347

    Metabolic profiling of tryptophan pathways: Implications for obesity and metabolic dysfunction-associated steatotic liver disease

    Arto, C, Rusu, EC, Clavero-Mestres, H, Barrientos-Riosalido, A, Bertran, L, Mahmoudian, R, Aguilar, C, Riesco, D, Chicote, JU, Parada, D, Martinez, S, Sabench, F, Richart, C, Auguet, T. 01/11/2024. European Journal Of Clinical Investigation. 54. PMID: 38940215. doi: 10.1111/eci.14279

    Profiling bitter taste receptors (TAS2R) along the gastrointestinal tract and their influence on enterohormone secretion. Gender- and age-related effects in the colon

    Jalsevac, F, Descamps-Solà, M, Grau-Bové, C, Segú, H, Auguet, T, Avilés-Jurado, FX, Balaguer, F, Jorba, R, Beltrán-Debón, R, Blay, MT, Barbadora, XT, Pinent, M, Ardévol, A. 17/10/2024. Frontiers in endocrinology. 15. PMID: 39512758. doi: 10.3389/fendo.2024.1436580

    Towards understanding post-COVID-19 condition: A systematic meta-analysis of transcriptomic alterations with sex-specific insights.

    Rusu EC, Monfort-Lanzas P, Bertran L, Barrientos-Riosalido A, Solé E, Mahmoudian R, Aguilar C, Briansó S, Mohamed F, Garcia S, Camaron J, Auguet T. 01/06/2024. Computers In Biology And Medicine. 175. PMID: 38657468. doi: 10.1016/j.compbiomed.2024.108507

    Untargeted lipidomics analysis in women with morbid obesity and type 2 diabetes mellitus: A comprehensive study

    Bertran, L, Capellades, J, Abello, S, Aguilar, C, Auguet, T, Richart, C. 14/05/2024. Plos One. 19. PMID: 38743756. doi: 10.1371/journal.pone.0303569

    A prospective, randomized, blinded study on the efficacy of using corticosteroids in hydrodilatation as a treatment for adhesive capsulitis of the shoulder

    Gebellí-Jové, JT, Buñuel-Viñau, A, Canela-Capdevila, M, Camps, J, Sabench, F, Iftimie-Iftimie, P. 20/03/2024. Shoulder & Elbow. 17. PMID: 39552668. doi: 10.1177/17585732241239030

    Platelet-associated biomarkers in nonalcoholic steatohepatitis: Insights from a female cohort with obesity

    Duran-Bertran, J, Rusu, EC, Barrientos-Riosalido, A, Bertran, L, Mahmoudian, R, Aguilar, C, Riesco, D, Martínez, S, Chicote, JU, Sabench, F, Richart, C, Auguet, T. 01/03/2024. European Journal Of Clinical Investigation. 54. PMID: 37929908. doi: 10.1111/eci.14123

    Safety and efficacy of favipiravir in COVID-19 patients with pneumonia. A randomized, double-blind, placebo-controlled study (FAVID).

    Horcajada JP, Aldonza R, Real M, Castañeda-Espinosa S, Sendra E, Gomez-Junyent J, López-Montesinos I, Gómez-Zorrilla S, Briansó S, Duran-Taberna M, Fernández A, Tarragó C, Auguet-Quintillá T. 25/02/2024. PNEUMONIA. 16. PMID: 38402214. doi: 10.1186/s41479-023-00124-6

    Clinical and Biomarker Profile Responses to Rehabilitation Treatment in Patients with Long COVID Characterized by Chronic Fatigue

    Binetti, J, Real, M, Renzulli, M, Bertran, L, Riesco, D, Perpiñan, C, Mohedano, A, Segundo, RS, Ortiz, M, Porras, JA, Pineda, DR, Auguet, T. 01/07/2023. Viruses-Basel. 15. PMID: 37515140. doi: 10.3390/v15071452

    LC/MS-Based Untargeted Metabolomics Study in Women with Nonalcoholic Steatohepatitis Associated with Morbid Obesity

    Bertran, L, Capellades, J, Abelló, S, Durán-Bertran, J, Aguilar, C, Martinez, S, Sabench, F, Correig, X, Yanes, O, Auguet, T, Richart, C. 01/06/2023. International Journal Of Molecular Sciences. 24. PMID: 37372937. doi: 10.3390/ijms24129789

    LC/MS-Based Untargeted Metabolomics Analysis in Women with Morbid Obesity and Associated Type 2 Diabetes Mellitus

    Auguet, T, Bertran, L, Capellades, J, Abelló, S, Aguilar, C, Sabench, F, Del Castillo, D, Correig, X, Yanes, O, Richart, C. 24/04/2023. International Journal Of Molecular Sciences. 24. PMID: 37175468. doi: 10.3390/ijms24097761

    Expression of STING in Women with Morbid Obesity and Nonalcoholic Fatty Liver Disease

    Bertran, L, Adalid, L, Vilaró-Blay, M, Barrientos-Riosalido, A, Aguilar, C, Martínez, S, Sabench, F, Del Castillo, D, Porras, JA, Alibalic, A, Richart, C, Auguet, T. 01/04/2023. Metabolites. 13. PMID: 37110154. doi: 10.3390/metabo13040496

    The Role of Olfactomedin 2 in the Adipose Tissue-Liver Axis and Its Implication in Obesity-Associated Nonalcoholic Fatty Liver Disease

    Barrientos-Riosalido, A, Bertran, L, Vilaró-Blay, M, Aguilar, C, Martínez, S, Paris, M, Sabench, F, Riesco, D, Binetti, J, Del Castillo, D, Richart, C, Auguet, T. 01/03/2023. International Journal Of Molecular Sciences. 24. PMID: 36982296. doi: 10.3390/ijms24065221

    Increased Hepatic ATG7 mRNA and ATG7 Protein Expression in Nonalcoholic Steatohepatitis Associated with Obesity

    Barrientos-Riosalido, A, Real, M, Bertran, L, Aguilar, C, Martinez, S, Parada, D, Vives, M, Sabench, F, Riesco, D, Castillo, DD, Richart, C, Auguet, T. 10/01/2023. International Journal Of Molecular Sciences. 24. PMID: 36674839. doi: 10.3390/ijms24021324

    Serum Arylesterase, Paraoxonase, and Lactonase Activities and Paraoxonase-1 Concentrations in Morbidly Obese Patients and Their Relationship with Non-Alcoholic Steatohepatitis

    Castañe, H, Jiménez-Franco, A, Martínez-Navidad, C, Placed-Gallego, C, Cambra-Cortés, V, Perta, AM, París, M, Castillo, DD, Arenas, M, Camps, J, Joven, J. 01/12/2023. Antioxidants. 12. PMID: 38136158. doi: 10.3390/antiox12122038

    Revisional bariatric surgery: On stage!

    Pereferrer, FS. 01/02/2023. Cirugia Espanola. 101. PMID: 36152959. doi: 10.1016/j.ciresp.2022.04.001

    Evolving mortality and clinical outcomes of hospitalized subjects during successive COVID-19 waves in Catalonia, Spain.

    Roso-Llorach A, Serra-Picamal X, Cos FX, Pallejà-Millán M, Mateu L, Rosell A, Almirante B, Ferrer J, Gasa M, Gudiol C, Moreno AM, Morales-Rull JL, Rexach M, Sabater G, Auguet T, Vidal F, Lerida A, Rebull J, Khunti K, Argimon JM, Paredes R. 01/12/2022. Global Epidemiology. 4. PMID: 35018339. doi: 10.1016/j.gloepi.2022.100071

    Rate of effect of surgical margins after breast conserving surgery and estimation of direct costs.

    Delgado C, Martínez S, Reig R. 01/11/2022. Cirugia Espanola. 100. PMID: 35850474. doi: 10.1016/j.cireng.2021.07.016

    Recent chromatographic and electrophoretic based methods for determining drugs of abuse in urine and oral fluid: A review from 2018 to June 2021

    Pascual-Caro, S, Borrull, F, Calull, M, Aguilar, C. 01/11/2022. Trac-Trends In Analytical Chemistry. 156. doi: 10.1016/j.trac.2022.116705

    Rate of effect of surgical margins after breast conserving surgery and estimation of direct costs

    De la Flor, M, Delgado, C, Martínez, S, Arenas, M, Gómez, M, Reig, R. 01/11/2022. Cirugia Espanola. 100

    Are Ingested or Inhaled Microplastics Involved in Nonalcoholic Fatty Liver Disease?

    Auguet, T, Bertran, L, Barrientos-Riosalido, A, Fabregat, B, Villar, B, Aguilar, C, Sabench, F. 01/10/2022. International Journal of Environmental Research and Public Health. 19. PMID: 36294076. doi: 10.3390/ijerph192013495

    NASH Presence is Associated with a Lower Weight Loss One and 2 Years After Bariatric Surgery in Women with Severe Obesity

    Sabench, F, Bertran, L, Vives, M, París, M, Aguilar, C, Martínez, S, Binetti, J, Real, M, Alibalic, A, Richart, C, Del Castillo, D, Auguet, T. 01/10/2022. Obesity Surgery. 32. PMID: 35792995. doi: 10.1007/s11695-022-06175-w

    Circulating pyruvate is a potent prognostic marker for critical COVID-19 outcomes

    Ceperuelo-Mallafré, V, Reverté, L, Peraire, J, Madeira, A, Maymó-Masip, E, López-Dupla, M, Gutierrez-Valencia, A, Ruiz-Mateos, E, Buzón, MJ, Jorba, R, Vendrell, J, Auguet, T, Olona, M, Vidal, F, Rull, A, Fernández-Veledo, S. 14/09/2022. Frontiers in immunology. 13. PMID: 36189213. doi: 10.3389/fimmu.2022.912579

    Increased Secreted Frizzled-Related Protein 5 mRNA Expression in the Adipose Tissue of Women with Nonalcoholic Fatty Liver Disease Associated with Obesity

    Bertran, L, Portillo-Carrasquer, M, Barrientos-Riosalido, A, Aguilar, C, Riesco, D, Martínez, S, Culebradas, A, Vives, M, Sabench, F, Del Castillo, D, Richart, C, Auguet, T. 01/09/2022. International Journal Of Molecular Sciences. 23. PMID: 36077270. doi: 10.3390/ijms23179871

    Homemade Pipette Tip Solid-Phase Extraction for the Simultaneous Determination of 40 Drugs of Abuse in Urine by Liquid Chromatography-Tandem Mass Spectrometry

    Pascual-Caro, S, Borrull, F, Calull, M, Aguilar, C. 01/09/2022. Separations. 9. doi: 10.3390/separations9090233

    Rivaroxaban Monotherapy in Patients with Pulmonary Embolism: Off-Label vs. Labeled Therapy

    Di Micco, P, Salazar, VR, Capitan, CF, Dentali, F, Cuervo, CG, Torres, JLF, Porras, JA, Fidalgo, A, Grandone, E, Meseguer, ML, Monreal, M. 01/08/2022. Life-Basel. 12. PMID: 36013307. doi: 10.3390/life12081128

    New Insights of OLFM2 and OLFM4 in Gut-Liver Axis and Their Potential Involvement in Nonalcoholic Fatty Liver Disease

    Bertran, L, Jorba-Martin, R, Barrientos-Riosalido, A, Portillo-Carrasquer, M, Aguilar, C, Riesco, D, Martínez, S, Vives, M, Sabench, F, Del Castillo, D, Richart, C, Auguet, T. 01/07/2022. International Journal Of Molecular Sciences. 23. PMID: 35806447. doi: 10.3390/ijms23137442

    Laparoscopic Sleeve Gastrectomy in Patients with Severe Obesity Restores Adaptive Responses Leading to Nonalcoholic Steatohepatitis

    Cabré, N, Luciano-Mateo, F, Chapski, DJ, Baiges-Gaya, G, Fernández-Arroyo, S, Hernández-Aguilera, A, Castañé, H, Rodríguez-Tomàs, E, París, M, Sabench, F, Del Castillo, D, del Bas, JM, Tomé, M, Bodineau, C, Sola-García, A, López-Miranda, J, Martín-Montalvo, A, Duran, RV, Vondriska, TM, Rosa-Garrido, M, Camps, J, Menéndez, JA, Joven, J. 01/07/2022. International Journal Of Molecular Sciences. 23. PMID: 35887177. doi: 10.3390/ijms23147830

    CD68 and CD83 immune populations in non-metastatic axillary lymph nodes are of prognostic value for the survival and relapse of breast cancer patients

    López, C, Bosch, R, Korzynska, A, García-Rojo, M, Bueno, G, García-Fontgivell, JF, González, SM, Navarro, AG, Colón, ES, Ribes, JC, Roszkowiak, L, Mata, D, Arenas, M, Gómez, J, Roso, A, Berenguer, M, Reverté-Villarroya, S, Llobera, M, Baucells, J, Lejeune, M. 01/07/2022. Breast Cancer. 29. PMID: 35137329. doi: 10.1007/s12282-022-01336-2

    Identification of the Potential Molecular Mechanisms Linking RUNX1 Activity with Nonalcoholic Fatty Liver Disease, by Means of Systems Biology

    Bertran, L, Eigbefoh-Addeh, A, Portillo-Carrasquer, M, Barrientos-Riosalido, A, Binetti, J, Aguilar, C, Chicote, JU, Bartra, H, Artigas, L, Coma, M, Richart, C, Auguet, T. 01/06/2022. Biomedicines. 10. PMID: 35740337. doi: 10.3390/biomedicines10061315

    Enoxaparin versus dalteparin or tinzaparin in patients with cancer and venous thromboembolism: The RIETECAT study

    Trujillo-Santos, J, Farge-Bancel, D, Pedrajas, JM, Gómez-Cuervo, C, Ballaz, A, Braester, A, Mahé, I, Villalobos, A, Porras, JA, Monreal, M. 01/05/2022. Research And Practice In Thrombosis And Haemostasis. 6. PMID: 35664535. doi: 10.1002/rth2.12736

    DigiPatICS: Digital Pathology Transformation of the Catalan Health Institute Network of 8 Hospitals-Planification, Implementation, and Preliminary Results

    Temprana-Salvador, J, López-García, P, Vives, JC, de Haro, L, Ballesta, E, Abusleme, MR, Arrufat, M, Marques, F, Casas, JR, Gallego, C, Pons, L, Mate, JL, Fernández, PL, López-Bonet, E, Bosch, R, Martínez, S, Cajal, SRY, Matias-Guiu, X. 01/04/2022. Diagnostics. 12. PMID: 35453900. doi: 10.3390/diagnostics12040852

    High rate of de novo esophagitis 5 years after sleeve gastrectomy: a prospective multicenter study in Spain

    Ferrer, JV, Acosta, A, García-Alementa, EM, García, AT, Del Castillo, D, Espelta, MV, del Val, ID, Lacorzana, JO, González-Argente, FX, Pagan, A, Martínez, S, García, M, Mayo-Ossorio, MD, Morante, J, Moreno, JD, Isabial, SO, Picardo, A, Sánchez, JD, Sánchez, R, Pardellas, H, Vilallonga, R. 01/04/2022. Surgery For Obesity And Related Diseases. 18. PMID: 34961735. doi: 10.1016/j.soard.2021.11.011

    Development of a Liquid Chromatography-Tandem Mass Spectrometry Method for the Simultaneous Determination of 40 Drugs of Abuse in Human Urine: Application to Real Cases

    Pascual-Caro, S, Borrull, F, Aguilar, C, Calull, M. 26/03/2022. Journal Of Analytical Toxicology. 47. PMID: 35348715. doi: 10.1093/jat/bkac020

    Resistin and IL-15 as Predictors of Invasive Mechanical Ventilation in COVID-19 Pneumonia Irrespective of the Presence of Obesity and Metabolic Syndrome

    Perpiñan, C, Bertran, L, Terra, X, Aguilar, C, Binetti, J, Lopez-Dupla, M, Rull, A, Reverté, L, Yeregui, E, Gómez-Bertomeu, F, Peraire, J, Auguet, T. 01/03/2022. Journal of personalized medicine. 12. PMID: 35330391. doi: 10.3390/jpm12030391

    Venous Thrombosis within 30 Days after Vaccination against SARS-CoV-2 in a Multinational Venous Thromboembolism Registry

    Bikdeli, B, Jimenez, D, Demelo-Rodriguez, P, Galeano-Valle, F, Porras, JA, Barba, R, Ay, C, Maly, R, Braester, A, Imbalzano, E, Rosa, V, Lecumberri, R, Siniscalchi, C, Fidalgo, A, Ortiz, S, Monreal, M. 01/02/2022. Viruses-Basel. 14. PMID: 35215771. doi: 10.3390/v14020178

    Lipocalin, Resistin and Gut Microbiota-Derived Propionate Could Be Used to Predict Metabolic Bariatric Surgery Selected Outcomes

    Auguet, T, Lopez-Dupla, M, Ramos, J, Bertran, L, Riesco, D, Aguilar, C, Ardévol, A, Pinent, M, Sabench, F, Del Castillo, D, Richart, C. 01/01/2022. Processes. 10. doi: 10.3390/pr10010143

    Fetuin-A, inter-a-trypsin inhibitor, glutamic acid and ChoE (18:0) are key biomarkers in a panel distinguishing mild from critical coronavirus disease 2019 outcomes

    Reverté, L, Yeregui, E, Olona, M, Gutiérrez-Valencia, A, Buzón, MJ, Martí, A, Gómez-Bertomeu, F, Auguet, T, López-Cortés, LF, Burgos, J, Benavent-Bofill, C, Boqué, C, García-Pardo, G, Ruiz-Mateos, E, Mestre, MT, Vidal, F, Viladés, C, Peraire, J, Rull, A. 01/01/2022. Clinical And Translational Medicine. 12. PMID: 35075803. doi: 10.1002/ctm2.704

Membres De L’equip

  • Responsable de grup

    • Dra. Teresa Auguet Quintillà

  • Equip de recerca

    • José Antonio Porras Ledante
    • David Riesco Acevedo
    • Salomé Martínez González
    • Jessica Binetti
    • Ajla Alibalic
    • Marta París Sans
    • Margarida Vives Espelta
    • Fàtima Sabench Pereferrer
    • Andrea Barrientos Riosalido
    • Laia Bertran Ramos
    • Elena Cristina Rusu Hutu
    • Javier Ugarte Chicote
    • Razie Mahmoodian
    • Carmen Aguilar Crespillo
    • Joanna Jurek
    • Helena Clavero
    • Joan Durán-Bertran
    • Javier Camarón
    • Carmen Arto
    • Balma Homedes

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